Understanding The Epidermis: Functions, Composition, and More

6 min read

OCT 12, 2023 - by felip gerdes
October 12,2023

Understanding The Epidermis: Functions, Composition, and More

6 min read

OCT 12, 2023 - by felip gerdes
October 12,2023
The skin is the largest organ of the body. While it may appear somewhat simple compared to other organs, the skin is actually a complex and layered structure composed of the epidermis, dermis, and hypodermis layers. When developing a skin care routine for your skin, it’s important to understand which layer a skin characteristic manifests in so it can be properly addressed. Let’s take a closer look at the outermost layer of skin, the epidermis, and signs of epidermal conditions!
The skin is the largest organ of the body. While it may appear somewhat simple compared to other organs, the skin is actually a complex and layered structure composed of the epidermis, dermis, and hypodermis layers. When developing a skin care routine for your skin, it’s important to understand which layer a skin characteristic manifests in so it can be properly addressed. Let’s take a closer look at the outermost layer of skin, the epidermis, and signs of epidermal conditions!
01

What is the epidermis?

The epidermis is the thinnest layer of the skin and the body's first line of defense against pathogens, UV radiation, chemicals, and injury. Beyond this, the epidermis is responsible for maintaining our health and well-being in vital ways.

Where is the epidermis located?

While the epidermis covers the entire body, it is not uniformly distributed.1 Areas that frequently move like the neck and face have a thinner epidermal layer. The epidermis on your palms and soles of the feet, which experience near constant friction and pressure, are much thicker to protect these areas.

What is the function of the epidermis?

The epidermis is responsible for a number of critical functions that go far beyond skin’s superficial appearance.

Protection

One of the primary functions of the epidermis is to protect the body from external threats
. Keratinocytes and melanocytes are key cells in this process. Keratinocytes are the most common cells in the epidermis. These cells secrete lipids (fats) onto the skin surface to form a water barrier; this keeps the skin hydrated and helps protect skin from physical damage.1 Melanocytes are responsible for producing melanin, a protein that protects the skin cell against UV radiation.1 Melanin is what gives our skin color and tone. UV radiation induces melanin production within the skin causing the skin to tan.

Immunity

The epidermal layer is a crucial part of our ability to fight infection and disease. It protects the inner body from pathogens and other sources of infection. Additionally, the epidermis is armed with immune cells that are stationed to protect the skin from pathogens. 2

Homeostasis

The epidermis is also involved in regulating body temperature. The epidermis has specialized structures that help it dissipate excess heat from the body through sweat glands.3 As the water in our sweat evaporates, the skin cools.

Vitamin D

The skin is not only a passive agent of the body but also a factory dedicated to producing an essential vitamin in the body: vitamin D. The epidermis in particular is the layer that absorbs UVB radiation and converts chemical precursors into active ingredients that your liver uses to make vitamin D.4 Vitamin D helps us tackle various diseases and maintain strong immune, bone, brain, and mental health.

Layers of the epidermis

The epidermis is composed of several distinct layers, each with its unique characteristics and functions. These layers, from the outermost to the innermost, include:
  1. Stratum corneum - The stratum corneum is made of a layer of dead keratinocytes 3-30 cells thick. These dead skin cells help form a hydrophobic layer that locks moisture into the skin; this layer varies the most in thickness across the body.
  2. Stratum lucidum - This layer of the epidermis is only found in thicker skin like that in the palms of your hands and soles of your feet. Made of flattened dead skin cells it helps give thicker skin more structural strength.
  3. Stratum granulosum - This layer is responsible for transforming keratinocytes into the tough waterproofed cells that make up the outer layer of the epidermis. The stratum granulosum produces keratin precursors and the protein glue lamellar that hold the skin cells together
  4. Stratum spinosum - Sitting above the lowest layer of the epidermis, the stratum spinosum is made of spiky ridges of keratinocytes that help the skin move while binding it together. This layer of the skin also contains dendritic cells responsible for fighting disease and infection.
  5. Stratum basale
    - The deepest layer of the epidermis is made of an active stem cell that produces the keratinocytes which make up the vast majority of cells in the upper epidermis. It is also where melanocytes, the cells that give our skin tone and color can be found.1
01

What is the epidermis?

The epidermis is the thinnest layer of the skin and the body's first line of defense against pathogens, UV radiation, chemicals, and injury. Beyond this, the epidermis is responsible for maintaining our health and well-being in vital ways.

Where is the epidermis located?

While the epidermis covers the entire body, it is not uniformly distributed.1 Areas that frequently move like the neck and face have a thinner epidermal layer. The epidermis on your palms and soles of the feet, which experience near constant friction and pressure, are much thicker to protect these areas.

What is the function of the epidermis?

The epidermis is responsible for a number of critical functions that go far beyond skin’s superficial appearance.

