OS-01 FACE Topical Supplement, 50 mL

The first skin longevity treatment that extends skin health on the molecular level to address aging from within. Formulated for areas of your skin that are most exposed to environmental damage, including your face, hands, and neck.

  •  Developed by longevity scientists
  •  Safe and clean
  •  For all skin types
  •  Vegan & Cruelty-Free
  • Flagrance free Fragrance-Free

How to use

  • Apply 1-2 pumps onto skin as a daily essential moisturizer.
  • Where: Face, neck and hands.
  • When: Morning and evening after cleansing.

Ingredients

Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. *OS-01 Peptide.

FAQs

What is a Topical Supplement?
Just like you take vitamins and oral supplements every day for your general health and immunity, our Topical Supplement is a peptide moisturizer designed to improve your skin’s health and its subsequent appearance.
Topical Supplements are applied to specific areas of the skin to deliver targeted and visible skin repair results. Our Topical Supplements deliver OS-01, a proprietary peptide that extends your skin health, or your skinspan.
What is skinspan?
Skinspan refers to the length of time that your skin is healthy. For many, healthy skin presents as supple, smooth, and strong. Our mission is to extend your skinspan by optimizing skin health on a molecular level, increasing skin resilience and strength.
Unlike other skincare products that offer short-term solutions (and might even cause long-term damage), our Topical Supplements target the root causes of aging skin, including cellular damage and the accumulation of aged skin cells, for long-term, visible results.
How is OS-01 FACE formulated for use on areas exposed to the most damage (face, hands, and neck)?
The skin on the face, neck, décolletage, and hands is thinner and more delicate than the rest of the skin on the body. These areas of thin, delicate skin are the most likely to wrinkle, sag, lose elasticity, and show visible signs of premature aging.
Additionally, the delicate skin on the face, neck, décolletage, and hands are most exposed to (environmental) stressors like the sun, UV rays, dry air, cold and windy weather, air pollution, and other external sources that damage skin health and vitality, which are key contributors to skin’s appearance.
In order to combat environmental damages and premature aging of the facial skin, OS-01 FACE delivers an optimized concentration of the OS-01 peptide to reduce the skin’s biological age, support powerful cellular repair, and boost barrier function.

OS-01 FACE specifically benefits the more delicate skin of the face, neck, and hands by:

  • Sorting cellular repair and barrier function
  • Increasing epidermal thickness
  • Supporting collagen and elastin production, for stronger, firmer skin0
  • Supporting hyaluronic acid production, to boost hydration
  • Minimizing redness
  • Increasing skin silkiness and smoothness
We recommend applying OS-01 FACE to the most delicate and/or damaged/exposed areas of your skin, like the face, hands, and neck.
For all other areas, we recommend using OS-01 BODY.
Why is OS-01 FACE delivered topically?
Topical delivery ensures maximal penetration by the OS-01 peptide and efficacy to a specific area of skin. Through targeted topical application, the OS-01 FACE Topical Supplement is best able to deliver visible, noticeable improvements to the skin.
It’s also important to note that the science on the efficacy of ingestible skincare supplements is still out. Ingestible skincare supplements often degrade in stomach acid and fail to deliver any quantifiable, noticeable benefits to the skin. Combined with a healthy and balanced diet, Topical Supplements are your most effective tool to achieve faster, more visible improvements to the skin.
Is OS-01 FACE safe?
We’ve applied vigorous scientific rigor and exacting standards into formulating the safest, most effective Topical Supplements possible.
The Environmental Working Group (EWG) rates each skincare ingredient on a scale of 1-10, with a score of 1 being the safest and healthiest. OS-01 FACE received an average score of 1.02 and a weighted average of 1.04 on the EWG’s SkinDeep Cosmetics Database.
OS-O1 FACE was tested for human sensitization (RIPT - a clinical study to assess skin irritation) and various other toxicity tests. No adverse effects were found.
OS-01 FACE is clean, vegan, and cruelty free.
How should I integrate the OS-01 FACE into my current skincare routine?
At its core, our Topical Supplement is a peptide moisturizer, so we recommend applying it after cleansing and before sunscreen.
OS-01 FACE has not been shown to produce adverse reactions with other products and can be safely incorporated into your current routine.
Remember, it’s always best to patch test any new skincare product.
How does OS-01 FACE compare to retinol?
OS-01 FACE is safer and more effective than retinol.
Retinol targets the symptoms of aging by stimulating cell renewal which leads to peeling off the upper epidermal layers. However, retinol is often too harsh for many skin types, especially sensitive and drier skin. Negative side effects of retinol can include redness, irritation, dryness, flaking, and damage to the skin barrier which can increase skin sensitivity. When misused or overused, retinol can even compromise skin health in the long term. Skin thinning and a less resilient, weaker skin barrier are potential outcomes of such misuse.
OS-O1 FACE is a safer, highly efficacious topical skincare supplement that targets the root cause of skin aging at the molecular level by preventing the accumulation of damaged cells and increasing cellular repair capabilities. OS-01 FACE is more gentle than retinol - and our data supports similar or better effects in improving collagen and hyaluronic acid production.
Do you ship internationally?
Currently, we only ship to the U.S. and Canada.
We are working on adding international shipping options. Sign up for our newsletter for updates as we continue to expand.
What is the approximate shelf life of OS-01 FACE? How should it be stored?
OS-01 FACE has a shelf life of 24 months. Refer to the QR code on the back of your bottle for more details.
Is OS-01 FACE safe for pregnancy / breastfeeding?
We have rigorously tested our Topical Supplement for its safety on various skin types, however, we have not tested OS-01 FACE with pregnant or breastfeeding mothers.
We recommend pregnant and breastfeeding mothers show the ingredients list to a doctor or healthcare provider to confirm safety before use. As always, it’s best to consult with a medical professional before making lifestyle changes.
Is your packaging recyclable?
We are working diligently towards making our packaging 100% recyclable.
We offer free shipping labels so you can easily return empty packaging to us. To request a free shipping label please email us at support@oneskin.co.
Is OS-01 FACE sustainable / environmentally friendly / carbon neutral?
We are committed to environmental sustainability and protecting the plant. We constantly aim to reduce our environmental impact while creating cutting-edge, scientifically formulated Topical Supplements that improve the health, appearance, and vitality of the skin.
We partner with Zero Carbon to offset our carbon footprint to zero.
Stay in the loop about our sustainability goals, product news, and more by signing up for our newsletter here.
How long will my OS-01 Topical Supplement last?
The 50 mL bottle of OS-01 FACE will last approximately 2-3 months, when used as directed.
Have any more questions?
For our comprehensive FAQ list click here.

