Peptides vs Retinol: Is One Better For Increasing Skin Longevity?
4 min read
MAY 16, 2022
SKIN CARE, SKIN SCIENCE
Peptides vs Retinol: Is One Better For Increasing Skin Longevity?
4 min read
MAY 16, 2022
SKIN CARE, SKIN SCIENCE
Peptides and retinol are two of the biggest players in the skin space with much of their celebrity status coming from their use in the “anti-aging” industry. But how promising is each active ingredient for skin longevity and which one – if not both – should you integrate into your skin health routine?Wondering, what is a peptide? Or, what do retinoids do? Let’s start with the basics:
Peptides and retinol are two of the biggest players in the skin space with much of their celebrity status coming from their use in the “anti-aging” industry. But how promising is each active ingredient for skin longevity and which one – if not both – should you integrate into your skin health routine?Wondering, what is a peptide? Or, what do retinoids do? Let’s start with the basics:
01
What is a peptide?
Peptides are small biological molecules containing two or more amino acids arranged in a chain-like fashion. Peptides that are linked together naturally become arranged in complex structures to form proteins (aka “polypeptides”), which are the molecules responsible for nearly every cell function. Collagen is the most abundant protein in the human body and is vital to skin health and longevity. The dermis (middle) layer of the skin is particularly important for skin longevity as this is where collagen-producing fibroblast cells reside. It’s widely accepted that collagen synthesis and subsequent collagen levels in the skin decrease with age, leading to changes in skin, such as fragility, increased fine lines and wrinkles, sagging, and loss of elasticity. [1]Peptide research and discovery is an exciting space for cutting-edge skincare. But, how to use peptides in skin care is the leading question. As direct supplementation of collagen to skin is difficult, skincare science has cleverly developed peptides that can promote collagen synthesis on a genetic level to rejuvenate skin from the inside out.Here are a few big players that are gaining attention for their collagen-boosting properties.
- Copper peptides are a type of carrier peptide that work together with antioxidant enzymes in the skin to protect collagen. This active ingredient also fights reactive oxygen species that can wreak havoc on other important molecules like DNA. [2]
- Palmitoyl pentapeptide-4 is another popular peptide to hit the market. Professionally known as Matrixyl, this ingredient has been shown to reduce wrinkles and increase skin elasticity in several biologically-relevant experiments. [3]
- OS-01 is a novel peptide that was originally developed in the OneSkin lab. This peptide is the first of its kind to reduce the level of cellular senescence in skin (which would otherwise result in the accumulation of “zombie” cells directly shown to cause skin damage and aging). The OS-01 peptide has been scientifically proven to increase key biomarkers associated with collagen and hyaluronic acid production. It also decreases biomarkers associated with aging and inflammation. [4]
01
What is a peptide?
Peptides are small biological molecules containing two or more amino acids arranged in a chain-like fashion. Peptides that are linked together naturally become arranged in complex structures to form proteins (aka “polypeptides”), which are the molecules responsible for nearly every cell function. Collagen is the most abundant protein in the human body and is vital to skin health and longevity. The dermis (middle) layer of the skin is particularly important for skin longevity as this is where collagen-producing fibroblast cells reside. It’s widely accepted that collagen synthesis and subsequent collagen levels in the skin decrease with age, leading to changes in skin, such as fragility, increased fine lines and wrinkles, sagging, and loss of elasticity. [1]Peptide research and discovery is an exciting space for cutting-edge skincare. But, how to use peptides in skin care is the leading question. As direct supplementation of collagen to skin is difficult, skincare science has cleverly developed peptides that can promote collagen synthesis on a genetic level to rejuvenate skin from the inside out.Here are a few big players that are gaining attention for their collagen-boosting properties.
- Copper peptides are a type of carrier peptide that work together with antioxidant enzymes in the skin to protect collagen. This active ingredient also fights reactive oxygen species that can wreak havoc on other important molecules like DNA. [2]
- Palmitoyl pentapeptide-4 is another popular peptide to hit the market. Professionally known as Matrixyl, this ingredient has been shown to reduce wrinkles and increase skin elasticity in several biologically-relevant experiments. [3]
- OS-01 is a novel peptide that was originally developed in the OneSkin lab. This peptide is the first of its kind to reduce the level of cellular senescence in skin (which would otherwise result in the accumulation of “zombie” cells directly shown to cause skin damage and aging). The OS-01 peptide has been scientifically proven to increase key biomarkers associated with collagen and hyaluronic acid production. It also decreases biomarkers associated with aging and inflammation. [4]
02
What is Retinol?