Protection

One of the primary functions of the epidermis is to protect the body from external threats
. Keratinocytes and melanocytes are key cells in this process. Keratinocytes are the most common cells in the epidermis. These cells secrete lipids (fats) onto the skin surface to form a water barrier; this keeps the skin hydrated and helps protect skin from physical damage.1 Melanocytes are responsible for producing melanin, a protein that protects the skin cell against UV radiation.1 Melanin is what gives our skin color and tone. UV radiation induces melanin production within the skin causing the skin to tan.

Immunity

The epidermal layer is a crucial part of our ability to fight infection and disease. It protects the inner body from pathogens and other sources of infection. Additionally, the epidermis is armed with immune cells that are stationed to protect the skin from pathogens. 2

Homeostasis

The epidermis is also involved in regulating body temperature. The epidermis has specialized structures that help it dissipate excess heat from the body through sweat glands.3 As the water in our sweat evaporates, the skin cools.

Vitamin D

The skin is not only a passive agent of the body but also a factory dedicated to producing an essential vitamin in the body: vitamin D. The epidermis in particular is the layer that absorbs UVB radiation and converts chemical precursors into active ingredients that your liver uses to make vitamin D.4 Vitamin D helps us tackle various diseases and maintain strong immune, bone, brain, and mental health.

Layers of the epidermis

The epidermis is composed of several distinct layers, each with its unique characteristics and functions. These layers, from the outermost to the innermost, include:
  1. Stratum corneum - The stratum corneum is made of a layer of dead keratinocytes 3-30 cells thick. These dead skin cells help form a hydrophobic layer that locks moisture into the skin; this layer varies the most in thickness across the body.
  2. Stratum lucidum - This layer of the epidermis is only found in thicker skin like that in the palms of your hands and soles of your feet. Made of flattened dead skin cells it helps give thicker skin more structural strength.
  3. Stratum granulosum - This layer is responsible for transforming keratinocytes into the tough waterproofed cells that make up the outer layer of the epidermis. The stratum granulosum produces keratin precursors and the protein glue lamellar that hold the skin cells together
  4. Stratum spinosum - Sitting above the lowest layer of the epidermis, the stratum spinosum is made of spiky ridges of keratinocytes that help the skin move while binding it together. This layer of the skin also contains dendritic cells responsible for fighting disease and infection.
  5. Stratum basale
    - The deepest layer of the epidermis is made of an active stem cell that produces the keratinocytes which make up the vast majority of cells in the upper epidermis. It is also where melanocytes, the cells that give our skin tone and color can be found.1
02

What are common signs or symptoms of epidermis conditions?

Epidermal conditions take on a number of forms that can affect both the comfort and appearance of the skin. Here are just a few of the symptoms and causes of epidermal conditions.

Dermatitis and eczema

Dermatitis and eczema describe a group of inflammatory skin conditions that often share similar signs and symptoms, though the exact cause will vary. Symptoms include redness, itching, dryness, and even skin discoloration or flaky skin
. Eczema can be a result of your genetics or a result of your environment such as allergens, climate, infection, or even stress.5 Eczema and atopic dermatitis are also associated with a weakened
skin barrier. Because of the broad nature of these conditions, always consult a dermatologist to determine the best treatment options.

Hyperpigmentation or melasma

Hyperpigmentation and melasma are both skin conditions that appear as darkening or discolouration on certain areas of the skin. These conditions manifest as dark irregular patches on the skin often in areas that receive lots of sun exposure like the face, chest, and hands. These conditions can be the result of many factors but the most common include sun exposure, hormonal changes especially following a pregnancy, menopause and genetic factors.

Rough texture and scaling

Changes in skin texture is often a sign of an underlying skin condition or environmental source. Common symptoms include dryness, skin redness or irritation
, rough, and flaking skin. Root causes can include skin conditions like eczema, as well as infection, psoriasis, allergies, and even aging.5Treatment for changes in skin texture are varied because of the many underlying conditions that can cause these symptoms. Always consult your dermatologist before starting a treatment plan.
02

What are common signs or symptoms of epidermis conditions?

Epidermal conditions take on a number of forms that can affect both the comfort and appearance of the skin. Here are just a few of the symptoms and causes of epidermal conditions.

Dermatitis and eczema

Dermatitis and eczema describe a group of inflammatory skin conditions that often share similar signs and symptoms, though the exact cause will vary. Symptoms include redness, itching, dryness, and even skin discoloration or flaky skin
. Eczema can be a result of your genetics or a result of your environment such as allergens, climate, infection, or even stress.5 Eczema and atopic dermatitis are also associated with a weakened
skin barrier. Because of the broad nature of these conditions, always consult a dermatologist to determine the best treatment options.

Hyperpigmentation or melasma

Hyperpigmentation and melasma are both skin conditions that appear as darkening or discolouration on certain areas of the skin. These conditions manifest as dark irregular patches on the skin often in areas that receive lots of sun exposure like the face, chest, and hands. These conditions can be the result of many factors but the most common include sun exposure, hormonal changes especially following a pregnancy, menopause and genetic factors.

