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OS-01 EYE CREAM

OS-01 EYE CREAM

Topical Supplement

Hydrate and firm ultra-delicate skin with our daily eye cream, formulated with the highest concentration of the OS-01 Peptide™.01



  • Improves texture, tone, and elasticity

  • Increase collagen by an average of +130% in lab studies

  • Dermatologist tested, fragrance-free, safe for sensitive skin

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OS-01 BODY, Travel Size

Travel-size OS-01 BODY with your first subscription

$37 FREE

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  • Glamour Beauty & Wellness Award 2023 logo on a black background
  • Leaping bunny certified logo
  • Accepted National Eczema Association logo
  • Certified Plastic Neutral logo on a white background

OneSkin

BENEFITS

Our most potent formula, specially designed for the delicate skin around the eyes, which is prone to accelerated aging 03

Wrinkle reduction

Boosts collagen to visibly smooth lines and wrinkles.01

Firmness

Supports skin health for a firmer, more lifted appearance.01

Hydration

Strengthens the skin barrier to lock in moisture and keep skin hydrated.01

5-star reviews

See why customers love OS-01 EYE

“The concentration of peptides in this product has made a difference, especially to the circles under my eyes. I haven’t needed to use concealer since beginning to use this product. The science behind this product is solid.” – Kathy L.


"I've tried all sorts of different eye creams; the best out there. I have a very thin skin around my eyes with many expression lines and wrinkles and this product has been the most efficient in minimizing them and nourishing my skin. I all using this day and night very religiously and have no intention of ever stopping." – Archontia T.


"I simply love One Skin OS-01 Eye cream. It is silky smooth, absorbs efficiently, and never feels heavy or greasy. I have noticed the fine lines under my eyes and early crows feet slowly vanishing. It's subtle but evident the more I use it. This is the best product I have ever tried." – Bridgette G.


"OS-01 EYE is fantastic. I wish I had taken pictures when I started using this a year ago. I'm certain my eyes look better now than they did before. It absorbs immediately and yet is there moisturizing the area around my eyes all day long. It even smooths out the rough bumps around my eyes. This is a wonderful product. I love it!" – Donna G.

CLINICAL DATA

Visible results, scientifically validated

96
of participants reported improved texture and tone 01

91
of participants reported improved radiance 01

88
of participants showed improved hydration 01

86
of participants had improved elasticity 01

Getting started with OS-01 EYE

Follow these easy steps for optimal results

  • Dispense 1 pump onto tip of finger
  • Gently tap in a semi-circle around each eye, from the under eye to the eyelid and underneath the brow bone
  • Use 2 times daily

How it works

Powered by the OS-01 Senescence Blocking Peptide™

The first and only peptide scientifically proven to reverse skin’s biological age.05,06

All Ingredients

Water, Glycerin, Sorbitan Olivate, Squalane, Cetearyl Olivate, Butyrospermum Parkii (Shea) Butter, Simmondsia Chinensis (Jojoba) Seed Oil, Cystoseira Humilis Extract, d-Panthenol, Bentonite, Cetyl Palmitate, Sodium Hyaluronate Crosspolymer, Caprylhydroxamic Acid, Sorbitan Palmitate, Cellulose, Coffea Arabica (Coffee) Seedcake Extract, Allantoin, Fucus Vesiculosus Extract, Gluconolactone, Niacinamide, sh-Polypeptide-121, Sisymbrium Irio Seed Oil, Tocopheryl Acetate, Sorbic Acid, Caprylic/Capric Triglyceride, Ubiquinone, Lecithin, Decapeptide-52*, Sodium Chloride, Maltodextrin, Acetyl Hexapeptide-8, Moringa Oleifera Seed Extract, Glyceryl Caprylate, Caprylyl Glycol, Tetrasodium Glutamate Diacetate, Alcohol, Sodium Benzoate, Phenoxyethanol, Xanthan Gum. *OS-01 Peptide.