Retinol is a modified form of vitamin A, also known as retinoic acid. Vitamin A is crucial for central nervous system and immune system homeostasis, and even has antioxidant properties. [5] Retinoids can be broadly found on ingredients list as tretinoin, retinol, retinal, retinyl palmitate, or retinyl acetate – and depending on their concentration – they may induce negative side effects on your skin. Retinoids work by stimulating skin cell turnover and boosting collagen synthesis. By using retinol, dead skin cells at the surface of the skin are replaced with younger cells. Unfortunately, this rapid cell turnover can weaken the skin barrier temporarily after each use, leaving your skin and body vulnerable for a brief period of time, so proper skin care following use of retinol is critical for allowing the skin barrier to recover.Some stronger retinoids are prescription strength; only given by dermatologists to treat more stubborn skin conditions such as severe acne, fine lines, and/or dark spots to even out skin tone and improve overall skin texture. However, retinoid use can also (commonly) result in: skin irritation, skin dryness, skin sensitivity, skin flaking, and increased sensitivity to the sun.
02
What is Retinol?
Retinol is a modified form of vitamin A, also known as retinoic acid. Vitamin A is crucial for central nervous system and immune system homeostasis, and even has antioxidant properties. [5] Retinoids can be broadly found on ingredients list as tretinoin, retinol, retinal, retinyl palmitate, or retinyl acetate – and depending on their concentration – they may induce negative side effects on your skin. Retinoids work by stimulating skin cell turnover and boosting collagen synthesis. By using retinol, dead skin cells at the surface of the skin are replaced with younger cells. Unfortunately, this rapid cell turnover can weaken the skin barrier temporarily after each use, leaving your skin and body vulnerable for a brief period of time, so proper skin care following use of retinol is critical for allowing the skin barrier to recover.Some stronger retinoids are prescription strength; only given by dermatologists to treat more stubborn skin conditions such as severe acne, fine lines, and/or dark spots to even out skin tone and improve overall skin texture. However, retinoid use can also (commonly) result in: skin irritation, skin dryness, skin sensitivity, skin flaking, and increased sensitivity to the sun.
03
Are peptides better for certain skin types?
Given retinol’s harsh effects, certain skin types (especially sensitive skin) may not work well with any vitamin A derivatives. Additionally, you should avoid using retinol products if your skin is consistently exposed to the sun.Peptides, on the other hand, are typically suitable for any skin type.
03
Are peptides better for certain skin types?
Given retinol’s harsh effects, certain skin types (especially sensitive skin) may not work well with any vitamin A derivatives. Additionally, you should avoid using retinol products if your skin is consistently exposed to the sun.Peptides, on the other hand, are typically suitable for any skin type.
04
Do peptides and retinol serve a similar purpose?
The benefits of peptides are remarkably similar to those of retinol in terms of collagen synthesis and skin rejuvenation, however, peptides typically don’t induce negative side effects. Therefore, if you want the rejuvenation benefits of retinol without the negative side effects, a peptide moisturizer may be your answer.
04
Do peptides and retinol serve a similar purpose?
The benefits of peptides are remarkably similar to those of retinol in terms of collagen synthesis and skin rejuvenation, however, peptides typically don’t induce negative side effects. Therefore, if you want the rejuvenation benefits of retinol without the negative side effects, a peptide moisturizer may be your answer.
05
Are peptides better than retinol and why?
OneSkin’s proprietary peptide, OS-01, has been studied against retinol and found to induce similar benefits with none of the harsh side effects. In fact, when tested against retinol on human skin samples in the OneSkin lab, the OS-01 peptide increased biomarkers associated with collagen and hyaluronic acid similar to the levels induced by retinol. Perhaps more important, retinol significantly increased biomarkers associated with aging and inflammation, while the OS-01 peptide reliably decreased the activity of those same biomarkers. [4]If you are concerned about the side effects that come with retinol use and their impact on your long-term skin health, but still want the rejuvenation benefits of improved collagen production, consider using OneSkin's OS-01 topical supplements.