Rough texture and scaling

Changes in skin texture is often a sign of an underlying skin condition or environmental source. Common symptoms include dryness, skin redness or irritation
, rough, and flaking skin. Root causes can include skin conditions like eczema, as well as infection, psoriasis, allergies, and even aging.5Treatment for changes in skin texture are varied because of the many underlying conditions that can cause these symptoms. Always consult your dermatologist before starting a treatment plan.
03

Lifestyle tips to keep your skin healthy

There are several lifestyle practices that you can integrate into your routine to maintain a healthy epidermal layer. Here are some suggestions:

Minimizing UV exposure

High levels of UV radiation can damage the internal structure of cells within the epidermis.6Adequate sun protection throughout the day is key to skin health and preventing premature skin aging.
Sunscreen during winter and even on cloudy days is equally important for protecting your skin. Try to avoid UV exposure during peak UV hours by covering up or staying indoors.

Diet

Because cells in the epidermis are constantly replaced to replenish lost cells in the stratum corneum the body must be supplied with the energy and nutrients to rebuild the skin barrier.

Protein

Keratin, one of the main proteins in the epidermis, requires energy and the right amino acids to be built. Biotin, L-cysteine, zinc, and vitamins A and C are all necessary for the production of keratin as well as bolstering the health of the skin in ways that reduce signs of aging like wrinkles. Eggs, fatty fish, fruits, nuts, and seeds are all great sources of these keratin boosting components.7

Healthy Fats for a Strong Lipid Barrier

Unsaturated fats found in foods like fish, vegetable oils, nuts, seeds, avocados are used by the body to bolster the lipid layer of the skin. A diet high in Omega 3 fatty acids, polysaturated, and monounsaturated fats keep the skin barrier healthy and able to retain moisture by aiding in sebum production.8

Vitamin D

A lack of Vitamin D can be the cause of many skin conditions such as dermatitis or psoriasis. Although vitamin D is produced by the body, it can also be consumed. Consuming foods high in vitamin D like egg yolks, fatty fish like salmon or trout, mushrooms and cod liver oil can help especially if you are vitamin D deficient.9

Moisturize

In addition to aging, some skin conditions cause the skin to dry out. To combat these low levels of moisture be sure to incorporate a daily moisturizer into your routine. Ingredients such as hyaluronic acid
are highly effective at holding onto water molecules in skin, while lipids are helpful in locking in moisture.10

OS-01 Proprietary Peptide

If you’re looking for a simple yet effective regimen, try topical skin care products to address overall skin and epidermal health. Consider OneSkin’s Topical Supplements, OS-01 FACE our peptide moisturizer, OS-01 EYE our peptide eye cream, OS-01 SHIELD our peptide sunscreen, and OS-01 BODY our peptide body lotion.
The OS-01 peptide has been shown to11:
  • Increase skin’s epidermal thickness
  • Increase a key biomarker associated with collagen production, COL1A1
  • Decrease UV-induced collagen degradation enzyme, MMP3
  • Increase a key biomarker associated with hyaluronic acid production, HAS2
Treat your skin like the vital and complex organ that it is with OneSkin.
03

Lifestyle tips to keep your skin healthy

There are several lifestyle practices that you can integrate into your routine to maintain a healthy epidermal layer. Here are some suggestions:

Minimizing UV exposure

High levels of UV radiation can damage the internal structure of cells within the epidermis.6Adequate sun protection throughout the day is key to skin health and preventing premature skin aging.
Sunscreen during winter and even on cloudy days is equally important for protecting your skin. Try to avoid UV exposure during peak UV hours by covering up or staying indoors.

Diet

Because cells in the epidermis are constantly replaced to replenish lost cells in the stratum corneum the body must be supplied with the energy and nutrients to rebuild the skin barrier.

Protein

Keratin, one of the main proteins in the epidermis, requires energy and the right amino acids to be built. Biotin, L-cysteine, zinc, and vitamins A and C are all necessary for the production of keratin as well as bolstering the health of the skin in ways that reduce signs of aging like wrinkles. Eggs, fatty fish, fruits, nuts, and seeds are all great sources of these keratin boosting components.7

Healthy Fats for a Strong Lipid Barrier

Unsaturated fats found in foods like fish, vegetable oils, nuts, seeds, avocados are used by the body to bolster the lipid layer of the skin. A diet high in Omega 3 fatty acids, polysaturated, and monounsaturated fats keep the skin barrier healthy and able to retain moisture by aiding in sebum production.8

Vitamin D

A lack of Vitamin D can be the cause of many skin conditions such as dermatitis or psoriasis. Although vitamin D is produced by the body, it can also be consumed. Consuming foods high in vitamin D like egg yolks, fatty fish like salmon or trout, mushrooms and cod liver oil can help especially if you are vitamin D deficient.9

