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PREP Starter Kit OTP

PREP Starter Kit OTP

Rated 4.8 out of 5
Based on 379 reviews



Try it risk-free! 30 day money back guarantee

We are currently low in stock. As such, we are temporarily only offering 60 day subsciptions. 30 day and 90 day subscriptions will be be available once stock is replenished. Once you receive your 50 mL bottle, you will be able to modify your subscription to 30 or 90 days.

Try it risk-free! 30 day money back guarantee  

Pair it with OS-01 FACE Topical Supplement for a complete skin longevity treatment

Shop OS-01 FACE

Clean, balanced, healthy skin

Formulated to deliver a deep yet gentle cleanse that won’t disrupt healthy skin function.

  Developed by Longevity Scientists

  Safe & Clean

  Vegan & Cruelty-Free

  For All Skin Types

  Sulfate & Fragrance-Free

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How to Use

Lather 1-2 pumps of cleanser in damp hands until a light foam is formed. Using circular movements, gently massage onto damp skin. Rinse thoroughly and pat dry. For best results, follow with OS-01 FACE Topical Supplement.

Where: Face and neck.

When: 1-2 times daily, depending on your skin type. Cleansing nightly is recommended for most skin types to remove dirt, oil, makeup, and SPF. Pro tip: Since your skin is still clean from the night before, skipping a morning cleanse will prevent potential dryness.

Key Benefits

PREP thoroughly removes impurities, light makeup, and sunscreen without disrupting natural barrier function, so skin is ready to benefit from the rest of your skin health routine.



Removes impurities that can prevent your skin from absorbing topical treatments to ensure maximum results from OS-01, including enhanced barrier function and diminished signs of aging.



Helps skin shed dead cells to speed renewal and turnover.



Preserves the beneficial lipids and microbes that shield skin from environmental aggressors. 



Protects against water loss while preventing pore congestion in acne-prone skin.



Soothes as it cleanses to support even the most reactive skin.


Water, Sodium Laurylglucosides Hydroxypropylsulfonate, Cocamidopropyl Hydroxysultaine, Disodium Lauryl Sulfosuccinate, Glycerin, Sodium Hydroxypropylphosphate Laurylglucoside Crosspolymer, Sodium Grapeseed Amidopropyl PG-Dimonium Chloride Phosphate, Hydrolyzed Opuntia Ficus-Indica Flower Extract, Breu Branco Resin, Caprylyl Glycol, Phenoxyethanol, Lonicera Japonica (Honeysuckle) Flower Extract, Niacinamide, Sorbic Acid, Arnica Montana (Arnica Flower) Extract, Tetrasodium Glutamate Diacetate


How does PREP specifically prepare my skin for the OS-01 FACE Topical Supplement?

Dead skin cells, dirt, and ingredients in makeup and sunscreen can create build-up on the skin that prevents products from fully absorbing. PREP gently dissolves this build-up without disrupting your natural lipid barrier so that OS-01 FACE can absorb more readily–ensuring you see maximum results from our OS-01 peptide. 

Is PREP safe / clean?

Like all OneSkin products, PREP is clean, vegan and cruelty-free. Using our high standards for scientific rigor, we formulate the safest, most effective products possible.

The Environmental Working Group (EWG) rates skincare ingredients on a scale of 1-10, with a score of 1 being the safest. PREP received an average score of 1.235 and a weighted average of 1.095 based on the EWG’s SkinDeep Cosmetics Database scoring guidelines

PREP was also tested for human sensitization (RIPT - a clinical study to assess skin irritation) and no adverse effects were found.

PREP was rated 91% and Top Allergan Free by SkinSAFE. SkinSAFE helps people with sensitive skin find best-in-class products with breakthrough AI-powered science and patch testing data in partnership with the Mayo Clinic.

How should I integrate PREP into my current skincare routine?

Use PREP every evening to cleanse your skin, followed immediately by OS-01 FACE. If you have oily skin and prefer to cleanse both morning and night, you can also use PREP to wash your face at the start of each day. 

PREP has not been shown to produce adverse reactions when used with other products and can be safely incorporated into your current routine.

Remember, it’s always best to patch test any new skincare product.

Do you ship internationally?

We currently ship to the U.S. and Canada. We are working on adding international shipping options. Sign up for our newsletter for updates as we continue to expand.

What is the approximate shelf life for PREP? 

PREP has a shelf life of 24 months. 

How should PREP be stored?

PREP can be stored at room temperature.

Is PREP packaging recyclable?

Yes! The PREP bottle is 100% recyclable. 

 How does PREP refillable packaging work?

Your shipment will come with an empty bottle and a pouch of cleanser to fill the bottle. If you are signed up for a subscription, please keep the bottle, as you will be sent a new pouch on a recurring basis to refill the bottle. If you are making a one-time purchase, you can indicate whether you would like to be shipped a bottle and pouch or just the pouch. 

How long will one bottle of PREP last?

The 200 ml bottle will last approximately 1-2 months, when used as directed.

Have any more questions?

For our comprehensive FAQ list click here.

I'm astonished how much more effective OS-01 is when combined with your new cleanser. OS-01 was dramatically more effective immediately after my first use with OneSkin's cleanser, and continues every day. I was slowly getting very good results with OS-01 before using your cleanser. Now I'm getting amazing results using both products. Long term skin damage from years of sun exposure is clearing up very rapidly. My skin is no longer inflamed or dry, and I actually see signs of aging being reversed. Inflammation, blemishes and wrinkles are disappearing. I am getting exponentially better results from your new cleanser than I have from deep pore scrubs or any other cleanser, with no downsides. Incredible. You've created a modern miracle.