05
Are peptides better than retinol and why?
OneSkin’s proprietary peptide, OS-01, has been studied against retinol and found to induce similar benefits with none of the harsh side effects. In fact, when tested against retinol on human skin samples in the OneSkin lab, the OS-01 peptide increased biomarkers associated with collagen and hyaluronic acid similar to the levels induced by retinol. Perhaps more important, retinol significantly increased biomarkers associated with aging and inflammation, while the OS-01 peptide reliably decreased the activity of those same biomarkers. [4]If you are concerned about the side effects that come with retinol use and their impact on your long-term skin health, but still want the rejuvenation benefits of improved collagen production, consider using OneSkin's OS-01 topical supplements.
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06
How do peptides and retinol compare in terms of diminishing wrinkles?
In terms of comparing peptides vs retinol, OS-01 and retinol are neck and neck at promoting the production of collagen and hyaluronic acid in skin, two key factors in hindering the development of visible fine lines and wrinkles. The other large factor to consider when evaluating an ingredient’s ability to diminish fine lines and wrinkles is its ability to increase epidermal thickness of the skin. Like crinkled paper, the thicker the skin, the less visible the fine lines and wrinkle creases will be. By comparing epidermal thickness of skin samples in the lab when exposed to the OS-01 peptide vs retinol, retinol caused skin thickness to decrease, while the OS-01 peptide reliably increased skin thickness. [4] Therefore, the OS-01 peptide is expected to be superior at diminishing fine lines and wrinkles.When it comes to addressing peptides in general for their ability to decrease fine lines and wrinkle creases, there’s no clear answer. That’s because peptides are a broad class of molecules and each peptide has a different mechanism of action in the skin. Before assuming that a peptide-based product will improve fine lines and wrinkles, be sure to confirm that the peptide has been scientifically validated for its effects on skin health markers.
06
How do peptides and retinol compare in terms of diminishing wrinkles?
In terms of comparing peptides vs retinol, OS-01 and retinol are neck and neck at promoting the production of collagen and hyaluronic acid in skin, two key factors in hindering the development of visible fine lines and wrinkles. The other large factor to consider when evaluating an ingredient’s ability to diminish fine lines and wrinkles is its ability to increase epidermal thickness of the skin. Like crinkled paper, the thicker the skin, the less visible the fine lines and wrinkle creases will be. By comparing epidermal thickness of skin samples in the lab when exposed to the OS-01 peptide vs retinol, retinol caused skin thickness to decrease, while the OS-01 peptide reliably increased skin thickness. [4] Therefore, the OS-01 peptide is expected to be superior at diminishing fine lines and wrinkles.When it comes to addressing peptides in general for their ability to decrease fine lines and wrinkle creases, there’s no clear answer. That’s because peptides are a broad class of molecules and each peptide has a different mechanism of action in the skin. Before assuming that a peptide-based product will improve fine lines and wrinkles, be sure to confirm that the peptide has been scientifically validated for its effects on skin health markers.
07
Are peptides or Vitamin A a better ingredient for healthy skin longevity?
So who wins in the skin longevity showdown? The jury is still out, but the scientists at OneSkin caution against using retinol for improved skin longevity.Retinol can quickly degrade the skin barrier and increase the activity of genes associated with inflammation and aging [9], therefore using concentrated retinol or using retinol over an extended period of time has a high potential to compromise your long-term skin health, thereby diminishing your skin’s longevity. In contrast, OneSkin’s OS-01 peptide reliability improves internal and external skin health markers, making skin healthier from the inside out. Additionally, the OS-01 peptide is the first peptide proven to decrease skin’s biological age, thereby extending the length of time that skin is healthy and functional (aka your skinspan). [4]
07
Are peptides or Vitamin A a better ingredient for healthy skin longevity?
