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OS-01 LIP SHIELD SPF 15+

4.5
4.5 out of 5
4.5 (333)

12 mL / 0.41 fl oz

OS-01 LIP SHIELD SPF 15+

Mineral Sunscreen

4.5
4.5 out of 5
4.5 (333)

12 mL / 0.41 fl oz

Instant hydration and UV defense for vulnerable lips, powered by the OS-01 Peptide™ to support long-term health and resilience.



  • Protects against 3 main drivers of lip skin aging

  • Hydrating, smooth, non-sticky mineral SPF protection

  • Available in untinted or semi-sheer Bare Blush to enhance natural lip tone

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  • Accepted National Eczema Association logo
  • Leaping bunny certified logo

THE LIP TRIFECTA

Three benefits. Two seconds. OneSkin.

Cellular support, UV protection, and instant hydration—all in a semi-sheer tint you’ll want to wear all day.

OneSkin

Formulated with ingredients designed to target the main drivers of aging in lip skin.


OS-01 Peptide™

Engineered to address a leading driver of visible aging


Non-nano zinc oxide
Protects against UV aging and damage with mineral broad spectrum SPF 15+ defense


6 antioxidants
Combat oxidative aging from environmental stress

OneSkin

Formulated with ingredients designed to target the main drivers of aging in lip skin.


OS-01 Peptide™

Engineered to address a leading driver of visible aging


Non-nano zinc oxide
Protects against UV aging and damage with mineral broad spectrum SPF 15+ defense


6 antioxidants
Combat oxidative aging from environmental stress

5-star reviews

See why customers love OS-01 LIP SHIELD SPF 15+

“My lips appear plumper and deeper in color in an incredibly healthy and youthful appearance. I have tried high end and low end brands and nothing compares to the efficacy of this product.” – Caroline W.

"My lips have constantly felt softer. And I also had a special case because I had an eczema patch on my lips before I started using this product, and I was worried it would make it worse but it actually made it better! My eczema patch cleared up after a couple weeks of use. Huge fan of this product overall.” – Victoria Z.

“This definitely helped my chronically dry and chapped lips. I would make this my go to moving forward.” – Adam P.

5-star reviews

See why customers love OS-01 LIP SHIELD SPF 15+

“My lips appear plumper and deeper in color in an incredibly healthy and youthful appearance. I have tried high end and low end brands and nothing compares to the efficacy of this product.” – Caroline W.

"My lips have constantly felt softer. And I also had a special case because I had an eczema patch on my lips before I started using this product, and I was worried it would make it worse but it actually made it better! My eczema patch cleared up after a couple weeks of use. Huge fan of this product overall.” – Victoria Z.

“This definitely helped my chronically dry and chapped lips. I would make this my go to moving forward.” – Adam P.

CONSUMER PERCEPTION DATA

Real results that speak volumes

92
agree it delivers immediate hydration and moisture 01

88
agree it makes their lips feel soothed and protected 01

84
agree their lips felt nourished after 2 weeks 01

78
agree it provides long-lasting hydration and moisture 01

CONSUMER PERCEPTION DATA

Real results that speak volumes

92
agree it delivers immediate hydration and moisture 01

88
agree it makes their lips feel soothed and protected 01

84
agree their lips felt nourished after 2 weeks 01

78
agree it provides long-lasting hydration and moisture 01

How it works

Powered by the OS-01 Senescence Blocking Peptide™

Born from over a decade of longevity science, OS-01 is engineered to address a key driver of visible skin aging, supporting meaningful improvements in skin health today and over time to future-proof skin.

OS-01 LIP SHIELD SPF 15+

4.5
Rated 4.5 out of 5 stars
Based on 333 reviews
Total 5 star reviews: 259 Total 4 star reviews: 35 Total 3 star reviews: 14 Total 2 star reviews: 12 Total 1 star reviews: 13
88%would recommend these products
333 reviews
  • BL
    Barbara L.
    Verified Buyer
    Reviewing
    OS-01 LIP SHIELD SPF 15+
    I recommend this product
    Rated 5 out of 5 stars
    3 minutes ago
    Lip treatment

    Lip SPF 15+ what a lovely lip treatment. This product is quite nourishing. The cooling metal applicator blends the creamy product as it melts into your lips.

    Makes my lips very soft and supple.

    I definitely recommend this lip treatment.

  • PW
    Patricia W.
    Verified Buyer
    Reviewing
    OS-01 LIP SHIELD SPF 15+
    I recommend this product
    Rated 5 out of 5 stars
    4 hours ago
    Perfect for outdoor coverage

    I use this during my workouts in the sun, provides great benefits without being gummy or anything fake in it.

  • MW
    Maria w.
    Verified Buyer
    Reviewing
    OS-01 LIP SHIELD SPF 15+
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    Great!

    I love this so far

  • SM
    Susan M.
    Verified Buyer
    Reviewing
    OS-01 LIP SHIELD SPF 15+
    I recommend this product
    Rated 4 out of 5 stars
    Yesterday
    First time trying

    I like this product and feel some beginning of lip plumping so I am using 1x daily for this purpose, however, I feel like it somehow dries my lips unlike my other peptide lip products - so I use this plus my regular hydrating lip stuff from another brand throughout the day.

    OneSkin
    Yesterday

    Hi Susan! Thank you so much for your wonderful 4-star feedback about OS-01 LIP SHIELD SPF 15+! We're absolutely thrilled to hear that you're loving the product and already experiencing some exciting lip plumping benefits after just starting to use it - that kind of positive response to our science-backed formula really means the world to all of us at OneSkin!