Healthy Skin
Starts Within

There’s more to aging than just the wrinkles you see.

OS-01 FACE addresses the root causes of aging so skin doesn’t just look younger, it actually functions like younger skin.

OS-01
Face

476 Reviews

The first skin longevity treatment that extends skin health on the molecular level to address aging from within.

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30 day money back guarantee We are confident you will be more than satisfied with our product so much so that we offer a 30-day money back guarantee on your first order. What this means is, you can request a refund at any point within 30 days of your first purchase of the product and get your money back with no questions asked. That's how much we believe in our product! We do want to note, based on feedback, most customers state results around the 6 week mark of continued use. [ + ] read more Try it risk-free!
We are currently low in stock. As such, we are temporarily only offering 60 day subsciptions. 30 day and 90 day subscriptions will be be available once stock is replenished. Once you receive your 50 mL bottle, you will be able to modify your subscription to 30 or 90 days.

476 Reviews

would recommend this product to a friend
Group 28 INCREASE EPIDERMAL THICKNESS
Fewer wrinkles and more protection against external stressors
Group 25 SUPPORT DNA DAMAGE REPAIR
Improves overall cell function
Group 30 PREVENT THE ACCUMULATION OF AGED CELLS
Helps maintain youthful and healthy skin
varinha-magica (1) IMPROVE COLLAGEN PRODUCTION
Increases skin firmness and strength
Group 31 IMPROVE SKIN TEXTURE AND SMOOTHNESS
Makes your skin feel and look great
water-tank INCREASE SKIN HYDRATION
Reduces water loss and supports production of hyaluronic acid

Elevate your skincare routine

Firmer, Smoother, and Stronger Skin.

Scientifically and Clinically backed

OS-01 Supporting Data

As we age, our skin becomes less efficient at clearing away damaged skin cells that weaken healthy cells around them. The accumulation of damaged cells reduces skin resilience and triggers wrinkles, dark spots, and loss of firmness. OS-01 reduces the accumulation of damaged cells so that skin stays healthier for longer. In a 12-week clinical study, OS-01 was shown to:

12 Weeks
Base Line
  • Improve Skin Barrier (Average Improvement + 15%)*
  • Improve Skin Elasticity (Shown in 90% of users)**
  • Improve Skin Evenness,
    Radiance, Pores, & Firmness (Shown in 95.5% of users)**
  • Reduce Appearance of Fine Lines & Wrinkles (Shown in 87% of users)
  • Improve Skin Smoothness
    & Overall Appearance (Shown in 100% of users)