So who wins in the skin longevity showdown? The jury is still out, but the scientists at OneSkin caution against using retinol for improved skin longevity.Retinol can quickly degrade the skin barrier and increase the activity of genes associated with inflammation and aging [9], therefore using concentrated retinol or using retinol over an extended period of time has a high potential to compromise your long-term skin health, thereby diminishing your skin’s longevity. In contrast, OneSkin’s OS-01 peptide reliability improves internal and external skin health markers, making skin healthier from the inside out. Additionally, the OS-01 peptide is the first peptide proven to decrease skin’s biological age, thereby extending the length of time that skin is healthy and functional (aka your skinspan). [4]
08
Can peptides replace retinol and everyday use?
Both retinol and peptides have been shown to fight the signs of skin aging. But choosing one skin care ingredient over the other depends on what skin concern you are trying to treat.Peptides still have a ways to go in terms of testing en masse compared to numerous, published scientific studies performed with retinol. That being said, peptides are more skin-friendly than retinol by a long shot, due to their more moisturizing nature. This can make them more amenable to everyday use. On the other hand, retinol can be quite effective (yet harsh!) at treating acne, evening skin tone, and lessening the appearance of dark spots. As a rule of thumb, retinol should not be used every day even after skin has been introduced to it, as consistent retinol use of even low concentrations causes extreme sun sensitivity and can weaken the skin barrier.Can peptides and retinol be used in conjunction?Peptide-based products that are scientifically backed, such as OS-01’s Topical Supplements, will pair well with retinol as it can counteract some of retinol’s negative side effects.Be cautioned that by pairing retinol directly with a peptide product, the harsh side effects of retinol may be heightened due to its increased penetration in the skin [6,7,8]. A good way to get around this potential interaction is to alternate your use of retinol and peptide-based products.The moral of the story? Though retinol and peptide-based products are effective at improving collagen and hyaluronic acid production to produce rejuvenating effects, retinol may compromise your skin’s health in the long-term. Whether you choose to use retinol, peptides, or both, always be sure to consult a dermatologist if you experience negative side effects and try to ensure that the active ingredients within your topical skin care products are scientifically validated for their rejuvenation effects on skin.
08
Can peptides replace retinol and everyday use?
Both retinol and peptides have been shown to fight the signs of skin aging. But choosing one skin care ingredient over the other depends on what skin concern you are trying to treat.Peptides still have a ways to go in terms of testing en masse compared to numerous, published scientific studies performed with retinol. That being said, peptides are more skin-friendly than retinol by a long shot, due to their more moisturizing nature. This can make them more amenable to everyday use. On the other hand, retinol can be quite effective (yet harsh!) at treating acne, evening skin tone, and lessening the appearance of dark spots. As a rule of thumb, retinol should not be used every day even after skin has been introduced to it, as consistent retinol use of even low concentrations causes extreme sun sensitivity and can weaken the skin barrier.Can peptides and retinol be used in conjunction?Peptide-based products that are scientifically backed, such as OS-01’s Topical Supplements, will pair well with retinol as it can counteract some of retinol’s negative side effects.Be cautioned that by pairing retinol directly with a peptide product, the harsh side effects of retinol may be heightened due to its increased penetration in the skin [6,7,8]. A good way to get around this potential interaction is to alternate your use of retinol and peptide-based products.The moral of the story? Though retinol and peptide-based products are effective at improving collagen and hyaluronic acid production to produce rejuvenating effects, retinol may compromise your skin’s health in the long-term. Whether you choose to use retinol, peptides, or both, always be sure to consult a dermatologist if you experience negative side effects and try to ensure that the active ingredients within your topical skin care products are scientifically validated for their rejuvenation effects on skin.
Key Takeaways:
- Age-associated decrease in collagen levels in the skin causes visible signs of aging, including loss of elasticity and fine lines/wrinkles.
- Peptides’ anti-aging benefits come from their ability to promote collagen synthesis, among other benefits depending on the peptide
- Retinol improves collagen synthesis in skin, but often at the expense of skin dryness, inflammation, and sun sensitivity.
- Peptides are generally more gentle and moisturizing than retinol and therefore a better choice for those with a more sensitive skin type.
- The OS-01 peptide is the first peptide scientifically proven to reduce skin’s biological age.