William W.

I’ve had small spots of congestion on either side of my chin basically in my marionette wrinkles. I’ve had them for many years. Using your products (PREP and OS-01 FACE) together is actually making them dry up and disappear. My face feels soft, smooth and nourished. Pretty remarkable!!

Barbara R.

Wow! Small lines on my face are almost gone. Deeper lines( lip, mouth areas) much diminished.

Leslie F.

I was surprised to find a significant reduction in the visibility of my pores after one week of usage. After a week of use, I noticed an improvement in the texture of my skin, which was softer and smoother than normal. I also noticed marked minimization of the appearance of my pores.

Zachary M.

The cleanser is nice, feels good on my skin, and doesn’t cause irritation. I have eczema on parts of my face, and the cleanser didn’t cause it to flare up.

Haley P.

I like that the cleanser is gentle, yet effective. It doesn’t irritate my eyes at all and a small amount can work into a generous lather. The cleaner doesn’t overdry and appears to enhance the effects of the OneSkin Topical Supplement.

Bernard N.

I loved it! Felt it worked great to remove both sunscreen and makeup. Wasn’t drying at all and felt hydrating on its own. Friends said my skin looked fantastic. Felt like it reduced pore size too.

Sheila P.

My skin felt softer immediately after the first use. Even my boyfriend commented on my skin texture being improved. Loved the feel of the cleanser, the lack of scent, the foaming action!

Julia T.

My skin felt smoother and tighter after using the product, also less oily.

Robert H.

My skin overall feels smoother...the texture feels and looks better. My face felt super clean after using this, but not really tight or dry. So the cleansing properties were top notch. Mostly, I felt like the texture of my skin felt smoother and that was thoroughly impressive!

Krista M.

It feels like the lotion absorbs better and faster. Within a day or so I noticed my skin looking even more improved, like the cleanser amps up the strength of the lotion by quite a lot. I can tell it improves the effects of the topical lotion right away. It definitely seems to give more bang for the buck re: the topical lotion!

Corrie B.

I loved the way that it made my face feel less oily and prepared for the topical lotion.

Danny D.
  • Using PREP before OS-01 FACE doubles peptide penetration

    By comparing the amount of the OS-01 peptide present in the dermis layer after treatment with OS-01 FACE, our scientists found that the OS-01 peptide absorbs 2.2 times more effectively when skin is pre-cleansed with PREP versus not pre-cleansed at all.

  • Using PREP is scientifically proven to increase the hydration effects of OS-01 FACE

    By measuring the activity of a key gene associated with skin hydration (AQP3) before and after treatment in 46-year-old ex vivo skin, our scientists found that using PREP in combination with OS-01 FACE improved AQP3 activity by 40% versus using OS-01 FACE alone.

  • Sodium Grapeseed Amidopropyl PG-Dimonium Chloride Phosphate

    Breu Branco

    An antioxidant and exfoliating tree resin that neutralizes free radicals and is anti-inflammatory and anti-irritating.

  • Arnica Extract

    Arnica Extract

    An anti-inflammatory that stimulates microcirculation and moisturizes irritated skin.

  • Japanese Honeysuckle Extract

    Japanese Honeysuckle Extract

    A natural antioxidant with antibacterial and detoxifying properties.

  • Prickly Pear Extract

    Prickly Pear Extract

    Provides gentle exfoliation to remove dead skin cells while soothing irritated skin. Its high flavonoid content prevents oxidative stress and aids in sunburn recovery.

  • Niacinamide


    A conditioning agent that improves skin texture by promoting protein synthesis at the epidermal layer.

  • Sodium Grapeseed Amidopropyl PG-Dimonium Chloride Phosphate

    Sodium Grapeseed Amidopropyl PG-Dimonium Chloride Phosphate

    A multifunctional, natural triglyceride derived from grapeseed oil which is a 50x stronger antioxidant than Vitamin C or E.


average rating 4.8 out of 5
Based on 379 reviews
  • 5 Stars
    316 Reviews
  • 4 Stars
    42 Reviews
  • 3 Stars
    15 Reviews
  • 2 Stars
    4 Reviews
  • 1 Star
    2 Reviews
94% of reviewers would recommend this product to a friend
379 Reviews
Reviewed by Tara G.
Verified Buyer
I recommend this product
Rated 5 out of 5
Review posted

Excellent cleanser

I really love this body wash. It cleans well without stripping my skin, and actually leaves my skin feeling soft and ready for the OneSkin supplement. I use it from top to bottom twice daily.

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Reviewed by Stacey S.
Verified Buyer
OneSkin PREP Starter Kit (Bottle + Pouch)
I recommend this product
Rated 5 out of 5
Review posted

Feels clean...

Although can't say I've seen noticeable improvements in my skin yet, my face feels clean and fresh when used. I love the there is no extra scent, junk in the product.

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Reviewed by Piper B.
Verified Buyer
OneSkin PREP Starter Kit (Bottle + Pouch)
I recommend this product
Rated 5 out of 5
Review posted

Best ever!

As a licensed Esthetician I can say that this is the best cleanser ever.

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Reviewed by Jonathan M.
Verified Buyer
OneSkin PREP Starter Kit (Bottle + Pouch)
I recommend this product
Rated 5 out of 5
Review posted

Great product! Still new to it... like the results.

So far I'm quite happy with the results. A little bit goes a long way... the face prep and cream are a solid one two combo. Will keep using...

Was this helpful?
Reviewed by Ageliki
Verified Reviewer
I recommend this product
Rated 5 out of 5
Review posted


Amazing! I hope OneSkin comes out with PREP for the Body!!!

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