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OS-01 BODY Topical Supplement

OS-01 BODY Topical Supplement

Revive thin, crepey skin with our daily body moisturizer, powered by the OS-01 PeptideTM.01



  • Improves skin texture, appearance, and hydration

  • Strengthens the skin barrier by up to +41%

  • Dermatologist tested, fragrance-free, safe for sensitive skin

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OS-01 BODY, Travel Size

Free travel-size OS-01 BODY with your first subscription

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BENEFITS

Nourishing body moisturizer and targeted treatment for thin, crepey skin

Smooth texture

Improves the root cause of crepey skin by supporting epidermal thickness for a firmer look and feel.01

Deep hydration

Replenishes and locks in hydration to keep skin soft, plump, and nourished.01

Barrier support

Fortifies the skin barrier to protect against daily stressors and moisture loss.01

5-STAR REVIEWS

See why customers love OS-01 BODY

“The skin on my legs was starting to look older, dry and crepey at 46. Now it is plump and youthful like it was 10 years ago after only a few weeks.” – Jen A.

"The One skin, OS-O1 Body, has been a game changer, within a few weeks I saw a remarkable difference in the quality of my skin, and my skin's appearance continues to improve with daily application. It now has a tighter, less dry look and the texture has almost returned to my premenopause condition..more moist and fresh in appearance. Science is everything, and One Skin has got the science spot on." – Tia T.


"I love this body lotion. My crepey skin is transforming. I wish I had taken pictures before I started using it but I have tried so many different products with no results that I didn’t have much confidence that this one would be any different. Boy was I wrong. I’m hoping that it will eventually get rid of all my dark spots on my skin. I will be a forever customer..."– Myra P.

CLINICAL DATA

Visible results, scientifically validated

93

of participants reported improved hydration 01

72

of participants reported improved appearance 01

70

of participants reported improved texture 01

41

Improvement in skin barrier function was measured 01

The Science Behind OS-01 BODY

Your skin is your largest organ and plays a vital role in your overall health as you age. Over time, it becomes thinner, more fragile, and less effective at protecting you from external aggressors. While most skincare focuses on the face, the other 97% of your skin is just as essential for longevity and well-being. OS-01 BODY is designed to strengthen your skin barrier from the neck down, keeping it resilient.

To evaluate OS-01 BODY’s effectiveness, our scientists measured epidermal thickness—a key indicator of barrier strength—using human skin samples in the lab. Results showed a 40% increase in epidermal thickness compared to untreated skin. This aligns with clinical findings demonstrating OS-01 BODY enhances skin barrier function by up to 41.49%.01


Shown in lab studies on ex vivo human skin samples by measuring epidermal thickness of histology images. Skin treated with OS-01 BODY displayed a significant average increase of +40% compared to skin with no treatment. Data was measured in triplicate.

Getting started with OS-01 BODY

Follow these easy steps for optimal results

  • Apply to arms, legs, chest, back, and stomach
  • Massage until absorbed
  • Use 2 times daily

How it works

Powered by the OS-01 Senescence Blocking Peptide™

The first and only peptide scientifically proven to reverse skin’s biological age.02,03

All Ingredients

Water, Glycerin, Limnanthes Alba (Meadowfoam) Seed Oil, Sorbitan Olivate, Avena Sativa (Oat) Kernel Oil, Squalane, Prunus Domestica Seed Oil, Saccharide Isomerate, Cetearyl Olivate, d-Panthenol, Mangifera Indica (Mango) Seed Butter, Tremella Fuciformis (Mushroom) Extract, Tocopheryl acetate, Decapeptide-52*, Allantoin, Asiaticoside, Centella Asiatica Extract, Sodium Hyaluronate Crosspolymer, Ceramide NP, Anadenanthera Colubrina Bark Extract, Lepidium Sativum Sprout Extract, Genistein, Niacinamide, Glycerol, Bentonite, Cetyl Palmitate, Sorbitan Palmitate, Lecithin, Xanthan Gum, Polyglyceryl-10 Laurate, Polyglyceryl-6 Oleate, Sorbitan Oleate, Glyceryl Caprylate, Polysorbate 80, Alcohol, Caprylyl Glycol, Sorbic Acid, Citric Acid, Sodium Citrate, Pentylene Glycol, Potassium Sorbate, Ethylhexylglycerin, Caprylhydroxamic Acid, Tetrasodium Glutamate Diacetate, Phenoxyethanol. *OS-01 Peptide