Key Takeaways:
- Age-associated decrease in collagen levels in the skin causes visible signs of aging, including loss of elasticity and fine lines/wrinkles.
- Peptides’ anti-aging benefits come from their ability to promote collagen synthesis, among other benefits depending on the peptide
- Retinol improves collagen synthesis in skin, but often at the expense of skin dryness, inflammation, and sun sensitivity.
- Peptides are generally more gentle and moisturizing than retinol and therefore a better choice for those with a more sensitive skin type.
- The OS-01 peptide is the first peptide scientifically proven to reduce skin’s biological age.
References
- https://www.tandfonline.com/doi/full/10.1080/15569520701622951
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073405/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832239/
- Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. Npj Aging, 9(1), 1-15. 2023.
- https://pubmed.ncbi.nlm.nih.gov/9478051/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108505/
- https://www.mdpi.com/2079-9284/4/2/16/pdf
- https://onlinelibrary.wiley.com/doi/10.1002/adhm.201500634
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699641/
References
- https://www.tandfonline.com/doi/full/10.1080/15569520701622951
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073405/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832239/
- Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. Npj Aging, 9(1), 1-15. 2023.
- https://pubmed.ncbi.nlm.nih.gov/9478051/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108505/
- https://www.mdpi.com/2079-9284/4/2/16/pdf
- https://onlinelibrary.wiley.com/doi/10.1002/adhm.201500634
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699641/
Reviewed by Alessandra Zonari, PhD, Chief Scientific Officer (CSO) and Co-Founder of OneSkin
Alessandra earned her Master’s degree in stem cell biology, and her PhD in skin regeneration and tissue engineering at the Federal University of Minas Gerais in Brazil in collaboration with the 3B’s Research Group in Portugal. Alessandra did a second post-doctoral at the University of Coimbra in Portugal. She is a co-inventor of three patents and has published 20 peer-reviewed papers in scientific journals.
Reviewed by Alessandra Zonari, PhD, Chief Scientific Officer (CSO) and Co-Founder of OneSkin
Alessandra earned her Master’s degree in stem cell biology, and her PhD in skin regeneration and tissue engineering at the Federal University of Minas Gerais in Brazil in collaboration with the 3B’s Research Group in Portugal. Alessandra did a second post-doctoral at the University of Coimbra in Portugal. She is a co-inventor of three patents and has published 20 peer-reviewed papers in scientific journals.
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Skin Hyperpigmentation 101: What It Is & How To Tr...
Are There Dangers of Retinol Cream Use?
What is Skin Elasticity & How Can You Improve It?
Celebrating Black History Month: A Discussion With...
Celebrating Black History Month: A Discussion With...
Representation of the Black Community in Skin Care...
Our Story: Learn more about the history of OneSkin...
What Is Senescence & Its Relationship To Aging?
Winter Skincare - How To Prevent Dry Skin this Sea...
Special Announcement: OneSkin to Donate 1% of Sale...
Biological Age: What is Biological Age, Why Does i...
What your skincare routine is missing (Hint. It’s ...
What is a peptide?
Peptides: the first piece of th...
Peptides: the first piece of th...
Where Skin Health Meets Longevity
Health Is The New Wealth
The Correlation Between Sleep and Skin: Why It Mat...
How Relationships, Community, & Social Interaction...
OneSkin launches MolClock, the first skin-specific...
Calorie Restriction And Intermittent Fasting: Eati...
Healthspan: A New Way To Think About Aging
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What is The Difference Between UVA and UVB Rays?
Decoding the Connections Between Intrinsic & Extri...
How to Protect Your Skin from UVA and UVB Rays
Morning vs. Night Exfoliation: Determining the Bes...
How to Tell if Acne is Hormonal or Bacterial?
Tips for Managing Hormonal Breakouts
How to Know if Your Skin Barrier is Damaged
Understanding Hormonal Acne and Its Triggers
How to Repair & Restore Your Skin Barrier
How To Get Rid of Crepey Skin: 7 Solutions
When to Apply Sunscreen: Before or After Moisturiz...
How Alcohol Impacts Your Skin’s Health
The Effects of Alcohol on Your Skin's Aging Proces...
