Benefits
Multitasking moisturizer that addresses the common signs of aging on areas exposed most to the environment
Hydration
Boosts barrier function, allowing your skin retain moisture and stay hydrated.02
Firmness
Switches off the cells that degrade collagen, helping skin stay firm.01,03
Radiance
Enhances skin tone and texture, helping skin look and feel smooth and radiant.02
5-STAR REVIEWS
See why customers love OS-01 FACE
โI stopped using retinol which caused me to have rough, red patches, but kept my skin supple and smoothโฆand now using OneSkin I still have the wrinkle reduction effects and smooth skin without the negative effects.โ โ Tova N.
"I love this science-backed product. It truly makes a difference to my skin and has allowed me to pare down all the other lotions, potions, & products that were more reactive in nature vs this proactive approach. Not only have I saved money on my skincare routine, but I've witnessed even skin tone, more elasticity, and a reduction in forehead wrinkles. Would recommend again and again. Can't wait to see what they think of next!" โ Laura E.
"Itโs working great!!! It absorbs quickly. I see and feel a significant difference in my skinโs texture and radiance. My skin looks smoother and feels firmer. I highly recommend it for anyone serious about maintaining youthful, healthy glowing skin." โ Ildiko C.
"One skin really loves my skin. I no longer use retinoids and put up with their side effects. One skin feels so effective as it absorbs quickly leaving my skin more even, bouncy and fresh." โ Sarah B.
The proof is in the pictures
CLINICAL DATA
Visible results, scientifically validated
100
of participants had improved smoothness 02
95.5
of participants had improved firmness, radiance, and tone 02
90
of participants had improved elasticity 02
86
of participants had improved appearance of fine lines and wrinkles 02
The Science Behind OS-01 FACE
With age, skin becomes thinner, produces less collagen, proliferates at a slower rate, and accumulates damage. By analyzing key aging biomarkers in human skin samples before and after treatment in the lab, our scientists found that OS-01 FACE:
- Increases epidermal thickness 01
- Supports collagen biosynthesis pathways (increase in COL1A1 and collagen levels) 01,03
- Promotes cellular proliferation (increase in MKI67) 01
Expression of biomarkers associated with collagen production (COL1A1) and cell proliferation (MKi67) in the dermis of ex vivo human skin samples following treatment with nothing (No Treatment) or OS-01 FACE. (Zonari, A., et al. npj Aging, 2023) Note: In npj Aging publication, "Topical Pep 14" = OS-01 FACE
6 active ingredients that complement the OS-01 peptide
Getting started with OS-01 FACE
Follow these easy steps for optimal results
- Dispense 1-2 pumps onto fingers
- Gently massage into skin on the face and neck
- Use 2 times daily
How it works
Powered by the OS-01 Senescence Peptideโข
The only peptide scientifically proven to reverse skin aging at the cellular levelย 01,02,03
All Ingredients
Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. *OS-01 Peptide.
Citations
01 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age ย and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1
02 Zonari A., et al. Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. J Cosmet Dermatol. 2024; 23: 2135-2144. doi:10.1111/jocd.16242
03 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims
OS-01 FACE Topical Supplement
- PEPatricia E.Verified BuyerReviewingOS-01 FACE Refill PouchI recommend this productRated 5 out of 5 stars6 minutes agoLOVE IT!!
I love this face cream . It is easy to use, melts right in to your skin and I love that it is refillable and I can pull it out and see where I stand.
I have been using it religiously since late January and love the difference in my skin. I have always had large pores on my nose and they are becoming smaller!! YEAH!
- MMicheleReviewingOS-01 FACE Topical SupplementI recommend this productRated 5 out of 5 stars54 minutes ago5 Stars
I think I Finally found a great skincare line!! โค๏ธโค๏ธ
- GKGEORGIA K.Verified BuyerReviewingOS-01 FACE Refill PouchI recommend this productRated 5 out of 5 stars5 hours agoFace Product
I have been using the product for over a year and I think it definitely works. My skin has more elasticity than I see in my peers.
- SVStacia V.Verified BuyerRated 5 out of 5 starsYesterdayGreat!
This seems like itโs making my skin look and feel more hydrated and healthier. With skincare Iโm not always sure I can tell what is โsupposedโ to happen is happening but I used a full size bottle of this and Iโll be getting another. The only issue I have is with this type of bottle in general, itโs a pump that you canโt open so there always feels like there is wasted product. It would be great if they made a refillable container or some other kind of pump where you can unscrew the top and not lose product. In any case, I look forward to seeing even more results with the second bottle!
- SGSusan G.Verified BuyerReviewingOS-01 FACE Topical Supplement RefillI recommend this productRated 5 out of 5 starsYesterdayHappy face
I am so glad to use One Skin. My face is less red and my wrinkles are more smooth. I am an old gal of 75 with many years of sun. One Skin gets soaked in so quickly and with no shiny afterglow.
