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Switches off senescent cells associated with aging to help skin behave like its younger self03

Boosts markers of healthy skin cell function, including collagen and hyaluronic acid biosynthesis04

Supports activation of cellular repair pathways04

The only peptide scientifically proven to reverse skin aging at the molecular level02

Extracted from the seeds of the Moringa tree, this extract protects skin cells against environmental pollutants that can trigger skin aging. 

This algae-derived extract helps reduce the appearance of dark circles and crow’s feet while enhancing overall skin luminosity. 

This biodesigned vegan collagen peptide is the first human mimetic and boosts elastin, laminin, collagen and fibronectin while most topical collagen fails to penetrate the skin barrier. 

Three active ingredients that support the OS-01 peptide to mitigate visible signs of aging around the eyes.

We’re currently conducting a clinical study on OS-01 EYE and we can’t wait to share the results! In the meantime, here are some encouraging results from our beta testers, who self-reported based on their experience with OS-01 EYE.

After 2 weeks of consistent use of OS-01 EYE (2x daily), beta testers observed the following visible improvements:

Crow’s Feet (92% of users reported improvement after 2 weeks of consistent use)

Under eye fine lines/wrinkles (85% of users reported improvement after 2 weeks of consistent use)

After 4 weeks of consistent use of OS-01 EYE (2x daily), beta testers observed the following additional visible improvements:

Puffiness (67% of users reported improvement after 4 weeks of consistent use)

Sagging under the eyes (67% of users reported improvement after 4 weeks of consistent use)

Sagging eyelids (67% of users reported improvement after 4 weeks of consistent use)

Dryness (92% of users reported improvement after 4 weeks of consistent use)

89% of beta testers would recommend OS-01 EYE to a friend.

OS-01 EYE Targets Accelerated Skin Aging Around the Eyes

The area around the eyes is some of the thinnest skin on our bodies–including an exceptionally thin dermal layer responsible for maintaining skin firmness and a similarly delicate stratum corneum that provides a barrier to the outside world. In fact, the stratum corneum around the eyes is on average just 3 layers thick, compared to 15+ layers on other areas of the face and body05, so eye area skin is exceptionally delicate and sensitive. This fact explains why skin around the eyes has been shown to age faster than the rest of the skin01, making it more susceptible to sagging and wrinkles. Given that the delicate skin in the eye area is inherently thinner and more sensitive, proper care is essential to maintain skin appearance and health, and address the specific needs of your skin type. Ensuring gentle care and nourishment for the entire eye area is vital to address the underlying and visible effects of aging and support the overall well-being of your skin.

We created OS-01 EYE to address the unique needs of this ultra-delicate skin, supercharged with the highest concentration of our OS-01 peptide to deliver unprecedented skin health benefits. This peptide eye cream is formulated to enhance skin elasticity and improve overall skin appearance in the delicate eye area, catering specifically to the requirements of this sensitive area.

OS-01 EYE Can Help Improve Collagen Biosynthesis & Maintenance

Our scientists exposed ex vivo eyelid skin samples to either nothing (No Treatment) or OS-01 EYE, then analyzed the effect on biomarkers associated with collagen production, COL1A1, and degradation, MMP1.

Expression analysis of biomarkers associated with collagen synthesis, COL1A1, and degradation, MMP1, of ex vivo eyelid skin samples before (No Treatment) and after exposure to OS-01 EYE. The results are the average of testing in 3 different ex vivo eyelid skins from donors of 42y, 59y, and 84y (*p<0.05 ).

We found that OS-01 EYE increased a key collagen production biomarker (COL1A1) and decreased a key collagen degradation biomarker (MMP1).06 This means that OS-01 EYE may help support skin’s firmness around the eyes by promoting collagen biosynthesis and retention at the molecular level.

OS-01 EYE Reduces Key Biomarkers Associated with Cellular Senescence & Inflammation

In lab studies, our scientists exposed ex vivo human eyelid skin samples to either nothing (No Treatment) or OS-01 EYE, then evaluated the effect on biomarkers associated with cellular senescence and aging, P16, and inflammation, IL-8.

For best results, cleanse your face with OneSkin PREP prior to use. Gently tap a small amount, one pump of OS-01 EYE, in a semi-circle around each eye. Follow with OS-01 FACE.

Where: From the under-eye to the eyelid and underneath the brow bone.