Citations

01Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims

02Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age   and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1

03Boroni, M. et al. Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging. Clinical Epigenetics 12, 105. 2020. doi:10.1186/s13148-020-00899-1

OS-01 BODY Topical Supplement

4.7
Rated 4.7 out of 5 stars
Based on 2,948 reviews
Total 5 star reviews: 2.3k Total 4 star reviews: 385 Total 3 star reviews: 140 Total 2 star reviews: 37 Total 1 star reviews: 41
93%would recommend these products
2,948 reviews
  • TJ
    Theresa J.
    Verified Buyer
    Reviewing
    OS-01 BODY
    I recommend this product
    Rated 5 out of 5 stars
    3 minutes ago
    Amazing

    It took a couple months of using this product everyday but at the end of the second month it was like I had completely new skin! Highly recommend

  • TM
    Tammy M.
    Verified Buyer
    Reviewing
    OS-01 BODY
    I recommend this product
    Rated 5 out of 5 stars
    12 hours ago
    Body Serum is a Game Changer

    Have been using these products for six months and am so pleased with the remarkable improvements! I will definitely continue.

  • AP
    Alison P.
    Verified Buyer
    Reviewing
    OS-01 BODY Topical Supplement
    Rated 3 out of 5 stars
    Yesterday
    Easy to use

    I’ve been using for about 4 weeks. No visible improvements yet but will continue until the bottle is done.

    OneSkin
    4 hours ago

    Hi Alison!

    Thank you for the review! We are happy to hear you are giving OS-01 BODY a chance!

    We recommend giving it at least 8 weeks to start seeing results! We have had customers start seeing results as soon as 6 weeks, but this can vary depending on the person!

    Please keep us posted on your progress! If you need personalized recommendations, feel free to reach out to support@oneskin.co!

  • HH
    Heather H.
    Verified Buyer
    Reviewing
    OS-01 BODY Topical Supplement
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    Body

    had my doubts for sure! Pleasantly surprised

    OneSkin
    4 hours ago

    Hi Heather!

    Thank you for the review!

    We are happy to hear you are enjoying OS-01 BODY!

  • JC
    Jodi C.
    Verified Buyer
    Reviewing
    OS-01 BODY Topical Supplement
    I recommend this product
    Rated 4 out of 5 stars
    Yesterday
    Too Early To Tell Yet

    I really like how this body lotion goes on. It absorbs really quickly and feels really nice. I haven't noticed any difference in the crepey skin areas yet, but I haven't been using it 4 months like the company suggests. I will give it that long at least and then update my review but for now I really like how it feels. It's not at all greasy, the smell is not offensive, just a really nice body lotion.

    OneSkin
    4 hours ago

    Hi Jodi!

    Thank you for the review! We are happy to hear you are enjoying OS-01 BODY!

    To date, it has been well-tolerated by our customers, but we are all unique and can experience changes in routine differently. Results can vary from person to person and can be affected by many things such as genetics, diet, exercise, age, environmental factors, etc. Another thing we'd like to note is while results may not be seen externally, there are many benefits from our peptide that are working internally to help the skin.

    The smell of our products can vary sometimes since we do not add any fragrance to the products(it's the natural smell of all the oils mixed together), so it won't affect the product's efficacy!

    Keep us updated on your progress! If you would like personalized advice, feel free to reach out to support@oneskin.co!