OS-01 FACE: Clinically Validated to Support Your S...
Can Alcohol Cause Breakouts?
The Proof is in the Peptide: 12-Week Clinical Stud...
Why Is My Neck Aging So Fast?
6 Tips and Tricks for a Youthful Neck
Addressing the Need for Indoor Sun Protection
The Science of Sunburns: How to Treat and Prevent ...
Get to Know OneSkin’s Topical Supplements:
OS-01 F...
OS-01 F...
Can Air Quality Affect Skin? Exploring the Impact ...
Understanding the Relationship Between Sleep and U...
Exploring the Effects of Quality Sleep on Your Ski...
How to Improve Gut Microbiome
Exploring Caloric Restriction and Its Effects on A...
What’s the Connection Between Quality Sleep and Lo...
Unlocking the Skin Benefits of Intermittent Fastin...
Why Exercise is a Game-Changer for Longevity
The Microbiome Diet and Its Effects on Skin
Cold Exposure: Hype or Longevity Boosting?
Eat Better, Live Longer: Top Foods for Longevity
How to Protect Your Skin from Everyday Environment...
Gut Health and Skin: How Are They Connected?
Pressing the Pause Button on Aging Skin: OS-01 BOD...
Lip Balm Ingredients: What to Look for and What to...
Exploring Blue Zones: How Can We Optimize Our Heal...
Sun Exposure and Your Skin: 6 Things You Need to K...
Nurturing Your Lips: How to Keep Them Moisturized ...
Uncovering the 9 Causes of Dry Lips: Why Do Lips G...
How to Travel with Skin Care Products
The Importance of Sunscreen: Why Should You Wear I...
Lip Sunscreen: Do Lips Need SPF Protection?
The Science of Gratitude
Removing Sunscreen: Tips for Clean and Healthy Ski...
Skin Explained: Is Skin An Organ?
UV Light and Skin: Effects and Protection Strategi...
Understanding The Epidermis: Functions, Compositio...
Diving into Dermis: Functions and Significance
Unlocking the Science of Wrinkles: Causes, Formati...
Ingredient Spotlight: Bentonite Uses, Benefits, & ...
Why Skin Barrier is Important
Hypodermis: Exploring Its Vital Functions
The EU is Limiting Retinol in Skincare: Here’s Eve...
Why You Should Use OS-01 FACE & OS-01 SHIELD Toget...
Age Gracefully: How to Manage Neck Wrinkles and Ac...
Discover Why Our New SPF Outperforms the Rest
How to Preserve Your Feet: 5 Strategies for Wrinkl...
Hands and Dermal Elasticity: Understanding and Man...
The Lip Lineage: Exploring the Why Behind Wrinkled...
A Journey Through the Skin: How UV Radiation Cause...
How to Address Stomach Wrinkles For Smoother Skin
A Scientific Approach to Addressing Wrinkly Skin o...
What is Skin Cycling? Understanding, Embracing, an...
How to Skin Cycle: A Guide to Optimize Your Skin C...
How Do Our Products Work Together?
Do You Know What Clinical Claims Really Mean?
What is Tinted Sunscreen?
2 Types of Wrinkles and Tips for Treating Them
The Top 5 Benefits of Zinc Oxide for Skin
Understanding Marionette Lines: Causes and Prevent...
How to Help Your Skin Act Younger
This is the Data to Look For When Choosing Skin Ca...
This is the Data to Look For When Choosing Skin Ca...
The Science of Sunscreen: Understanding the Optima...
Better Elasticity, More Firmness: Discover OS-01 E...
Symptoms and Causes of Melasma on Face
Beyond UV Protection: 7 Surprising Ways Sunscreen ...
Making Sense of Sunscreen: Understanding the Diffe...
Navigating Anti-Aging Skincare: The industry, the ...
Sun Spots: Causes & 3 Prevention Tips
Navigating Sunscreen Labels: Unwanted Ingredients ...
How to Prevent Skin Aging Before It Starts
Face vs. Body Sunscreen: Can You Use Body Sunscree...
Sun Damaged Skin: What it is, how you can prevent ...