*Instrumental Evaluation - Vapometer analysis

*Double-blind expert clinical grader evaluation

Active Ingredients

Seven key ingredients that work with OS-01 to boost moisture, reinforce barrier function, and diminish skin stress



Reviews

average rating 4.7 out of 5
Based on 479 reviews
  • 5 Stars
    372 Reviews
  • 4 Stars
    84 Reviews
  • 3 Stars
    23 Reviews
  • 2 Stars
    0 Reviews
  • 1 Star
    0 Reviews
96% of reviewers would recommend this product to a friend
Quality
Rated 4 out of 5
Feel good factor
Rated 4 out of 5
Customer photos and videos
Review posted
Reviewed by Emily C.
Verified Buyer
Age Range
35 - 44
Gender
F
My results
  • Smoother skin
  • Reduced lines and wrinkles
Skin type
Sensitive
Rated 5 out of 5

So far so good

It’s been a few weeks now and I can see a slight difference in my eye area and my 11s in particular. It took some time to figure out where I like it in my routine but now I’m really enjoying it. I broke out for the first few days but now I’m clear and loving it.

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I recommend this product
Quality
Rated 4 out of 5
Feel good factor
Rated 5 out of 5
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Review posted
Reviewed by Elaine R.
Verified Buyer
Age Range
55 - 64
Gender
F
My results
  • Smoother skin
  • Glowing skin
Skin type
Normal
Rated 5 out of 5

Love it!!

I’ve been using os-01 for about 2 weeks. I can already see a difference. My skin looks and feels smoother and brighter

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I recommend this product
Quality
Rated 5 out of 5
Feel good factor
Rated 5 out of 5
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Review posted
Reviewed by Suzanne B.
Verified Buyer
Age Range
45 - 54
Gender
F
My results
  • Firmer skin
  • Smoother skin
  • Reduced lines and wrinkles
  • Glowing skin
Skin type
Aging
Rated 5 out of 5

OS-01 FACE Topical Supplement

I am 53, and my sensitive skin loves this lotion. I apply to slightly damp skin in AM and PM and it absorbs completely, leaving my skin feeling cared for and hydrated. It’s as if I have nothing on my skin and it can breathe. Under eye area is already firmer in only 1 week!

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I recommend this product
Quality
Rated 5 out of 5
Feel good factor
Rated 5 out of 5
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Review posted
Reviewed by Howard F.
Verified Buyer
Age Range
55 - 64
Gender
M
My results
  • Smoother skin
  • Reduced lines and wrinkles
Skin type
Aging
Rated 5 out of 5

3rd party confirmation or results

It’s hard to determine the exact contribution of OS-01 to my overall face appearance. However, anyone that has children, especially teenagers, knows that they can be very critical. When my teenager said “Dad, your skin looks really good. Whatever you’ve been doing, keep doing it.” That “whatever” would be daily use of OS-01. The science is solid and the results are noticeable. I’m very pleased that it doesn’t leave my face feeling greasy. My girlfriend, who is very much into cosmetics, applied OS-01 to her face the first time about a year ago. Her immediate response was, “this lotion is really nice, will you buy me some?” ! I’m a 55 y.o. male that hasn’t always been good to my skins ie. too much sun and alcohol and not enough sleep. I am somewhat familiar with the science behind the OS-01 product. As an Organic Chemist that currently practicing in the healthcare environment, I anticipated the development of this product and have used it for a over a year. Needless to say, I am very happy with the product and the customer service that’s supports it. Example: I moved and therefore, changed shipping address. This led to a shipment being sent to the old address. When I contacted customer service about this issue, there were no questions. They immediately sent a new bottle to my new address and even sent the Mother’s Day 15ml gift that I had not asked for. Kudos customer service team!!! I really appreciate you! Peace and health,

Howard

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I recommend this product
Quality
Rated 5 out of 5
Feel good factor
Rated 5 out of 5
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Review posted
Reviewed by Laura M.
Verified Buyer
Age Range
55 - 64
Gender
F
My results
  • Smoother skin
  • Firmer skin
  • Reduced lines and wrinkles
  • Glowing skin
Skin type
Aging
Rated 5 out of 5

It’s the real deal!

It actually works like OS says. It makes your skin thicker, smoother ,more even toned and reduces fine lines and wrinkles. My skin feels healthier all over. I highly recommend it.

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I recommend this product
Quality
Rated 5 out of 5
Feel good factor
Rated 5 out of 5
Was this helpful?

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