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Face

OS-01 FACE Topical Supplement

SUBSCRIPTION EXCLUSIVES

  • Plastic neutral refillable packaging
  • Exclusive early access to new products
  • Earn 2x points for free products on all recurring orders
  • Easily change, skip or cancel anytime

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Try it risk-free!Β 45 day money back guarantee.

  • Targets Dehydration, dullness, loss of elasticity
  • Suited to All skin types, safe for sensitive skin
  • Format Lightweight moisturizer

OS-01 FACE is a daily skin longevity treatment with the OS-01 Senescence Blocking Peptideβ„’, scientifically proven to target a root cause of skin aging to promote healthy, youthful skin on the face and neck.01,02

OneSkin

Benefits

Multitasking moisturizer that addresses the common signs of aging on areas exposed most to the environment

Hydration

Boosts barrier function, allowing your skin retain moisture and stay hydrated.02

Firmness

Switches off the cells that degrade collagen, helping skin stay firm.01,03

Radiance

Enhances skin tone and texture, helping skin look and feel smooth and radiant.02

5-STAR REVIEWS

See why customers love OS-01 FACE

β€œI stopped using retinol which caused me to have rough, red patches, but kept my skin supple and smooth…and now using OneSkin I still have the wrinkle reduction effects and smooth skin without the negative effects.” – Tova N.

"I love this science-backed product. It truly makes a difference to my skin and has allowed me to pare down all the other lotions, potions, & products that were more reactive in nature vs this proactive approach. Not only have I saved money on my skincare routine, but I've witnessed even skin tone, more elasticity, and a reduction in forehead wrinkles. Would recommend again and again. Can't wait to see what they think of next!" – Laura E.

"It’s working great!!! It absorbs quickly. I see and feel a significant difference in my skin’s texture and radiance. My skin looks smoother and feels firmer. I highly recommend it for anyone serious about maintaining youthful, healthy glowing skin." – Ildiko C.

"One skin really loves my skin. I no longer use retinoids and put up with their side effects. One skin feels so effective as it absorbs quickly leaving my skin more even, bouncy and fresh." – Sarah B.

CLINICAL DATA

Visible results, scientifically validated

100

of participants had improved smoothness 02

95.5

of participants had improved firmness, radiance, and tone 02

90

of participants had improved elasticity 02

86

of participants had improved appearance of fine lines and wrinkles 02

The Science Behind OS-01 FACE

With age, skin becomes thinner, produces less collagen, proliferates at a slower rate, and accumulates damage. By analyzing key aging biomarkers in human skin samples before and after treatment in the lab, our scientists found that OS-01 FACE:

  1. Increases epidermal thickness 01
  2. Supports collagen biosynthesis pathways (increase in COL1A1 and collagen levels) 01,03
  3. Promotes cellular proliferation (increase in MKI67) 01


Expression of biomarkers associated with collagen production (COL1A1) and cell proliferation (MKi67) in the dermis of ex vivo human skin samples following treatment with nothing (No Treatment) or OS-01 FACE. (Zonari, A., et al. npj Aging, 2023) Note: In npj Aging publication, "Topical Pep 14" = OS-01 FACE

Getting started with OS-01 FACE

Follow these easy steps for optimal results

  • Dispense 1-2 pumps onto fingers
  • Gently massage into skin on the face and neck
  • Use 2 times daily

How it works

Powered by the OS-01 Senescence Peptideβ„’

The only peptide scientifically proven to reverse skin aging at the cellular levelΒ 01,02,03

All Ingredients

Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. *OS-01 Peptide.

Citations

01 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age Β  and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1

02 Zonari A., et al. Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. J Cosmet Dermatol. 2024; 23: 2135-2144. doi:10.1111/jocd.16242

03 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims

OS-01 FACE Topical Supplement

4.7
Rated 4.7 out of 5 stars
Based on 5,574 reviews
Total 5 star reviews: 4.5k Total 4 star reviews: 737 Total 3 star reviews: 232 Total 2 star reviews: 65 Total 1 star reviews: 56
94%would recommend these products
5,574 reviews
  • KM
    Kim M.
    Verified Buyer
    Reviewing
    OS-01 FACE Refill Pouch
    I recommend this product
    Rated 5 out of 5 stars
    7 minutes ago
    Convenient way to refill and use all of product

    I'm a fan of OS-FACE, and the reason I like this refill isn't just because of the small discount, but rather because the removable pouch allows you to get every last drop of product out, which isn't usually the case with most packaging of skin products. It also is a bit more environmentally friendly in that it uses slightly less plastic. I wish there was more of a discount for buying the refill, but nevertheless I will be continuing to order refills for my OS-FACE product so that I can take advantage of the squeezable pouch to ensure no product goes to waste.

  • EK
    Elizabeth K.
    Verified Buyer
    Reviewing
    OS-01 FACE Refill Pouch
    I recommend this product
    Rated 5 out of 5 stars
    54 minutes ago
    01 Face is the Best!

    I’ve been using 01 Face for a little over a month. I was skeptical it would truly help tighten up the skin on my neck, or take redness away from my face, or fade the she spots on my hands. It’s done all three, in record time! A friend was staring at my face recently. I asked why she was staring. She said I like the way your bangs look, it’s more flattering. I laughed bc I haven’t changed anything about my bangs, it’s definitely my face that is looking better from 01 Face!

    Also, the 01 Face Refill Pouch is very easy to snap into the outer shell & so great the brand is so eco-friendly!

  • AC
    Amanda C.
    Verified Buyer
    Reviewing
    OS-01 FACE Refill Pouch
    I recommend this product
    Rated 5 out of 5 stars
    17 hours ago
    Gifted then snatched

    I bought this for my husband. But I tried it and really liked it, and the next thing I know, I’ve almost finished the first pouch. Sorry, not sorry! I was surprised to like this do much, as normally I use creams.

    My skin it normal-dry. I’m 38 in perimenopause, with a 3 year old- constantly exhausted. I am seeing an improvement in my skin. It looks rejuvenated, like new life has been put in. I’m very happy & will continue use!

  • DV
    Dian V.
    Verified Buyer
    Reviewing
    OS-01 FACE Refill Pouch
    I recommend this product
    Rated 5 out of 5 stars
    19 hours ago
    RESULTS

    I have used some of the best, but only this product has brought the question "what are you doing to your skin?". When that comes from one of your best friends - you know the see a significant change. Thanks for taking care of my skin and the planet by using a refill not another container.

  • DJ
    Deepak J.
    Verified Buyer
    Reviewing
    OS-01 FACE Refill Pouch
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    Hydrated

    Definitely makes my skin on my face more alive and hydrated.