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Get a free sample of OS-01 FACE SPF (in all 4 tints!) with every order. Terms apply.

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Daily SPF Duo

Regular price $85.00$75.00
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The perfect pair for summer. Hydration and 100% mineral protection for the lips and face, powered by the OS-01 peptide.


OS-01 FACE SPF is a moisturizing SPF 30+ sunscreen available in untinted and 3 flexible tints.
OS-01 LIP SPF is a moisturizing SPF 15+ sunscreen for the lips.

OneSkin

Benefits

Hydrating mineral sunscreens that defend against aging on 3 fronts for healthier, more resilient skin and lips.

100% mineral SPFs

Non-nano zinc oxide prevents UV-induced damage including inflammation and collagen loss.01

Environmental protection

Potent antioxidants protect against oxidative stress caused by free radicals.01

UV + cellular protection

Shields skin from UV-induced damage and the effects of cellular aging.01

Find your OS-01 FACE SPF tint

Designed with a higher level of iron oxides, our tints provide flexible coverage that evens, blends and defends.

Active ingredients that complement the OS-01 peptide

  • 5 potent antioxidants that complement the OS-01 peptide

    1. Vitamin C
      An extra-stable version of vitamin C that has been shown to improve collagen and elastin production with exposure to UV light and blue light.
    2. Green Tea
      A Green tea extract that contains EGCG, a healing and protective polyphenol with 25-100x the antioxidant power of vitamin C.
    3. Acai extract
      An antioxidant compound that helps counteract damage from environmental pollutants and advanced glycation end products (AGEs).
    4. Tara Fruit Extract & Sunflower Sprout
      Potent plant extracts with highly efficient antioxidant capabilities to neutralize free radicals and protect skin from oxidative stress, along with preventing the synthesis of collagen degrading enzymes.
    5. Bisabolol
      A skin soothing agent known to improve skin tone and protect skin from daily damage including the incidence of sunburn.

5 potent antioxidants that complement the OS-01 peptide

  1. Vitamin C
    An extra-stable version of vitamin C that has been shown to improve collagen and elastin production with exposure to UV light and blue light.
  2. Green Tea
    A Green tea extract that contains EGCG, a healing and protective polyphenol with 25-100x the antioxidant power of vitamin C.
  3. Acai extract
    An antioxidant compound that helps counteract damage from environmental pollutants and advanced glycation end products (AGEs).
  4. Tara Fruit Extract & Sunflower Sprout
    Potent plant extracts with highly efficient antioxidant capabilities to neutralize free radicals and protect skin from oxidative stress, along with preventing the synthesis of collagen degrading enzymes.
  5. Bisabolol
    A skin soothing agent known to improve skin tone and protect skin from daily damage including the incidence of sunburn.

How it works

Powered by the OS-01 Senescence Peptideβ„’

The only peptide scientifically proven to reverse skin aging at the cellular level.Β 03,07

All Ingredients

OS-01 FACE SPF:

Active Ingredients: Zinc Oxide 17.5%

Inactive Ingredients (Untinted): Water (Aqua), Caprylic/Capric Triglyceride, Glycerin, Methyl Dihydroabietate, Cetearyl Alcohol, Cetyl Palmitate, Coco-Glucoside, Caprylyl/Capryl Glucoside, Sorbitan Palmitate, Sorbitan Olivate, Butyrospermum Parkii (Shea) Nut Extract, Ethyl Ferulate, Bisabolol, Allantoin, Hydrolyzed Jojoba Esters, Acacia Senegal Gum, Polyhydroxystearic Acid, Polyglyceryl-3 Polyricinoleate, Isostearic Acid, Lecithin, Tocopheryl Acetate, Tetrahexyldecyl Ascorbate, Decapeptide-52*, Oryza Sativa (Rice) Starch, Camellia Sinensis Leaf Extract, Euterpe Oleracea Fruit Extract, Caesalpinia Spinosa Fruit Pod Extract, Helianthus Annuus (Sunflower) Sprout Extract, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Xanthan Gum, Sodium Phytate, Propylene Glycol, Phenoxyethanol, Sodium Benzoate, Potassium Sorbate. *OS-01 Peptide