A Comprehensive Guide to Understanding the Differe...
How to Strengthen Your Skin: A Guide to Thicker, H...
An In-Depth Look at Glycerin: What is it and What ...
Exploring the Difference Between Hydrating and Moi...
Exploring the Difference Between Hydrating and Moi...
Exploring the Benefits of Glycerin for Skin Health
3 Natural Ways to Keep Your Skin Hydrated and Glow...
3 Natural Ways to Keep Your Skin Hydrated and Glow...
How To Create A Hydrating Skin Care Routine For Dr...
How To Create A Hydrating Skin Care Routine For Dr...
Senotherapeutics, Senolytics, and Senomorphics -- ...
How OS-01 Can Help Your Collagen Levels As You Age
How OS-01 Can Help Your Collagen Levels As You Age...
4 Essential Face Cleansing Steps to Achieving a Ra...
Cleansing 101: How to Wash Your Face the Right Way...
Scientific Breakthrough: OneSkin’s scientists show...
Dry Skin 101: How To Identify This Skin Type
Developing a Skin Care Routine for Normal Skin: 4 ...
What is Normal Skin & Do I Have This Skin Type?
Moved - What is Normal Skin & Do I Have This Skin ...
A Step-by-Step Guide to Creating the Perfect Skin ...
Understanding Oily Skin: Causes & Characteristics
7 Keys to Understanding Menopause and Skin Changes
Is This The Root Cause of Aging?
UV Damage Increases Cellular Senescence. Here's Ho...
Our Research Has Been Published in npj Aging
How To Reduce Hyperpigmentation by Targeting Cellu...
What Do Antioxidants Do For Skin and Why Should Yo...
4 Steps to Crafting the Perfect Skin Care Routine ...
A Comprehensive Guide to Understanding and Managin...
An In-Depth Look At The Benefits Of Moringa Oil Fo...
How to Tighten the Skin Under Your Eyes
101 Guide To Restoring Dry Skin Around The Eyes Mo...
7 Causes For Crepey Skin Under Eyes
101 Guide To Restoring Dry Skin Around The Eyes
How is OS-01 EYE different from OS-01 FACE?
How to Remove Lingering Dead Skin Cells On the Fac...
Safe Beauty, Validated: Why OneSkin trusts SkinSAF...
What is Epidermal Thickness & Why Does it Matter?
Hallmarks of Aging
What is Sensitive Skin?
Cell Turnover & Why It Slows As We Age
How to Reduce Skin Inflammation & Redness
101 Guide To Skin Tightening + 7 Noninvasive Metho...
Tight Feeling Skin: 3 Reasons Why
3 Skin Tightening Ingredients To Help Boost Skin H...
How OS-01 Works on Mature Skin
Is Fragrance Bad for Your Skin?
Are Parabens Bad for Your Skin?
Target Cellular Senescence with the Highest Concen...
Can a Plant-Based Diet Really Increase Your Health...
Eye Skin Ages Faster: Here’s How OS-01 Can Help
How OS-01 EYE Supports the Ultra-Thin Skin Around ...
The Science Behind Why The Skin Around the Eyes Ag...
How Do You Know When to Stop Using Retinol?
How To Heal Skin From Picking Your Face Too Much
6 Factors That Contribute to Slow Skin Healing
4 Foods To Avoid During Wound Healing & Why
A Complete Guide to the 4 Stages of Wound Healing
Collagen And Elastin: What Role Do They Play In Sk...
What is the Function of Skin as a Protective Barri...
Why We Want Skin To Be More, Not Less
More Than Skin Deep: How Physical Touch Predicts L...
What is Skin Inflammation? What Causes it?
How to Reverse (or Prevent) Aging Skin
Yes, You Need Sunscreen During Winter
Can You Use Hyaluronic Acid with Retinol?
Exploring the skin’s purpose in whole-body health
Stressed Skin: 4 Stress Effects on the Skin
What Does Hyaluronic Acid Do For Your Skin?
Good Genes vs. Good Habits: Which Impacts Your Lon...
How Does Sunscreen Work? How Long Does it Last?
What is the Best Skin Care Regimen for Aging Skin?
What happens to skin as a person ages?
