Gently exfoliates without irritation - Scientifically proven to enhance the penetration of the OS-01 peptide by up to 2x (01) - Supports natural balance of skin barrier and microbiome - 01: Shown by comparing the amount of the OS-01 peptide present in the dermis layer of ex vivo human skin samples exposed to OS-01 FACE and precleansed with PREP versus not pre-cleansed at all
Using PREP before OS-01 FACE enhances its hydration factor. 01 01 Shown by comparing the activity of a key biomarker associated with skin hydration (AQP3) before and after treatment of ex vivo human skin samples exposed to OS-01 FACE and pre-cleansed with PREP versus not pre-cleansed at all
Brand partner - skin safe - trusted choice - designed to benefit all skin types
Your Skin Longevity Routine ∞ 8 ONE SKIN PREP PREP EYE FACE SHIELD WHEN TO APPLY Apply 1-2 times daily. Cleansing nightly is recommended for most skin types to remove dirt, oil, makeup, and SPF. HOW TO APPLY Lather 1-2 pumps in damp hands to form a lightfoam. Then, gently massage onto damp skin. Rinse thoroughly and pat dry. WHERE TO APPLY Face and neck
KEEP Reusable Shell ONE SKIN PREP ONE SKIN PREP DISCARD (AFTER USE) Refill Pouch
ONE SKIN "Love this stuff. I have extremely sensitive skin, prone to redness and dryness. I use this cleanser twice a day, no problem, and visibly notice that OS-01 FACE works better when I do." Ellen B. Customer | PREP Facial Cleanser 200 mL / 6.76 Moz PREP ONE SKIN PREP
  • Gently exfoliates without irritation - Scientifically proven to enhance the penetration of the OS-01 peptide by up to 2x (01) - Supports natural balance of skin barrier and microbiome - 01: Shown by comparing the amount of the OS-01 peptide present in the dermis layer of ex vivo human skin samples exposed to OS-01 FACE and precleansed with PREP versus not pre-cleansed at all
  • Using PREP before OS-01 FACE enhances its hydration factor. 01 01 Shown by comparing the activity of a key biomarker associated with skin hydration (AQP3) before and after treatment of ex vivo human skin samples exposed to OS-01 FACE and pre-cleansed with PREP versus not pre-cleansed at all
  • Brand partner - skin safe - trusted choice - designed to benefit all skin types
  • Your Skin Longevity Routine ∞ 8 ONE SKIN PREP PREP EYE FACE SHIELD WHEN TO APPLY Apply 1-2 times daily. Cleansing nightly is recommended for most skin types to remove dirt, oil, makeup, and SPF. HOW TO APPLY Lather 1-2 pumps in damp hands to form a lightfoam. Then, gently massage onto damp skin. Rinse thoroughly and pat dry. WHERE TO APPLY Face and neck
  • KEEP Reusable Shell ONE SKIN PREP ONE SKIN PREP DISCARD (AFTER USE) Refill Pouch
  • ONE SKIN "Love this stuff. I have extremely sensitive skin, prone to redness and dryness. I use this cleanser twice a day, no problem, and visibly notice that OS-01 FACE works better when I do." Ellen B. Customer | PREP Facial Cleanser 200 mL / 6.76 Moz PREP ONE SKIN PREP

Starter Kit

PREP Facial Cleanser

573 reviews

200mL

Cleanser

PREP is a gentle daily facial cleanser that thorou...

$39 - Subscription / $45 - One Time Purchase

Select your plan

One-Time Purchase

Subscribe & Save
(Change, skip, or cancel anytime)
Deliver every
Try it risk-free! 45 day money back guarantee


