Discover the OS-01 peptide and see why retinol might not be the best option for your skin

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Try it risk-free! 45 day money back guarantee

Discover the OS-01 peptide and see why retinol might not be the best option for your skin

No items found

Try it risk-free! 45 day money back guarantee

For all its advantages, retinol also comes with some potentially serious downsides: redness, irritation, sensitivity and peeling. Our R&D team examined ex vivo human skin samples that were treated with OS-01 FACE versus retinol to observe the impact of both treatments on each layer of the skin.

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For all its advantages, retinol also comes with some potentially serious downsides: redness, irritation, sensitivity and peeling. Our R&D team examined ex vivo human skin samples that were treated with OS-01 FACE versus retinol to observe the impact of both treatments on each layer of the skin.

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Histology Images of ex vivo human skin samples - NO TREATMENT VS OS-01 FACE VS TOPICAL RETINOL (1.0%)

Skin that was treated with retinol experienced a peeling effect in the stratum corneum (top layer). Treatment with OS-01 FACE promoted a more cohesive stratum corneum, with a more defined general structure and enhanced cellular organization, indicating that the skin’s barrier was likely strengthened and cellular function was improved when treated with OS-01 FACE (Zonari, et al., 2023).When compared to retinol, OS-01 FACE provides similar benefits with none of the drawbacks.

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Skin that was treated with retinol experienced a peeling effect in the stratum corneum (top layer). Treatment with OS-01 FACE promoted a more cohesive stratum corneum, with a more defined general structure and enhanced cellular organization, indicating that the skin’s barrier was likely strengthened and cellular function was improved when treated with OS-01 FACE (Zonari, et al., 2023).When compared to retinol, OS-01 FACE provides similar benefits with none of the drawbacks.

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Love this product! I've been using for a little over a month and I've noticed a smoother skin texture and overall skin tone. Was using products containing retinol before, which can dry out your face (especially in the winter). After switching to OneSkin and cutting out retinol, my redness and fine lines are finally going away. Excited to see even more improvement with more use!

Clay D.

Verified Buyer

Definitely impressed. Noticeable improvements in texture and evenness in about 30 days. The only other topical product that produced noticeable results for was a retinol cream, but the results of this product were more significant.

Dan

Verified Buyer

I stopped using retinol which caused me to have rough, red patches, but kept my skin supple and smooth...and now using OneSkin I still have the wrinkle reduction effects and smooth skin without the negative effects.

Tova N.

Verified Buyer

Great stuff! After spending 6+ months frustrated with my retinol regiment, I gave OneSkin a try. Less than 2 moths in, my skin is already more plump and elastic. I'm excited to see what results are still in store!

Colin B.

Verified Buyer

I've used retinol for years and stopped when I started this product. I'm on my third month and my skin looks better than it did 10 years ago. I'm 58 and was recently told that my face continues to look younger. I'm looking forward to more supplements coming out from OneSkin.

Lisa C.

Verified Buyer

Buy now

Love this product! I've been using for a little over a month and I've noticed a smoother skin texture and overall skin tone. Was using products containing retinol before, which can dry out your face (especially in the winter). After switching to OneSkin and cutting out retinol, my redness and fine lines are finally going away. Excited to see even more improvement with more use!

Clay D.

Verified Buyer

Definitely impressed. Noticeable improvements in texture and evenness in about 30 days. The only other topical product that produced noticeable results for was a retinol cream, but the results of this product were more significant.

Dan

Verified Buyer

I stopped using retinol which caused me to have rough, red patches, but kept my skin supple and smooth...and now using OneSkin I still have the wrinkle reduction effects and smooth skin without the negative effects.

Tova N.

Verified Buyer

Great stuff! After spending 6+ months frustrated with my retinol regiment, I gave OneSkin a try. Less than 2 moths in, my skin is already more plump and elastic. I'm excited to see what results are still in store!

Colin B.

Verified Buyer

I've used retinol for years and stopped when I started this product. I'm on my third month and my skin looks better than it did 10 years ago. I'm 58 and was recently told that my face continues to look younger. I'm looking forward to more supplements coming out from OneSkin.

Lisa C.

Verified Buyer

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7+

Years of Research

To develop the OS-01 peptide, our research-first approach leveraged evidence-based data to navigate the complexities of skin aging.

900+

Peptides Screened

We screened over 900 peptides to develop OS-01: The first peptide proven to reverse skin’s biological age⁰¹ by reducing senescent cell accumulation⁰².

17+

Patents and Publications

Our proprietary technology, including our rigorous in-house R&D process and the OS-01 peptide, is supported by three peer-reviewed scientific publications and 14+ patents with many more pending.

3,700+

5-Star Reviews

Since launching in 2021, our proof goes beyond the lab with thousands of 5-star reviews and counting.

7+

Years of Research

To develop the OS-01 peptide, our research-first approach leveraged evidence-based data to navigate the complexities of skin aging.

900+

Peptides Screened

We screened over 900 peptides to develop OS-01: The first peptide proven to reverse skin’s biological age⁰¹ by reducing senescent cell accumulation⁰².

17+

Patents and Publications

Our proprietary technology, including our rigorous in-house R&D process and the OS-01 peptide, is supported by three peer-reviewed scientific publications and 14+ patents with many more pending.

3,700+

5-Star Reviews

Since launching in 2021, our proof goes beyond the lab with thousands of 5-star reviews and counting.