Inactive Ingredients (Light/Medium): Water (Aqua), Caprylic/Capric Triglyceride, Glycerin, Methyl Dihydroabietate, Cetearyl Alcohol, Cetyl Palmitate, Coco-Glucoside, Caprylyl/Capryl Glucoside, Sorbitan Palmitate, Sorbitan Olivate, Butyrospermum Parkii (Shea) Nut Extract, Ethyl Ferulate, Bisabolol, Allantoin, Hydrolyzed Jojoba Esters, Acacia Senegal Gum, Polyhydroxystearic acid, Polyglyceryl-3 Polyricinoleate, Isostearic Acid, Lecithin, Tocopheryl Acetate, Tetrahexyldecyl Ascorbate, Decapeptide-52*, Oryza Sativa (Rice) Starch, Camellia Sinensis Leaf Extract, Euterpe Oleracea Fruit Extract, Caesalpinia Spinosa Fruit Pod Extract, Helianthus Annuus (Sunflower) Sprout Extract, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Xanthan Gum, Sodium Phytate, Propylene Glycol, Phenoxyethanol, Sodium Benzoate, Potassium Sorbate, Triethoxycaprylylsilane, Alumina, Magnesium Oxides, Iron Oxide (CI 77491, CI 77492, CI 77499). *OS-01 Peptide

Inactive Ingredients (Medium/Deep): Water (Aqua), Caprylic/Capric Triglyceride, Glycerin, Methyl Dihydroabietate, Cetearyl Alcohol, Cetyl Palmitate, Coco-Glucoside, Caprylyl/Capryl Glucoside, Sorbitan Palmitate, Sorbitan Olivate, Butyrospermum Parkii Nut Extract, Ethyl Ferulate, Bisabolol, Allantoin, Hydrolyzed Jojoba Esters, Acacia Senegal Gum, Polyhydroxystearic acid, Polyglyceryl-3 Polyricinoleate, Isostearic acid, Lecithin, Tocopheryl Acetate, Tetrahexyldecyl Ascorbate, Decapeptide-52*, Oryza Sativa Starch, Camellia Sinensis Leaf Extract, Euterpe Oleracea Fruit Extract, Caesalpinia Spinosa Fruit Pod Extract, Helianthus Annuus (Sunflower) Sprout Extract, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Xanthan Gum, Sodium Phytate, Propylene Glycol, Citric Acid, Phenoxyethanol, Sodium Benzoate, Potassium Sorbate, Triethoxycaprylylsilane, Alumina, Magnesium Oxide. May Contain +/-Iron Oxide (CI 77491, CI 77492, CI 77499). *OS-01 Peptide

Inactive Ingredients (Deep): Water (Aqua), Caprylic/Capric Triglyceride, Glycerin, Methyl Dihydroabietate, Cetearyl Alcohol, Cetyl Palmitate, Coco-Glucoside, Caprylyl/Capryl Glucoside, Sorbitan Palmitate, Sorbitan Olivate, Butyrospermum Parkii Nut Extract, Ethyl Ferulate, Bisabolol, Allantoin, Hydrolyzed Jojoba Esters, Acacia Senegal Gum, Polyhydroxystearic acid, Polyglyceryl-3 Polyricinoleate, Isostearic acid, Lecithin, Tocopheryl Acetate, Tetrahexyldecyl Ascorbate, Decapeptide-52*, Oryza Sativa Starch, Camellia Sinensis Leaf Extract, Euterpe Oleracea Fruit Extract, Caesalpinia Spinosa Fruit Pod Extract, Helianthus Annuus (Sunflower) Sprout Extract, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Xanthan Gum, Sodium Phytate, Propylene Glycol, Citric Acid, Phenoxyethanol, Sodium Benzoate, Potassium Sorbate, Triethoxycaprylylsilane, Alumina, Magnesium Oxide. May Contain +/-Iron Oxide (CI 77491, CI 77492, CI 77499). *OS-01 Peptide

Drug Facts
Active Ingredients: Zinc Oxide 17.5% …………Purpose: Sunscreen

Uses
Helps prevent sunburn
If used as directed with other sun protection measures (see directions), decreases the risk of skin cancer and early skin aging caused by the sun.

Warnings
For external use only.
Do not use on damaged or broken skin.
When using this product keep out of eyes. Rinse with water to remove.
Stop use and ask a doctor if rash occurs.
Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

OS-01 LIP SPF:

Active ingredients: Zinc Oxide 5.5%

Inactive Ingredients: Simmondsia, Chinensis (Jojoba) Seed Oil, Ethylene/Propylene/Styrene Copolymer, Ethylhexyl Palmitate, Butyloctyl Salicylate, Caprylic/Capric Triglyceride, Water (Aqua), Garcinia Indica Seed Butter, Tocopheryl Acetate, Butylene/Ethylene/Styrene Copolymer, Glyceryl Oleate, Glyceryl Dioleate, Glycerin, Oleic Acid, Tribehenin, Sorbitan Isostearate, Palmitoyl Tripeptide-1, Dipalmitoyl Hydroxyproline, Trihydroxystearin, Sodium Hyaluronate, Glucomannan, Tetrahexyldecyl Ascorbate, Bisabolol, Decapeptide-52*, Ethylhexylglycerin, Caprylyl/Capryl Glucoside, Propanediol, Ectoin, Centella Asiatica Extract, Hippophae Rhamnoides Oil, Helianthus Annuus (Sunflower) Seed Oil, Copernicia Cerifera (Carnauba) Wax, Tocopherol, Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate, Polyhydroxystearic Acid, Polyglyceryl-3 Polyricinoleate, Isostearic acid, Lecithin, Beta-Sitosterol, Squalene, Lactic Acid, Palmitic acid. *OS-01 Peptide

Drug Facts

Active Ingredients: Zinc Oxide 5.5% …………Purpose: Sunscreen

Uses
Helps prevent sunburn
If used as directed with other sun protection measures (see directions), decreases the risk of skin cancer and early skin aging caused by the sun.