    We love that you're finding OS-01 LIP SHIELD delivers those amazing plumping results that you're looking for! Your experience with the early signs of plumping benefits really shows how our carefully crafted OS-01 Peptide is working to support your lip health and appearance. It's so wonderful that you're incorporating it into your daily routine specifically for those plumping benefits - that targeted approach really demonstrates how thoughtfully you're building your lip care routine.

    Your honest perspective about finding it works differently than your other peptide lip products really helps us understand how our formula fits into your overall lip care needs! We completely understand that everyone's lips respond uniquely to different formulations, and the fact that you've found a great way to combine OS-01 LIP SHIELD with your regular hydrating products shows such a smart approach to getting the best results for your specific needs.

    How exciting that you're already seeing those promising plumping benefits while building a routine that works perfectly for you! The fact that you're using it daily for that specific purpose while supplementing with additional hydration really demonstrates how you're maximizing the unique benefits of our peptide formula alongside your other favorite products.

    Stories like yours about experiencing early plumping results while thoughtfully combining products to meet your lip needs are exactly why we're so passionate about what we do! Your approach to getting the best of both worlds with our peptide benefits plus your preferred hydration really shows the wonderful care you're taking with your lip routine.

    Thank you for taking the time to share such valuable feedback about your OS-01 LIP SHIELD experience - your 4-star review truly means so much to us!

  • VR
    Valerie R.
    Verified Buyer
    Reviewing
    OS-01 LIP SPF, Recurring
    I recommend this product
    Rated 5 out of 5 stars
    2 days ago
    lovely natural color

    easy to apply, comforting to know my lips are protected too

All ingredients

Active ingredients: Zinc Oxide 5.5%

Inactive Ingredients: Simmondsia, Chinensis (Jojoba) Seed Oil, Ethylene/Propylene/Styrene Copolymer, Ethylhexyl Palmitate, Butyloctyl Salicylate, Caprylic/Capric Triglyceride, Water (Aqua), Garcinia Indica Seed Butter, Tocopheryl Acetate, Butylene/Ethylene/Styrene Copolymer, Glyceryl Oleate, Glyceryl Dioleate, Glycerin, Oleic Acid, Tribehenin, Sorbitan Isostearate, Palmitoyl Tripeptide-1, Dipalmitoyl Hydroxyproline, Trihydroxystearin, Sodium Hyaluronate, Glucomannan, Tetrahexyldecyl Ascorbate, Bisabolol, Decapeptide-52*, Ethylhexylglycerin, Caprylyl/Capryl Glucoside, Propanediol, Ectoin, Centella Asiatica Extract, Hippophae Rhamnoides Oil, Helianthus Annuus (Sunflower) Seed Oil, Copernicia Cerifera (Carnauba) Wax, Tocopherol, Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate, Polyhydroxystearic Acid, Polyglyceryl-3 Polyricinoleate, Isostearic acid, Lecithin, Beta-Sitosterol, Squalene, Lactic Acid, Palmitic acid. *OS-01 Peptide

Drug Facts

Active Ingredients: Zinc Oxide 5.5% …………Purpose: Sunscreen

Uses

  • Helps prevent sunburn
  • If used as directed with other sun protection measures (see directions), decreases the risk of skin cancer and early skin aging caused by the sun.

Warnings

  • For external use only.
  • Do not use on damaged or broken skin.
  • Stop use and ask a doctor if rash occurs.
  • Keep out of reach of children.

All ingredients

Active ingredients: Zinc Oxide 5.5%

Inactive ingredients: Simmondsia Chinensis (Jojoba) Seed Oil, Ethylene/Propylene/Styrene Copolymer, Ethylhexyl Palmitate, Butyloctyl Salicylate, Caprylic/Capric Triglyceride, Water (Aqua), Garcinia Indica Seed Butter, Tocopheryl Acetate, Butylene/Ethylene/Styrene Copolymer, Glyceryl Oleate, Glyceryl Dioleate, Glycerin, Oleic Acid, Tribehenin, Sorbitan Isostearate, Palmitoyl Tripeptide-1, Dipalmitoyl Hydroxyproline, Trihydroxystearin, Sodium Hyaluronate, Glucomannan, Tetrahexyldecyl Ascorbate, Bisabolol, Decapeptide-52*, Ethylhexylglycerin, Caprylyl/Capryl Glucoside, Propanediol, Ectoin, Centella Asiatica Extract, Hippophae rhamnoides (Sea Buckthorn) Oil, Helianthus Annuus (Sunflower) Seed Oil, Copernicia cerifera (Carnauba) Wax, Tocopherol, Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate, Polyhydroxystearic Acid, Polyglyceryl-3 Polyricinoleate, Isostearic Acid, Lecithin, Lactic Acid, Octyldodecanol, Sorbitan Oleate, Alumina, Magnesium Oxide, Palmitic Acid, Iron oxides (CI 77491, CI 77492, CI 77499), Titanium Dioxide (CI 77891), Red 33 Lake (CI 17200), Red 7 Lake (CI 15850).

Drug Facts

Active Ingredients: Zinc Oxide 5.5% …………Purpose: Sunscreen

Uses

  • Helps prevent sunburn
  • If used as directed with other sun protection measures (see directions), decreases the risk of skin cancer and early skin aging caused by the sun.

Warnings

  • For external use only.
  • Do not use on damaged or broken skin.
  • Stop use and ask a doctor if rash occurs.
  • Keep out of reach of children.

Citations

01 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims.
02 Zonari, A.,et al.Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models.npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1
03 Zonari A.,et al.Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation.J Cosmet Dermatol.2024; 23: 2135-2144. doi:10.1111/jocd.16242