Moisturize

In addition to aging, some skin conditions cause the skin to dry out. To combat these low levels of moisture be sure to incorporate a daily moisturizer into your routine. Ingredients such as hyaluronic acid
are highly effective at holding onto water molecules in skin, while lipids are helpful in locking in moisture.10

OS-01 Proprietary Peptide

If you’re looking for a simple yet effective regimen, try topical skin care products to address overall skin and epidermal health. Consider OneSkin’s Topical Supplements, OS-01 FACE our peptide moisturizer, OS-01 EYE our peptide eye cream, OS-01 SHIELD our peptide sunscreen, and OS-01 BODY our peptide body lotion.
The OS-01 peptide has been shown to11:
  • Increase skin’s epidermal thickness
  • Increase a key biomarker associated with collagen production, COL1A1
  • Decrease UV-induced collagen degradation enzyme, MMP3
  • Increase a key biomarker associated with hyaluronic acid production, HAS2
Treat your skin like the vital and complex organ that it is with OneSkin.
Key Takeaways:
  • The epidermis is the outermost layer of the skin and serves as the body's first line of defense against various external threats such as pathogens, UV radiation, chemicals, and injuries.
  • The epidermis protects the body, plays a crucial role in the body's immune system, regulates body temperature, and produces vitamin D.
  • The epidermis is composed of several layers, including the stratum corneum, stratum lucidum, stratum granulosum, stratum spinosum, and stratum basale.
  • To maintain healthy skin, it's important to minimize UV exposure, follow a balanced diet rich in proteins, healthy fats, and vitamins (including vitamin D), and regularly moisturize to combat dryness and maintain moisture levels.
Key Takeaways:
  • The epidermis is the outermost layer of the skin and serves as the body's first line of defense against various external threats such as pathogens, UV radiation, chemicals, and injuries.
  • The epidermis protects the body, plays a crucial role in the body's immune system, regulates body temperature, and produces vitamin D.
  • The epidermis is composed of several layers, including the stratum corneum, stratum lucidum, stratum granulosum, stratum spinosum, and stratum basale.
  • To maintain healthy skin, it's important to minimize UV exposure, follow a balanced diet rich in proteins, healthy fats, and vitamins (including vitamin D), and regularly moisturize to combat dryness and maintain moisture levels.

Reviewed by Alessandra Zonari, PhD, Chief Scientific Officer (CSO) and Co-Founder of OneSkin

Alessandra earned her Master’s degree in stem cell biology, and her PhD in skin regeneration and tissue engineering at the Federal University of Minas Gerais in Brazil in collaboration with the 3B’s Research Group in Portugal. Alessandra did a second post-doctoral at the University of Coimbra in Portugal. She is a co-inventor of three patents and has published 20 peer-reviewed papers in scientific journals.

Reviewed by Alessandra Zonari, PhD, Chief Scientific Officer (CSO) and Co-Founder of OneSkin

Alessandra earned her Master’s degree in stem cell biology, and her PhD in skin regeneration and tissue engineering at the Federal University of Minas Gerais in Brazil in collaboration with the 3B’s Research Group in Portugal. Alessandra did a second post-doctoral at the University of Coimbra in Portugal. She is a co-inventor of three patents and has published 20 peer-reviewed papers in scientific journals.

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Cleanser Vs. Face Wash: Which Should I Reach For?
5 Common Perimenopause Skin Problems
Five Common Skin Problems Experienced in Perimenop...
You’re only as old as you feel, scientists are fin...
Collagen For Menopause: Why Is It Necessary For Healthy Skin Aging?
Collagen For Menopause: Why Is It Necessary For He...
Get to Know OneSkin’s Topical Supplements:

OS-

...
The Top 3 Benefits of Peptides for Skin
How to Use Peptides In Your Skincare Regimen to Optimize Your Health
How to Use Peptides In Your Skincare Regimen to Op...
peptide illustration
Peptides vs Retinol: Is One Better For Increasing ...
body skin
What Is Causing the Uneven Skin Tone On Your Body?
How To Boost Skin Moisture For Your Entire Body Fr...
Three Ways To Extend Your Skinspan Starting With Your Body Care Routine
Three Ways To Extend Your Skinspan Starting With Y...
free radicals
What Are Free Radicals and How Do They Impact Skin...
The Connection Between Mental Health, Age Percepti...
The Top 6 Best Antioxidants For Skin Health and Longevity
The Top 6 Best Antioxidants For Skin Health and Lo...
Zombie Cells
What are Zombie Cells & How Can We Remove Them?
SKIN CARE IS HEALTH CARE: WHY EXTENDING YOUR SKINS...
How chronic stress makes you age faster
What is Epidermal Thickness & Why Does it Matter?
Cell Turnover & Why It Slows As We Age
OneSkin Notable Mention: OneSkin Featured In Tony ...
101 Guide To Skin Tightening
101 Guide To Skin Tightening + 7 Noninvasive Metho...
Tight Feeling Skin: 3 Reasons Why
How to Reduce Skin Inflammation
How to Reduce Skin Inflammation & Redness
Niacinamide
Niacinamide Vs Retinol: How Do They Compare?
illustration of nutrients being absorb
Why Is Nutrient Absorption Key To Better Skin Heal...
Dr. David Sinclair
OneSkin Notable Mention: LifeSpan Episode 6 | The ...
skin repairing foods
The Top 10 Best Foods for Skin Repair
Closeup of a sun spot
Skin Hyperpigmentation 101: What It Is & How To Tr...
Are There Dangers of Retinol Cream Use?
What is Skin Elasticity & How Can You Improve It?
A Complete Guide to the 4 Stages of Wound Healing
4 Foods To Avoid During Wound Healing & Why
closeup portrait of a model
Celebrating Black History Month: A Discussion With...
What is the Function of Skin as a Protective Barrier
What is the Function of Skin as a Protective Barri...
Representation of the Black Community in Skin Care and Longevity
Representation of the Black Community in Skin Care...
Portrait of OneSkin Founders
Our Story: Learn more about the history of OneSkin...
What Is Senescence & Its Relationship To Aging?
What Is Senescence & Its Relationship To Aging?
Winter Skincare - How To Prevent Dry Skin this Sea...
Special Announcement: OneSkin to Donate 1% of Sale...
Biological Age: What is Biological Age, Why Does i...
What your skincare routine is missing (Hint. It’s ...
What is a peptide?
Peptides: the first piece of th...
Where Skin Health Meets Longevity
Health Is The New Wealth - One Skin Technologies
Health Is The New Wealth
Sleep: Nature’s Restart Button? - One Skin Technologies
The Correlation Between Sleep and Skin: Why It Mat...
How Relationships, Community, & Social Interaction...
OneSkin launches MolClock, the first skin-specific molecular clock to determine the biological age of human skin - One Skin Technologies
OneSkin launches MolClock, the first skin-specific...
Calorie Restriction And Intermittent Fasting: Eati...
Healthspan: A New Way To Think About Aging - One Skin Technologies
Healthspan: A New Way To Think About Aging

