OS-01 Topical Supplement

The first topical supplement of its kind designed to extend your skinspan by improving skin health and skin strength. Our proprietary peptide, OS-01, has been shown to rejuvenate your skin on a molecular level and effectively treat the negative implications of aging.

  • Scientifically developed by a team of female PhDs
  • Safe beauty (meets the strictest criteria for transparency and health)
  • Vegan and cruelty free
  • Safe for all skin types (because we all age!)

How to use

  • Apply 1-2 pumps onto skin as a daily moisturizer.
  • Where: Face, neck and hands.
  • When: Morning and evening after cleansing.

Ingredients

Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. *OS-01 Peptide.

FAQs

What is a topical supplement?
Just like you take vitamins everyday for general health and immunity, our topical supplement delivers OS-01, a proprietary peptide that extends your skin health (aka your skinspan). Unlike other skincare products that offer short-term solutions (and might even cause long-term damage), we target one of the root causes of aging on the molecular level for long-term results.
Why is OS-01 delivered topically?
This allows for our peptide to be applied to a specific area of skin to maximize penetration and efficacy. In the lab, we measure how OS-01 affects both the dermis and epidermis specifically. More importantly, ingestible supplements often degrade in stomach acid and therefore have no direct effect on the skin, but when applied topically there can be real (and measurable) changes.
Is your topical supplement safe?
We’ve applied the same scientific rigor into formulating a safe product as we did for effectiveness. EWG rates ingredients on a scale of 1-10, with a score of 1 being the safest and healthiest. OS-01 received an average score of 1.02 and a weighted average of 1.04. Our supplement was tested for human sensitization (RIPT - a clinical study to assess skin irritation) and various other toxicity tests, and no adverse effects were found. Note: score of 1.02 reflects our weighted average and 1.04 reflect our average.
How should I integrate the topical supplement into my current skincare routine?
At its core, our topical skin supplement is a moisturizer, so we recommend applying the product after cleansing and before applying a sunscreen. The good news is that our product has not been shown to have adverse reactions with other products, so you can safely incorporate it into your current routine without any additional changes.
How does your topical supplement compare to retinol?
We’re safer and more effective. Retinol targets the symptoms of aging and, when misused or overused, can cause long-term damage to skin by the constant peeling off of epidermal layers. In contrast, OS-O1 targets the root cause of skin aging at the molecular level by preventing the accumulation of senescent cells.
Do you ship internationally?
Unfortunately, we currently only ship to the US, but we’re actively working to change this. Sign up for our newsletter to stay in the know for updates as we continue to expand.
What is the approximate shelf life for your topical supplement ? How should it be stored?
Our topical supplement has a shelf life of 16 months. Refer to the QR code on the back of your bottle for more details.
Is your topical supplement safe for pregnancy / breastfeeding?
Our topical supplement is as safe and effective as can be. We have rigorously tested it’s safety on various skin types, however, we have not tested it on pregnant or breastfeeding mothers. Because of this, we recommend pregnant and breastfeeding mothers show our ingredients list to your doctor or health care provider to confirm its safety before using.
Is your packaging recyclable?
We are working diligently towards making our packaging 100% recyclable. Currently, once you have finished using our product, you can request a free shipping label to return the empty packaging to us. Also, we have partnered with Zero Carbon to offset our carbon footprint to zero! Stay tuned for more updates on our sustainability goals!
What is skinspan?
Skinspan refers t o the length of time that your skin is healthy. Our mission is to extend your skinspan by optimizing skin health on a molecular level and increasing skin strength.
How long will my OS-01 Topical Supplement last?
We estimate the 50 ml bottle of our Topical Supplement will last approximately 2-3 months when used as directed.

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average rating 4.8 out of 5
  • 5 Stars
    102 Reviews
  • 4 Stars
    25 Reviews
  • 3 Stars
    7 Reviews
  • 2 Stars
  • 1 Star
97% of reviewers would recommend this product to a friend
Group 28 INCREASE EPIDERMAL THICKNESS
Fewer wrinkles and more protection against external stressors
Group 25 SUPPORT DNA DAMAGE REPAIR
Improves overall cell function
Group 30 PREVENT THE ACCUMULATION OF AGED CELLS
Helps maintain youthful and healthy skin
varinha-magica (1) IMPROVE COLLAGEN PRODUCTION
Increases skin firmness and strength
Group 31 IMPROVE SKIN TEXTURE AND SMOOTHNESS
Makes your skin feel and look great
water-tank INCREASE SKIN HYDRATION
Reduces water loss and supports production of hyaluronic acid

Elevate your skincare routine

Firmer, Smoother, and Stronger Skin.

Scientifically and Clinically backed

OS-01 Supporting Data

We performed a 12-week clinical study to validate and quantify the impact of OS-01 in improving skin health. Our results showed that OS-01 is clinically proven to strengthen the skin barrier in addition to providing remarkable visual benefits.

12 Weeks
Base Line
  • Improved Skin Barrier (Average Improvement + 15%)*
  • Improved Skin Elasticity (Shown in 90% of users)**
  • Improved Skin Evenness,
    Radiance, Pores, & Firmness (Shown in 95.5% of users)**
  • Less Wrinkles (Shown in 87% of users)
  • Improved Skin Smoothness
    & Overall Appearance (Shown in 100% of users)

*Instrumental Evaluation - Vapometer analysis

*Double-blind expert clinical grader evaluation

Proprietary and high quality

Active Ingredients

Reviews

average rating 4.8 out of 5
Based on 8 reviews
  • 5 Stars
    7 Reviews
  • 4 Stars
    0 Reviews
  • 3 Stars
    1 Review
  • 2 Stars
    0 Reviews
  • 1 Star
    0 Reviews
88% of reviewers would recommend this product to a friend
Review posted
Reviewed by Joan A.
Verified Buyer
Rated 5 out of 5

Smoother skin

I used One Skin for about two months and didn't think it was doing anything so I stopped using it for a few weeks. That's when I realized that it really WAS making my skin smoother and firmer. So I started using it again and am very happy with the results. Just started my second bottle. I find that one pump is sufficient because my skin is still somewhat oily in some areas.

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Reviewed by Barbara D.
Verified Buyer
Rated 5 out of 5

ONE SKIN RESULTS

i have been using ONE SKIN for 61/2 months. many people have said my skin looks incredible. i told them about you. i,m very happy with what i see. thank you all.

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Reviewed by Sharon Z.
Verified Buyer
Rated 5 out of 5

Fantastic!

OneSkin has definitely given my skin a freshness and glow. I give it 5 stars for its effectiveness and easy use.

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Reviewed by Elta M.
Verified Buyer
Rated 5 out of 5

Noticed the difference already!

My skin has become noticeably softer and less dry and irritated. The one step routine is so much easier to maintain than all the convoluted multi-step ones I've tried before that just sat on my counter. Looking forward to more changes in the coming months.

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Reviewed by Jill S.
Verified Buyer
Rated 5 out of 5

Pleased with results

I am 44 years old and have invested in skincare since my early 20’s. In the past few years my skin has aged and changed dramatically. I have tried many high end products to address these signs of aging, but been frustrated by the lack of results. OS-01 is the first product that I can say I saw positive results in my skin almost immediately. My skin tone, texture, fine lines, and pores are all greatly improved!

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