Water, Glycerin, Sorbitan Olivate, Squalane, Cetearyl Olivate, Butyrospermum Parkii (Shea) Butter, Simmondsia Chinensis (Jojoba) Seed Oil, Cystoseira Humilis Extract, d-Panthenol, Bentonite, Cetyl Palmitate, Sodium Hyaluronate Crosspolymer, Caprylhydroxamic Acid, Sorbitan Palmitate, Cellulose, Coffea Arabica (Coffee) Seedcake Extract, Allantoin, Fucus Vesiculosus Extract, Gluconolactone, Niacinamide, sh-Polypeptide-121, Sisymbrium Irio Seed Oil, Tocopheryl Acetate, Sorbic Acid, Caprylic/Capric Triglyceride, Ubiquinone, Lecithin, Decapeptide-52*, Sodium Chloride, Maltodextrin, Acetyl Hexapeptide-8, Moringa Oleifera Seed Extract, Glyceryl Caprylate, Caprylyl Glycol, Tetrasodium Glutamate Diacetate, Alcohol, Sodium Benzoate, Phenoxyethanol, Xanthan Gum. *OS-01 Peptide.

Not only does OS-01 EYE deliver longevity science to your skin, it also protects the longevity of our planet. 

The clear outer bottle can be kept and reused. The cartridge, containing the product, and the pump are disposable and can be discarded after use.

 will receive the complete set of packaging components in their  first shipment and  a refill cartridge/pump in every shipment thereafter.

 can choose whether you would like to receive the complete set of packaging components or just a refill cartridge/pump for a lower cost.

Expression analysis of biomarkers associated with senescence, P16, and inflammation, IL-8, of ex vivo eyelid skin before (No Treatment) and after exposure to OS-01 EYE. The results are the average of testing in 3 different ex vivo eyelid skins from donors of 42y, 59y, and 84y (*p<0.05 ).

We found that OS-01 EYE decreased a key senescence biomarker (P16) and a key inflammation biomarker (IL-8).06

With a higher concentration of the OS-01 peptide, OS-01 EYE is designed to decrease the effects of senescent burden around the eyes – which can help reduce visible signs of aging and soothe periocular skin.

By conducting an epidermal thickness analysis of 

 human skin samples, our scientists found that skin treated with OS-01 FACE displayed a significant increase in epidermal thickness of 23.15% (

 human skin samples to OS-01 FACE and retinol, then analyzed key biomarkers associated with skin aging, CDKN2A, and collagen production, COL1A1, to determine their potential effect on skin at a molecular level. 

Expression of biomarkers associated with skin aging (CDK2NA), and collagen production (COL1A1) in the dermis of 

human skin samples following treatment with nothing (No Treatment), OS-01 FACE, or 1% retinol *p<0.05 (Zonari, et al).

Our products are 100% free from fragrance, parabens, sulfates, lanolin, MCI/MI, DEA, heavy metals, talc, petrolatum/paraffin/mineral oil, gluten, and do not contain unnecessary emulsifiers, preservatives, and solvents. We prioritize the use of key ingredients that ensure a safe and effective formulation, delivering the best results for your skin care needs.

OS-01 EYE, our peptide eye cream, was rated 

, Good for Sensitive Skin by SkinSAFE. SkinSAFE helps people with sensitive skin types find best-in-class products with breakthrough, AI-powered science and patch testing data in partnership with Mayo Clinic. Given that the delicate eye area is particularly prone to sensitivity, you can trust in the gentle and skin-friendly formulation of OS-01 EYE to provide the care and nourishment your eyes deserve, without compromising on effectiveness or safety.

OS-01 EYE was given the Good Face Project Approved Seal

, meaning that OS-01 EYE complies with their high standard of safety and is free from 1,500+ toxic chemicals which impact long-term health and the environment.

02Measured in lab studies on human skin samples, and using MolClock, a proprietary algorithm that predicts skin's biological age (

Boroni, M. et al. Clinical Epigenetics, 2020

) 03 Shown in lab studies on fibroblast cultures from patient derived samples (

04 Shown in lab studies on human skin samples (

06 Shown in lab studies on human eyelid skin samples (OneSkin manuscript in preparation)

POWERED BY OS-01 SENESCENCE BLOCKING PEPTIDE TM

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The skin around your eyes has been shown to age faster than the rest of the skin with higher levels of cellular senescence.01 OS-01 EYE, our peptide eye cream, is formulated with the highest concentration of our OS-01 peptide to help target aging at the molecular level. This eye cream is designed to cater to the delicate eye area, providing targeted care and addressing the signs of aging where they matter most.

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OS-01 EYE Starter Kit | Community

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https://www.oneskin.co/policies/terms-of-service and https://www.oneskin.co/policies/privacy-policy

OS-01 EYE Starter Kit | Community

OS-01 EYE Starter Kit | Community

THE BREAKTHROUGH SCIENCE

POWERED BY OS-01 SENESCENCE BLOCKING PEPTIDE^{^TM}

THE BREAKTHROUGH SCIENCE

POWERED BY OS-01 SENESCENCE BLOCKING PEPTIDE^{^TM}