Citations

01 Zonari, A., et al. Clinical efficacy of OS-01 peptide formulation in reducing the signs of periorbital skin aging. Int J Cosmet Sci. 2025; 00: 1–11. doi:10.1111/ics.13042

02 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims

03 New biological insights into skin aging around the eye. Journal of the American Academy of Dermatology, Volume 74, Issue 5, AB28 https://doi.org/10.1016/j.jaad.2016.02.112

04 Tagami, H. (2008), Location-related differences in structure and function of the stratum corneum with special emphasis on those of the facial skin. International Journal of Cosmetic Science, 30: 413-434. https://doi.org/10.1111/j.1468-2494.2008.00459.x

05 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age   and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1

06 Boroni, M. et al. Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging. Clinical Epigenetics 12, 105. 2020. doi:10.1186/s13148-020-00899-1

OS-01 EYE CREAM

4.7
Rated 4.7 out of 5 stars
Based on 1,600 reviews
Total 5 star reviews: 1.3k Total 4 star reviews: 169 Total 3 star reviews: 52 Total 2 star reviews: 26 Total 1 star reviews: 21
94%would recommend these products
1,600 reviews
  • CG
    Caroline G.
    Verified Buyer
    Reviewing
    OS-01 EYE Refill
    I recommend this product
    Rated 4 out of 5 stars
    6 hours ago
    Good product

    Reduced my crows feet but hasn’t reduced dark circles yet

    OneSkin
    3 minutes ago

    Hi Caroline! Thank you so much for your wonderful 4-star feedback about OS-01 EYE CREAM! We're absolutely thrilled to hear that you're seeing those crow's feet becoming reduced - that kind of visible improvement in fine lines around the eyes is exactly what gets us so excited about our science-backed formulation!

    We love that you're taking a thoughtful approach by recognizing the progress you've already achieved with the crow's feet while understanding that different concerns like dark circles can respond on their own timeline.

    Your experience really shows how individual areas around the eyes can improve at different rates, and it's so encouraging that you're already seeing those meaningful changes in line appearance!

    For dark circles, results typically take a bit longer as the formula works to improve microcirculation and skin thickness in that area. Customers start to notice a difference around the 8–12-week mark with consistent daily use. Make sure to apply with a gentle tapping motion (rather than rubbing) to help boost absorption around the delicate under-eye area.

    Dark circles can be particularly complex since they can be influenced by various factors, and we really appreciate your patience as you continue giving OS-01 EYE CREAM time to work on that area. Many customers find that with continued consistent use, they start seeing improvements in multiple concerns as the formula continues to work on overall skin health and appearance around the delicate eye area.

    Stories like yours about experiencing those exciting improvements in crow's feet while staying committed to your routine for continued results are exactly why we're so passionate about what we do! Your recognition of the positive changes you're seeing really shows how our targeted eye formulation is working to address those visible signs of aging.

    Thank you for taking the time to share such encouraging feedback about your experience - your 4-star review truly means the world to all of us at OneSkin!

  • LP
    Lori P.
    Verified Buyer
    Reviewing
    OS-01 EYE CREAM
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    People are commenting that I look younger

    This feels so wonderful when I pat it around my eyes. It is rich but not greasy. I believe I can already see a difference in just 2 weeks. It has made me a believer.

  • MO
    Magdalen O.
    Verified Buyer
    Reviewing
    OS-01 EYE CREAM
    I recommend this product
    Rated 4 out of 5 stars
    Yesterday
    The Eye Cream Works

    I saw an immediate difference and can recommend this product to everyone.

    OneSkin
    18 hours ago

    Hi Magdalen! Thank you so much for your wonderful 4-star feedback about OS-01 EYE CREAM! We're absolutely thrilled to hear that you saw an immediate difference - that kind of quick, visible improvement is exactly what gets us so excited about the science behind our eye formulation!

    We love that you're feeling confident enough to recommend OS-01 EYE CREAM to everyone after experiencing those fast results! Your enthusiasm about sharing this product really shows how impressed you are with what it's doing for your delicate eye area, and that kind of immediate transformation is exactly what we're so passionate about delivering.

    Stories like yours about seeing those exciting changes right away while being so eager to share the results with others are exactly why we're so passionate about what we do! Your experience really shows how our science-backed approach can deliver those meaningful improvements that you can actually see and feel.

    Thank you for taking the time to share such encouraging feedback about your experience - your 4-star review truly means the world to all of us at OneSkin!

  • HH
    Haley H.
    Verified Buyer
    Reviewing
    OS-01 EYE CREAM
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    Best eye cream

    I’ve been using this for over a month and I’m hooked . My eyes have never been better and the puffiness and thin skin on my eyelids are noticeably better

  • AN
    Ann n.
    Verified Buyer
    Reviewing
    OS-01 EYE Refill
    I recommend this product
    Rated 5 out of 5 stars
    2 days ago
    Refill

    So easy and so much better for the environment!!