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More Than Skin Deep: How Physical Touch Predicts L...
6 Common In-Office Skin Treatments to Complement y...
What is Microneedling & Are There Alternatives?
How to Protect Against and Reverse Collagen Loss
Why Your Neck, Décolletage, and Hands Need Extra C...
What's the Connection Between Dehydration and Dry ...
How to Tighten Facial Skin Without Surgery
Exploring Alternatives to Botox
Best Practices for Moisturizing After Exfoliating
Recognizing Signs of Over-Exfoliated Skin
Healing Over-Exfoliated Skin: How to Treat Over-Ex...
OS-01 BODY SPF and OS-01 BODY: Even Better Togethe...
Introducing OS-01 BODY SPF: Triple power protectio...
Is Talc Bad for Skin? 7 Things You Need to Know
How Do We Know the OS-01 Peptide is Safe?
What Is Lanolin and Is It Bad for Your Skin?
Non-Comedogenic vs Comedogenic Skin Care Products
Mineral Oil: Facts, Myths, and Effects on Skin
The Problem with Paraffin for Skin
Petrolatum: Is it Safe or Harmful for Your Skin?
How Much Sunscreen to Apply
What Do Antioxidants Do For Skin and Why Should Yo...
Making Sense of SPFs: What’s the Difference Betwee...
How to Relieve Itchy Skin: Tips for Soothing Skin ...
What is The Difference Between UVA and UVB Rays?
Decoding the Connections Between Intrinsic & Extri...
Causes of Skin Itching
Causes of Skin Itching: Understanding the Reasons ...
How to Protect Your Skin from UVA and UVB Rays
Morning vs. Night Exfoliation: Determining the Bes...
How to Tell if Acne is Hormonal or Bacterial?
How to Know if Your Skin Barrier is Damaged
Tips for Managing Hormonal Breakouts
Understanding Hormonal Acne and Its Triggers
How to Repair & Restore Your Skin Barrier
How To Get Rid of Crepey Skin: 7 Solutions
When to Apply Sunscreen: Before or After Moisturiz...
How Alcohol Impacts Your Skin’s Health
The Effects of Alcohol on Your Skin's Aging Proces...
OS-01 FACE: Clinically Validated to Support Your S...
Can Alcohol Cause Breakouts?
The Proof is in the Peptide: 12-Week Clinical Stud...
Why Is My Neck Aging So Fast?
6 Factors That Contribute to Slow Skin Healing
6 Tips and Tricks for a Youthful Neck
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Addressing the Need for Indoor Sun Protection
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The Science of Sunburns: How to Treat and Prevent ...
Get to Know OneSkin’s Topical Supplements:
OS-01 F...
Pollution
Can Air Quality Affect Skin? Exploring the Impact ...
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Understanding the Relationship Between Sleep and U...
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Exploring the Effects of Quality Sleep on Your Ski...
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How to Improve Gut Microbiome
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Exploring Caloric Restriction and Its Effects on A...
woman stretching in bed
What’s the Connection Between Quality Sleep and Lo...
Healthy foods
Unlocking the Skin Benefits of Intermittent Fastin...
woman exercising
Why Exercise is a Game-Changer for Longevity
The Microbiome Diet and Its Effects on Skin
The Microbiome Diet and Its Effects on Skin
cold water
Cold Exposure: Hype or Longevity Boosting?
healthy foods
Eat Better, Live Longer: Top Foods for Longevity
How Environmental Stressors Affect Skin
How to Protect Your Skin from Everyday Environment...
OS-01 BODY
Pressing the Pause Button on Aging Skin: OS-01 BOD...
lip treatment
Lip Balm Ingredients: What to Look for and What to...
earth
Exploring Blue Zones: How Can We Optimize Our Heal...
Sunburn
Sun Exposure and Your Skin: 6 Things You Need to K...
Lips
Nurturing Your Lips: How to Keep Them Moisturized ...
Lips
Uncovering the 9 Causes of Dry Lips: Why Do Lips G...
How to Travel with Skin Care
How to Travel with Skin Care Products
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The Importance of Sunscreen: Why Should You Wear I...
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Lip Sunscreen: Do Lips Need SPF Protection?
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The Science of Gratitude
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Removing Sunscreen: Tips for Clean and Healthy Ski...
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Skin Explained: Is Skin An Organ?
UV Light and Skin
UV Light and Skin: Effects and Protection Strategi...
What is Epidermis
Understanding The Epidermis: Functions, Compositio...
Diving into dermis
Diving into Dermis: Functions and Significance
Why Do We Get Wrinkles
Unlocking the Science of Wrinkles: Causes, Formati...
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Why Skin Barrier is Important
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Ingredient Spotlight: Bentonite Uses, Benefits, & ...
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Hypodermis: Exploring Its Vital Functions
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The EU is Limiting Retinol in Skincare: Here’s Eve...
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Why You Should Use OS-01 FACE & OS-01 SHIELD Toget...
Age Gracefully: How to Manage Neck Wrinkles and Ac...
Discover Why Our New SPF Outperforms the Rest
How to Preserve Your Feet
How to Preserve Your Feet: 5 Strategies for Wrinkl...
Hands and Dermal Elasticity: Understanding and Man...
The Lip Lineage
The Lip Lineage: Exploring the Why Behind Wrinkled...
A Journey Through the Skin: How UV Radiation Cause...
How to Address Stomach Wrinkles
How to Address Stomach Wrinkles For Smoother Skin
How to Get Rid of Wrinkly Skin on Arms
A Scientific Approach to Addressing Wrinkly Skin o...
What is Skin Cycling
What is Skin Cycling? Understanding, Embracing, an...
How to Skin Cycle: A Guide to Optimize Your Skin C...
How Do Our Products Work Together?
Do You Know What Clinical Claims Really Mean?
What is Tinted Sunscreen?
What is Tinted Sunscreen?
two types of face wrinkles
2 Types of Wrinkles and Tips for Treating Them
 Zinc Oxide
The Top 5 Benefits of Zinc Oxide for Skin
Marionette Lines
Understanding Marionette Lines: Causes and Prevent...
How to Help Your Skin Act Younger
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The Science of Sunscreen: Understanding the Optima...
Better Elasticity, More Firmness: Discover OS-01 E...
Symptoms and Causes of Melasma on Face
Benefits of Sunscreen