Gently exfoliates without irritation - Scientifically proven to enhance the penetration of the OS-01 peptide by up to 2x (01) - Supports natural balance of skin barrier and microbiome - 01: Shown by comparing the amount of the OS-01 peptide present in the dermis layer of ex vivo human skin samples exposed to OS-01 FACE and precleansed with PREP versus not pre-cleansed at all
Using PREP before OS-01 FACE enhances its hydration factor. 01 01 Shown by comparing the activity of a key biomarker associated with skin hydration (AQP3) before and after treatment of ex vivo human skin samples exposed to OS-01 FACE and pre-cleansed with PREP versus not pre-cleansed at all
Brand partner - skin safe - trusted choice - designed to benefit all skin types
Your Skin Longevity Routine ∞ 8 ONE SKIN PREP PREP EYE FACE SHIELD WHEN TO APPLY Apply 1-2 times daily. Cleansing nightly is recommended for most skin types to remove dirt, oil, makeup, and SPF. HOW TO APPLY Lather 1-2 pumps in damp hands to form a lightfoam. Then, gently massage onto damp skin. Rinse thoroughly and pat dry. WHERE TO APPLY Face and neck
KEEP Reusable Shell ONE SKIN PREP ONE SKIN PREP DISCARD (AFTER USE) Refill Pouch
ONE SKIN "Love this stuff. I have extremely sensitive skin, prone to redness and dryness. I use this cleanser twice a day, no problem, and visibly notice that OS-01 FACE works better when I do." Ellen B. Customer | PREP Facial Cleanser 200 mL / 6.76 Moz PREP ONE SKIN PREP
  • Gently exfoliates without irritation - Scientifically proven to enhance the penetration of the OS-01 peptide by up to 2x (01) - Supports natural balance of skin barrier and microbiome - 01: Shown by comparing the amount of the OS-01 peptide present in the dermis layer of ex vivo human skin samples exposed to OS-01 FACE and precleansed with PREP versus not pre-cleansed at all
  • Using PREP before OS-01 FACE enhances its hydration factor. 01 01 Shown by comparing the activity of a key biomarker associated with skin hydration (AQP3) before and after treatment of ex vivo human skin samples exposed to OS-01 FACE and pre-cleansed with PREP versus not pre-cleansed at all
  • Brand partner - skin safe - trusted choice - designed to benefit all skin types
  • Your Skin Longevity Routine ∞ 8 ONE SKIN PREP PREP EYE FACE SHIELD WHEN TO APPLY Apply 1-2 times daily. Cleansing nightly is recommended for most skin types to remove dirt, oil, makeup, and SPF. HOW TO APPLY Lather 1-2 pumps in damp hands to form a lightfoam. Then, gently massage onto damp skin. Rinse thoroughly and pat dry. WHERE TO APPLY Face and neck
  • KEEP Reusable Shell ONE SKIN PREP ONE SKIN PREP DISCARD (AFTER USE) Refill Pouch
  • ONE SKIN "Love this stuff. I have extremely sensitive skin, prone to redness and dryness. I use this cleanser twice a day, no problem, and visibly notice that OS-01 FACE works better when I do." Ellen B. Customer | PREP Facial Cleanser 200 mL / 6.76 Moz PREP ONE SKIN PREP

Starter Kit

PREP Facial Cleanser

$39 - Subscription / $45 - One Time Purchase

573 reviews

200mL

Cleanser

PREP is a gentle daily facial cleanser that thorou...

Select your plan

One-Time Purchase

Subscribe & Save
(Change, skip, or cancel anytime)
Deliver every
Try it risk-free! 45 day money back guarantee


THE BREAKTHROUGH SCIENCE

DESIGNED TO MAKE OS-01 WORK HARDER

Scientifically proven to enhance the penetration of the OS-01 peptide by up to 2x. 01
PROMOTES THE HYDRATING EFFECTS OF OS-01 FACE

Using PREP before OS-01 FACE was shown to increase a key biomarker associated with hyaluronic acid production. 01
GENTLY EXFOLIATES WITHOUT IRRITATION

Gentle enzymes help remove dead skin cells and impurities without irritating the skin. This promotes the maintenance of healthy skin by ensuring effective cleansing takes place without compromising the skin's natural balance.
PROTECTS YOUR SKIN BARRIER & MICROBIOME

Free from detergents and harsh chemicals that are known to disrupt the beneficial lipids and microbes that help shield skin from environmental aggressors.

THE BREAKTHROUGH SCIENCE

DESIGNED TO MAKE OS-01 WORK HARDER

Scientifically proven to enhance the penetration of the OS-01 peptide by up to 2x. 01
PROMOTES THE HYDRATING EFFECTS OF OS-01 FACE

Using PREP before OS-01 FACE was shown to increase a key biomarker associated with hyaluronic acid production. 01
GENTLY EXFOLIATES WITHOUT IRRITATION

Gentle enzymes help remove dead skin cells and impurities without irritating the skin. This promotes the maintenance of healthy skin by ensuring effective cleansing takes place without compromising the skin's natural balance.
PROTECTS YOUR SKIN BARRIER & MICROBIOME

Free from detergents and harsh chemicals that are known to disrupt the beneficial lipids and microbes that help shield skin from environmental aggressors.

