Benefits
Multitasking moisturizer that addresses the common signs of aging on areas exposed most to the environment
Hydration
Boosts barrier function, allowing your skin retain moisture and stay hydrated.02
Firmness
Switches off the cells that degrade collagen, helping skin stay firm.01,03
Radiance
Enhances skin tone and texture, helping skin look and feel smooth and radiant.02
5-STAR REVIEWS
See why customers love OS-01 FACE
“I stopped using retinol which caused me to have rough, red patches, but kept my skin supple and smooth…and now using OneSkin I still have the wrinkle reduction effects and smooth skin without the negative effects.” – Tova N.
"I love this science-backed product. It truly makes a difference to my skin and has allowed me to pare down all the other lotions, potions, & products that were more reactive in nature vs this proactive approach. Not only have I saved money on my skincare routine, but I've witnessed even skin tone, more elasticity, and a reduction in forehead wrinkles. Would recommend again and again. Can't wait to see what they think of next!" – Laura E.
"It’s working great!!! It absorbs quickly. I see and feel a significant difference in my skin’s texture and radiance. My skin looks smoother and feels firmer. I highly recommend it for anyone serious about maintaining youthful, healthy glowing skin." – Ildiko C.
"One skin really loves my skin. I no longer use retinoids and put up with their side effects. One skin feels so effective as it absorbs quickly leaving my skin more even, bouncy and fresh." – Sarah B.
The proof is in the pictures
CLINICAL DATA
Visible results, scientifically validated
100
of participants had improved smoothness 02
95.5
of participants had improved firmness, radiance, and tone 02
90
of participants had improved elasticity 02
86
of participants had improved appearance of fine lines and wrinkles 02
The Science Behind OS-01 FACE
With age, skin becomes thinner, produces less collagen, proliferates at a slower rate, and accumulates damage. By analyzing key aging biomarkers in human skin samples before and after treatment in the lab, our scientists found that OS-01 FACE:
- Increases epidermal thickness 01
- Supports collagen biosynthesis pathways (increase in COL1A1 and collagen levels) 01,03
- Promotes cellular proliferation (increase in MKI67) 01
Expression of biomarkers associated with collagen production (COL1A1) and cell proliferation (MKi67) in the dermis of ex vivo human skin samples following treatment with nothing (No Treatment) or OS-01 FACE. (Zonari, A., et al. npj Aging, 2023) Note: In npj Aging publication, "Topical Pep 14" = OS-01 FACE
6 active ingredients that complement the OS-01 peptide
Getting started with OS-01 FACE
Follow these easy steps for optimal results
- Dispense 1-2 pumps onto fingers
- Gently massage into skin on the face and neck
- Use 2 times daily
How it works
Powered by the OS-01 Senescence Peptide™
The only peptide scientifically proven to reverse skin aging at the cellular level 01,02,03
All Ingredients
Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. *OS-01 Peptide.
Citations
01 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1
02 Zonari A., et al. Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. J Cosmet Dermatol. 2024; 23: 2135-2144. doi:10.1111/jocd.16242
03 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims
OS-01 FACE Topical Supplement
- VTVeronika T.Verified BuyerReviewingOS-01 FACE Refill PouchI recommend this productRated 5 out of 5 stars10 hours agoI love it
It makes my skin look young and healthy!
- MSMarie S.Verified BuyerReviewingOS-01 FACE Topical Supplement RefillI recommend this productRated 5 out of 5 stars15 hours agoGreat product.
I love this. It is the first time my face hasn’t felt rough in years.
Thank you.
- MCMelanie C.Verified BuyerRated 5 out of 5 stars18 hours agoLike magic!
Really a remarkable difference in my 54 year old skin using this product! I am active as a dancer, and have a healthy diet, so don't have any underlying skin issues, but the difference in texture and wrinkle depth is outstanding. I honestly noticed the difference immediately.
- LLeeReviewingOS-01 FACE Topical Supplement RefillI recommend this productRated 5 out of 5 starsYesterday5 Stars
Have been using for 3 months. My skin is softer and fine lines are reduced.
- DDDeirdre D.Verified BuyerReviewingOS-01 FACE Refill PouchI recommend this productRated 5 out of 5 stars3 days agoSmooth and effective
OS-01 face feels good on the face and isn’t greasy or irritating. But is it effective? That’s the question each person must be able to ask and determine themselves. The best evidence for me may be the fact that I’m not overly noticing or obsessing over fine lines and wrinkles on my face. I believe over time the results will speak for themselves.