What Causes Dark Circles Under and Around Your Eye...
How to Brighten Eyes and Under-Eyes
Invasive vs. Non-Invasive Skincare: The pros and c...
6 Benefits of Jojoba Oil
What are the Benefits of Sulforaphane?
What is Sustainable Packaging for Cosmetic Product...
7 Benefits of Andiroba Oil For Skin
Why is my Skin Peeling on My Face?
What Are The Causes Of Dry, Flaky Skin On Your Fac...
PREP enhances the effects of OS-01 FACE, and the p...
Why cellular senescence is more than just one of t...
Allantoin For Skin: A Comprehensive Guide
Ceramides For Skin: Everything You Need to Know
A Simplified Guide To The Different Skin Texture T...
How OS-01 Works With Different Skin Types
How To Smooth Skin Texture On The Face: 4 Expert T...
What Causes Crepey Skin & Can It Be Avoided Altoge...
Does Niacinamide Help With Acne & Scarring?
Skin Microbiome: What It Is, Why it’s Important, A...
What Foods Cause Acne and Which Fight Against It?
The 101 Guide To Understanding Acne-Prone Skin
The Top 4 Prickly Pear Benefits for Skin
What Is Exfoliation & Is It A Necessary Measure Fo...
OneSkin Notable Mention: Dave Asprey's The Human U...
How to Incorporate OneSkin’s OS-01 Topical Supplem...
Clean Beauty: What “clean” really means and why “s...
Retinol 101: Debunking Retinol as the Gold Standar...
Menopause & Skin: What you need to know
Take an Inside Look into Our Cutting-Edge R&D Plat...
101 Guide on The Benefits of Cleansing Your Face
How OneSkin Developed the OS-01 Peptide
Cleanser Vs. Face Wash: Which Should I Reach For?
Five Common Skin Problems Experienced in Perimenop...
You’re only as old as you feel, scientists are fin...
Collagen For Menopause: Why Is It Necessary For He...
Get to Know OneSkin’s Topical Supplements:
...OS-
The Top 3 Benefits of Peptides for Skin
How to Use Peptides In Your Skincare Regimen to Op...
Peptides vs Retinol: Is One Better For Increasing ...
What Is Causing the Uneven Skin Tone On Your Body?
How To Boost Skin Moisture For Your Entire Body Fr...
Three Ways To Extend Your Skinspan Starting With Y...
What Are Free Radicals and How Do They Impact Skin...
The Connection Between Mental Health, Age Percepti...
The Top 6 Best Antioxidants For Skin Health and Lo...
What are Zombie Cells & How Can We Remove Them?
SKIN CARE IS HEALTH CARE: WHY EXTENDING YOUR SKINS...
How chronic stress makes you age faster
OneSkin Notable Mention: OneSkin Featured In Tony ...
Niacinamide Vs Retinol: How Do They Compare?
What Is Causing the Uneven Skin Tone On Your Body?
Why Is Nutrient Absorption Key To Better Skin Heal...
OneSkin Notable Mention: LifeSpan Episode 6 | The ...
The Top 10 Best Foods for Skin Repair
Skin Hyperpigmentation 101: What It Is & How To Tr...
Are There Dangers of Retinol Cream Use?
What is Skin Elasticity & How Can You Improve It?
Celebrating Black History Month: A Discussion With...
Celebrating Black History Month: A Discussion With...
Representation of the Black Community in Skin Care...
Our Story: Learn more about the history of OneSkin...
What Is Senescence & Its Relationship To Aging?
Winter Skincare - How To Prevent Dry Skin this Sea...
Special Announcement: OneSkin to Donate 1% of Sale...
Biological Age: What is Biological Age, Why Does i...
What your skincare routine is missing (Hint. It’s ...
What is a peptide?
Peptides: the first piece of th...
Peptides: the first piece of th...
Where Skin Health Meets Longevity
Health Is The New Wealth
The Correlation Between Sleep and Skin: Why It Mat...
How Relationships, Community, & Social Interaction...
OneSkin launches MolClock, the first skin-specific...
Calorie Restriction And Intermittent Fasting: Eati...
Healthspan: A New Way To Think About Aging