Beyond UV Protection: 7 Surprising Ways Sunscreen ...
Navigating Anti-Aging Skincare: The industry, the ...
Sun spots
Sun Spots: Causes & 3 Prevention Tips
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Navigating Sunscreen Labels: Unwanted Ingredients ...
How to Prevent Skin Aging Before It Starts
Face vs. Body Sunscreen: Can You Use Body Sunscreen On Your Face?
Face vs. Body Sunscreen: Can You Use Body Sunscree...
Sun Damaged Skin: What it is, how you can prevent ...
Thick Skin vs Thin Skin
A Comprehensive Guide to Understanding the Differe...
How to Strengthen Your Skin
How to Strengthen Your Skin: A Guide to Thicker, H...
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An In-Depth Look at Glycerin: What is it and What ...
Glycerin Benefits for Skin
Exploring the Benefits of Glycerin for Skin Health
Difference Between Hydrating and Moisturizing
Exploring the Difference Between Hydrating and Moi...
3 Natural Ways to Keep Your Skin Hydrated and Glow...
How To Create A Hydrating Skin Care Routine For Dr...
Senotherapeutics, Senolytics, and Senomorphics -- ...
Cleansing 101: How to Wash Your Face the Right Way...
4 Essential Face Cleansing Steps to Achieving a Ra...
Scientific Breakthrough: OneSkin’s scientists show...
Dry Skin 101: How To Identify This Skin Type
How OS-01 Can Help Your Collagen Levels As You Age...
Developing a Skin Care Routine for Normal Skin: 4 ...
What is Normal Skin & Do I Have This Skin Type?
Skin Care Routine for Oily Skin
A Step-by-Step Guide to Creating the Perfect Skin ...
Understanding Oily Skin: Causes & Characteristics
Menopause and Skin Changes
7 Keys to Understanding Menopause and Skin Changes
Is This The Root Cause of Aging?
UV Damage Increases Cellular Senescence. Here's Ho...
Our Research Has Been Published in npj Aging
How To Reduce Hyperpigmentation by Targeting Cellu...
Perfect Skin Care Routine for Combination Skin
4 Steps to Crafting the Perfect Skin Care Routine ...
Managing Combination Skin
A Comprehensive Guide to Understanding and Managin...
Benefits Of Moringa Oil
An In-Depth Look At The Benefits Of Moringa Oil Fo...
How to Tighten the Skin Under Your Eyes
How to Tighten the Skin Under Your Eyes
7 Causes For Crepey Skin Under Eyes
Restoring Dry Skin Around The Eyes
101 Guide To Restoring Dry Skin Around The Eyes
How is OS-01 EYE different from OS-01 FACE?
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How to Remove Lingering Dead Skin Cells On the Fac...
Safe Beauty, Validated: Why OneSkin trusts SkinSAF...
Hallmarks Of Aging - One Skin Technologies
Hallmarks of Aging
What Is Sensitive Skin
What is Sensitive Skin?
Skin Tightening Ingredients
3 Skin Tightening Ingredients To Help Boost Skin H...
How OS-01 Works on Mature Skin
How OS-01 Works on Mature Skin
Is Fragrance Bad for Your Skin
Is Fragrance Bad for Your Skin?
Are Parabens Bad for Your Skin
Are Parabens Bad for Your Skin?
Target Cellular Senescence with the Highest Concen...
Can a Plant-Based Diet Really Increase Your Health...
Eye Skin Ages Faster: Here’s How OS-01 Can Help
Gut Health and Skin: How Are They Connected?
The Science Behind Why The Skin Around the Eyes Ag...
How OS-01 EYE Supports the Ultra-Thin Skin Around ...
How Do You Know When to Stop Using Retinol?
How To Heal Skin From Picking Your Face Too Much
Collagen And Elastin: What Role Do They Play In Sk...
Why We Want Skin To Be More, Not Less
Why We Want Skin To Be More, Not Less
What is Skin Inflammation? What Causes it?
How to Reverse (or Prevent) Aging Skin
Yes, You Need Sunscreen During Winter
Can You Use Hyaluronic Acid with Retinol?
Exploring the skin’s purpose in whole-body health
Stressed Skin
Stressed Skin: 4 Stress Effects on the Skin
What Does Hyaluronic Acid Do For Your Skin
What Does Hyaluronic Acid Do For Your Skin?
Good Genes vs. Good Habits: Which Impacts Your Lon...
How Does Sunscreen Work? How Long Does it Last?
How Does Sunscreen Work? How Long Does it Last?
What is the Best Skin Care Regimen for Aging Skin
What is the Best Skin Care Regimen for Aging Skin?
What happens to skin as a person ages?
What Causes Dark Circles Under and Around Your Eyes?
What Causes Dark Circles Under and Around Your Eye...
How to Brighten Eyes and Under-Eyes
Invasive vs. Non-Invasive Skincare: The pros and c...
6 Benefits of Jojoba Oil
6 Benefits of Jojoba Oil
What are the Benefits of Sulforaphane?
What are the Benefits of Sulforaphane?
What is Sustainable Packaging for Cosmetic Products?
What is Sustainable Packaging for Cosmetic Product...
7 Benefits of Andiroba Oil For Skin
Why is my Skin Peeling on My Face?
Dry, flaky skin
What Are The Causes Of Dry, Flaky Skin On Your Fac...
PREP enhances the effects of OS-01 FACE, and the p...
This is the Data to Look For When Choosing Skin Ca...
Why cellular senescence is more than just one of t...
Allantoin For Skin: A Comprehensive Guide
Ceramides For Skin: Everything You Need to Know
A Simplified Guide To The Different Skin Texture Types
A Simplified Guide To The Different Skin Texture T...
How OS-01 Works With Different Skin Types
How To Smooth Skin Texture On The Face: 4 Expert T...
What Causes Crepey Skin & Can It Be Avoided Altoge...
Does Niacinamide Help With Acne & Scarring?
Skin Microbiome: What It Is, Why it’s Important, A...
What Foods Cause Acne and Which Fight Against It?
What Foods Cause Acne and Which Fight Against It?
The 101 Guide To Understanding Acne-Prone Skin
The Top 4 Prickly Pear Benefits for Skin
What Is Exfoliation & Is It A Necessary Measure For Long-Term Skin Health?
What Is Exfoliation & Is It A Necessary Measure Fo...
OneSkin Notable Mention: Dave Asprey's The Human U...
How to Incorporate OneSkin’s OS-01 Topical Supplem...
Clean Beauty: What “clean” really means and why “s...
Retinol 101: Debunking Retinol as the Gold Standar...
Menopause & Skin: What you need to know
Take an Inside Look into Our Cutting-Edge R&D Plat...
101 Guide On The Benefits Of Cleansing Your Face
How OneSkin Developed the OS-01 Peptide
a smiling woman washing her face
Cleanser Vs. Face Wash: Which Should I Reach For?
5 Common Perimenopause Skin Problems
Five Common Skin Problems Experienced in Perimenop...
You’re only as old as you feel, scientists are fin...
Collagen For Menopause: Why Is It Necessary For Healthy Skin Aging?
Collagen For Menopause: Why Is It Necessary For He...
Get to Know OneSkin’s Topical Supplements:

OS-

...
The Top 3 Benefits of Peptides for Skin
How to Use Peptides In Your Skincare Regimen to Optimize Your Health
How to Use Peptides In Your Skincare Regimen to Op...
peptide illustration
Peptides vs Retinol: Is One Better For Increasing ...
body skin
What Is Causing the Uneven Skin Tone On Your Body?
How To Boost Skin Moisture For Your Entire Body Fr...
Three Ways To Extend Your Skinspan Starting With Your Body Care Routine
Three Ways To Extend Your Skinspan Starting With Y...
free radicals
What Are Free Radicals and How Do They Impact Skin...
The Connection Between Mental Health, Age Percepti...
The Top 6 Best Antioxidants For Skin Health and Longevity
The Top 6 Best Antioxidants For Skin Health and Lo...
Zombie Cells
What are Zombie Cells & How Can We Remove Them?
SKIN CARE IS HEALTH CARE: WHY EXTENDING YOUR SKINS...
How chronic stress makes you age faster
What is Epidermal Thickness & Why Does it Matter?
Cell Turnover & Why It Slows As We Age
OneSkin Notable Mention: OneSkin Featured In Tony ...
101 Guide To Skin Tightening
101 Guide To Skin Tightening + 7 Noninvasive Metho...
Tight Feeling Skin: 3 Reasons Why
How to Reduce Skin Inflammation
How to Reduce Skin Inflammation & Redness
Niacinamide
Niacinamide Vs Retinol: How Do They Compare?
illustration of nutrients being absorb
Why Is Nutrient Absorption Key To Better Skin Heal...
Dr. David Sinclair
OneSkin Notable Mention: LifeSpan Episode 6 | The ...
skin repairing foods
The Top 10 Best Foods for Skin Repair
Closeup of a sun spot
Skin Hyperpigmentation 101: What It Is & How To Tr...
Are There Dangers of Retinol Cream Use?
What is Skin Elasticity & How Can You Improve It?
A Complete Guide to the 4 Stages of Wound Healing
4 Foods To Avoid During Wound Healing & Why
closeup portrait of a model
Celebrating Black History Month: A Discussion With...
What is the Function of Skin as a Protective Barrier
What is the Function of Skin as a Protective Barri...
Representation of the Black Community in Skin Care and Longevity
Representation of the Black Community in Skin Care...
Portrait of OneSkin Founders
Our Story: Learn more about the history of OneSkin...
What Is Senescence & Its Relationship To Aging?
What Is Senescence & Its Relationship To Aging?
Winter Skincare - How To Prevent Dry Skin this Sea...
Special Announcement: OneSkin to Donate 1% of Sale...
Biological Age: What is Biological Age, Why Does i...
What your skincare routine is missing (Hint. It’s ...
What is a peptide?
Peptides: the first piece of th...
Where Skin Health Meets Longevity
Health Is The New Wealth - One Skin Technologies
Health Is The New Wealth
Sleep: Nature’s Restart Button? - One Skin Technologies
The Correlation Between Sleep and Skin: Why It Mat...
How Relationships, Community, & Social Interaction...
OneSkin launches MolClock, the first skin-specific molecular clock to determine the biological age of human skin - One Skin Technologies
OneSkin launches MolClock, the first skin-specific...
Calorie Restriction And Intermittent Fasting: Eati...
Healthspan: A New Way To Think About Aging - One Skin Technologies
Healthspan: A New Way To Think About Aging