OS-01 BODY MOISTURIZER
250 mL / 8.45 fl oz
OS-01 BODY MOISTURIZER
Topical Supplement
250 mL / 8.45 fl oz
Revive thin, crepey skin with our daily body moisturizer, powered by the OS-01 PeptideTM and OneSkin Longevity ScienceTM.01
- Improves skin texture, appearance, and hydration
- Strengthens the skin barrier by up to +41%
- Dermatologist tested, fragrance-free, safe for sensitive skin
- Exclusive early access to new products
- Earn 2x points on all recurring orders
- Easily change, skip or cancel anytime
LIMITED TIME OFFER
Travel-size OS-01 FACE with your first subscription
✭ You’re earning 89 points with OneSkin Loyalty Program ✭
Free shipping on orders over
Try it risk-free! 45 day money back guarantee.
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BENEFITS
Nourishing body moisturizer and targeted treatment for thin, crepey skin
Smooth texture
Improves the root cause of crepey skin by supporting epidermal thickness for a firmer look and feel.01
Deep hydration
Replenishes and locks in hydration to keep skin soft, plump, and nourished.01
Barrier support
Fortifies the skin barrier to protect against daily stressors and moisture loss.01
5-STAR REVIEWS
See why customers love OS-01 BODY
“The skin on my legs was starting to look older, dry and crepey at 46. Now it is plump and youthful like it was 10 years ago after only a few weeks.” – Jen A.
"The One skin, OS-O1 Body, has been a game changer, within a few weeks I saw a remarkable difference in the quality of my skin, and my skin's appearance continues to improve with daily application. It now has a tighter, less dry look and the texture has almost returned to my premenopause condition..more moist and fresh in appearance. Science is everything, and One Skin has got the science spot on." – Tia T.
"I love this body lotion. My crepey skin is transforming. I wish I had taken pictures before I started using it but I have tried so many different products with no results that I didn’t have much confidence that this one would be any different. Boy was I wrong. I’m hoping that it will eventually get rid of all my dark spots on my skin. I will be a forever customer..."– Myra P.
The proof is in the pictures
CLINICAL DATA
Visible results, scientifically validated
93
of participants reported improved hydration 01
70
of participants reported improved appearance 01
70
of participants reported improved texture 01
41
Improvement in skin barrier function was measured 01
5 active ingredients complement the OS-01 peptide
Getting started with OS-01 BODY
Follow these easy steps for optimal results
- Apply to arms, legs, chest, back, and stomach
- Massage until absorbed
- Use 2 times daily
How it works
Powered by the OS-01 Senescence Blocking Peptide™
The first and only peptide scientifically proven to reverse skin’s biological age.02,03
All Ingredients
Water, Glycerin, Limnanthes Alba (Meadowfoam) Seed Oil, Sorbitan Olivate, Avena Sativa (Oat) Kernel Oil, Squalane, Prunus Domestica Seed Oil, Saccharide Isomerate, Cetearyl Olivate, d-Panthenol, Mangifera Indica (Mango) Seed Butter, Tremella Fuciformis (Mushroom) Extract, Tocopheryl acetate, Decapeptide-52*, Allantoin, Asiaticoside, Centella Asiatica Extract, Sodium Hyaluronate Crosspolymer, Ceramide NP, Anadenanthera Colubrina Bark Extract, Lepidium Sativum Sprout Extract, Genistein, Niacinamide, Glycerol, Bentonite, Cetyl Palmitate, Sorbitan Palmitate, Lecithin, Xanthan Gum, Polyglyceryl-10 Laurate, Polyglyceryl-6 Oleate, Sorbitan Oleate, Glyceryl Caprylate, Polysorbate 80, Alcohol, Caprylyl Glycol, Sorbic Acid, Citric Acid, Sodium Citrate, Pentylene Glycol, Potassium Sorbate, Ethylhexylglycerin, Caprylhydroxamic Acid, Tetrasodium Glutamate Diacetate, Phenoxyethanol. *OS-01 Peptide
Citations
01Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims
02Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1
03Boroni, M. et al. Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging. Clinical Epigenetics 12, 105. 2020. doi:10.1186/s13148-020-00899-1
OS-01 BODY MOISTURIZER
- JSJohnnie S.Verified BuyerReviewingOS-01 BODYI recommend this productRated 5 out of 5 stars42 minutes agoBest body moisturizer I've ever used
This is the only body moisturizer I’ve EVER used that truly delivers a deep and lasting moisure barrier
- JHJoan H.Verified BuyerReviewingOS-01 BODYI recommend this productRated 5 out of 5 stars3 hours agoBody Lotion
Gentle, smooth easy to use lotion.
- EBEileen B.Verified BuyerReviewingOS-01 BODYI recommend this productRated 5 out of 5 stars16 hours agoBody lotion
This body lotion is amazing. It has really hydrated my skin.
- MGMandie G.Verified BuyerReviewingOS-01 BODYI recommend this productRated 5 out of 5 stars17 hours agoGreat lotion!
Love it!
- HThilary t.Verified BuyerReviewingOS-01 BODY MOISTURIZERI do not recommend this productRated 2 out of 5 stars19 hours agolotion
I do not find that it is working to diminish the crepey skin I have on my legs and arms. I am very athletic but do have a little crepiness due to age. Maybe I am expecting a miracle but for $90 I was hoping for better results
OneSkin18 hours agoHi Hilary,
Thank you so much for taking the time to share this with us — it genuinely means a lot that you trusted us with your honest experience. We can hear how disappointing this has been, and we want you to know that your feelings are completely valid. When you invest in a premium product with real hopes for your skin, you deserve real results.
Crepey skin on the legs and arms is one of the most stubborn concerns to address, and here's why: it develops at the cellular level, where the skin gradually becomes thinner, loses elasticity, and accumulates what scientists call senescent — or "zombie" — cells that accelerate aging. OS-01 BODY was specifically designed to work at that root cause, improving the underlying drivers of crepey skin by supporting epidermal thickness for a firmer look and feel. In lab studies, skin treated with OS-01 BODY showed a significant 40% increase in epidermal thickness compared to untreated skin — which is genuinely remarkable science. But we also know that science on a page doesn't always feel like enough when you're not seeing it in the mirror yet.
With daily use, most people begin to see visible results within 12 weeks — and for some, even sooner. This timeline exists because the OS-01 peptide works at the cellular level, and meaningful structural change — especially in areas like the legs and arms that may have years of thinning to address — simply takes time to emerge. That's not an excuse; it's just the honest biology of how skin renewal works.
We'd love the chance to personally connect with you — to understand your routine, how long you've been using OS-01 BODY, and whether there's anything we can do to help set you up for the best possible outcome. Our team genuinely cares about making this work for you!
Please reach out to us directly at support@oneskin.co — we're here, we're listening, and we're committed to making sure your experience with OneSkin feels worth it.