Warnings
For external use only.
Do not use on damaged or broken skin.
Stop use and ask a doctor if rash occurs.
Keep out of reach of children.

Citations

01Zonari A., et al. Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. J Cosmet Dermatol. 2024; 23: 2135-2144. doi:10.1111/jocd.16242

02 Zonari, A., et al. Clinical efficacy of OS-01 peptide formulation in reducing the signs of periorbital skin aging. Int J Cosmet Sci. 2025; 00: 1–11. doi:10.1111/ics.13042

03 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age Β  and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1

04 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims

05 New biological insights into skin aging around the eye. Journal of the American Academy of Dermatology, Volume 74, Issue 5, AB28 https://doi.org/10.1016/j.jaad.2016.02.112

06 Tagami, H. (2008), Location-related differences in structure and function of the stratum corneum with special emphasis on those of the facial skin. International Journal of Cosmetic Science, 30: 413-434. https://doi.org/10.1111/j.1468-2494.2008.00459.x

07 Boroni, M. et al. Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging. Clinical Epigenetics 12, 105. 2020. doi:10.1186/s13148-020-00899-1

Daily SPF Duo

4.6
Rated 4.6 out of 5 stars
Based on 296 reviews
Total 5 star reviews: 237 Total 4 star reviews: 29 Total 3 star reviews: 10 Total 2 star reviews: 11 Total 1 star reviews: 9
90%would recommend these products
296 reviews
  • L
    Linda
    Reviewing
    OS-01 LIP SPF
    I recommend this product
    Rated 5 out of 5 stars
    6 minutes ago
    5 Stars

    Arrived quickly. Feels nice on my lips. to need the SPF,, I will be spending a lot of time in the sun.

  • SK
    Shannon K.
    Verified Buyer
    Reviewing
    OS-01 LIP SPF
    I recommend this product
    Rated 5 out of 5 stars
    24 minutes ago
    New Favorite

    I have a lot of lip products. A. Lot. I tend to carry at least 8 around with me at any given time for different purposes (color, spf, feel, etc). This one has become what I reach for most frequently. The texture is a bit thick but very smooth and I enjoy that I cannot feel the spf. It also has a nice sheen. Whenever I want color, I just use a lip stain and layer this over the top, perfection!

  • JF
    Jacky F.
    Verified Buyer
    Reviewing
    OS-01 LIP SPF
    I recommend this product
    Rated 5 out of 5 stars
    3 hours ago
    Love the look, and feel!

    I am an outdoor water girl, so I know the importance of SPF lip protection. I have been applying a waterproof lip liner to outline, and fill in my lips. Then I apply the OS- 01 Lip SPF. It adds a nice shine, not greasy, top coat, and SPF protection. Looks great, gives a nice soft feel, as well as protecting. my lips from the Florida sun. It also looks, and feels great on it’t own. No white cast. Love the ingredients! What more can you ask for.

  • S
    Sandra
    Verified Buyer
    Reviewing
    OS-01 FACE SPF 30+
    I recommend this product
    Rated 5 out of 5 stars
    11 hours ago
    love the texture and finish

    It doesn't leave my skin shiny and at the same time it also moisturizes my skin. I have sunscreen in every purse.

  • SS
    Sandra S.
    Verified Buyer
    Reviewing
    OS-01 LIP SPF
    I recommend this product
    Rated 5 out of 5 stars
    14 hours ago
    Great so far

    I really like the applicator tip of the oneskin lip. Feels nice, isn't greasy or obnoxious, but stays on a long time. Also, it doesn't have a scent which usually drives me crazy because I'm sensitive to smells.

All Ingredients

Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. *OS-01 Peptide.

Citations

01Β Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin cells in the OneSkin lab. Explore more atΒ oneskin.co/claims
02Β Zonari, A., et al. npj Aging, 2023 03https://www.fda.gov/news-events/press-announcements/fda-advances-new-proposed-regulation-make-sure-sunscreens-are-safe-and-effective 04Β https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651070/ 05Β https://academic.oup.com/bbb/article/72/12/3211/5941013 06Β https://pubmed.ncbi.nlm.nih.gov/32522955/ 07Β https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068194/ `https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583886