The Details

HOW TO INTEGRATE INTO YOUR ROUTINE

STEP 1: PREPYou’ll get the best results from any product by starting with freshly cleaned skin, so make PREP gentle cleanser the first step in your routine.

STEP 2: (optional) tonerSTEP 3: OS-01 EYESTEP 4: OS-01 FACESTEP 5: (optional) treatments including serums, retinoids, hyaluronic acid, and red light therapySTEP 6: OS-01 SHIELDSTEP 7: (optional) make-up

HOW TO APPLY

  • Lather 1-2 pumps of cleanser in damp hands until a light foam is formed
  • Gently massage onto damp skin on the face and neck
  • Rinse thoroughly and pat skin dry
  • Follow with the remainder of your routine
  • Use 2 times daily

Pro tip: Designed to gently remove dirt, oil, makeup, and sunscreen, PREP cleanser doubles the penetration 01 of OS-01 FACE when used together.




The Details

HOW TO INTEGRATE INTO YOUR ROUTINE

  • STEP 1: PREP
    • You’ll get the best results from any product by starting with freshly cleaned skin, so make PREP gentle cleanser the first step in your routine.
  • STEP 2: (optional) toner
    • Remove any debris leftover after your skin cleanser, balance the skin's pH, and prep skin for the rest of your routine.
  • STEP 3: OS-01 EYE
    • Follow your toner with our peptide eye cream to hydrate this sensitive skin area.
  • STEP 4: OS-01 FACE
    • Use this topical face cream as a daily moisturizer to lock in hydration and target aging at the source.
  • STEP 5: (optional) treatments
    • This includes heavier moisturizers, additional serums, retinoids, hyaluronic acid, and vitamin c.
  • STEP 6: OS-01 FACE SPF
    • Protect against UV damage and premature skin aging with this peptide sunscreen as a final skin prep step.
  • STEP 7: (optional) make-up
    • Complete your routine with makeup, if desired, to enhance your natural beauty and achieve a polished look.

HOW TO APPLY

  • Lather 1-2 pumps of PREP daily facial cleanser in damp hands until a light foam is formed
  • Gently massage onto lightly wet skin on the face and neck
  • Rinse thoroughly and pat skin dry
  • Follow with the remainder of your routine
  • Use 2 times daily

Pro tip: Designed to gently remove dead skin cells, dirt, oil, makeup, and sunscreen, PREP cleanser doubles the penetration 01 of OS-01 FACE when used together.




I love the refill packaging for this amazing product. This cleans my sensitive skin and sets up the right environment for the next product. I love how this line has made my skin look so much brighter and younger.

Nancy D.

Verified Buyer

One Skin feels like science on your skin. The skin prep is by far my favorite face wash - I know I can trust the brand to truly follow the science and focus on cellular care and repair. Can't recommend enough, I have all my friends and family using One Skin and loving it!
Claire P.

Verified Buyer

This is hands down the best face wash for all ages of skin. I bought this for my daughter who is struggling with sensitive skin and hormonal acne (age 21) and found that I love it for myself (age 50). I keep an extra in the shower and my 19 year old son even uses it! Perfect for a clean purifying wash!

Amy C.

Verified Buyer

I love the refill packaging for this amazing product. This cleans my sensitive skin and sets up the right environment for the next product. I love how this line has made my skin look so much brighter and younger.

Nancy D.

Verified Buyer

One Skin feels like science on your skin. The skin prep is by far my favorite face wash - I know I can trust the brand to truly follow the science and focus on cellular care and repair. Can't recommend enough, I have all my friends and family using One Skin and loving it!
Claire P.

Verified Buyer

This is hands down the best face wash for all ages of skin. I bought this for my daughter who is struggling with sensitive skin and hormonal acne (age 21) and found that I love it for myself (age 50). I keep an extra in the shower and my 19 year old son even uses it! Perfect for a clean purifying wash!

Amy C.

Verified Buyer