OS-01 Topical Supplement FACE, 50 mL

The first skin longevity treatment that extends skin health on the molecular level to address aging from within. Formulated for areas of your skin that are most exposed to environmental damage, including your face, hands, and neck.

  •  Developed by longevity scientists
  •  Safe and clean
  •  For all skin types
  •  Vegan & Cruelty-Free
  • Flagrance free Fragrance-Free

How to use

  • Apply 1-2 pumps onto skin as a daily moisturizer.
  • Where: Face, neck and hands.
  • When: Morning and evening after cleansing.

Ingredients

Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. *OS-01 Peptide.

FAQs

What is a topical supplement?
Just like you take vitamins everyday for general health and immunity, our topical supplement delivers OS-01, a proprietary peptide that extends your skin health (aka your skinspan). Unlike other skincare products that offer short-term solutions (and might even cause long-term damage), we target one of the root causes of aging on the molecular level for long-term results.
Why is OS-01 delivered topically?
This allows for our peptide to be applied to a specific area of skin to maximize penetration and efficacy. In the lab, we measure how OS-01 affects both the dermis and epidermis specifically. More importantly, ingestible supplements often degrade in stomach acid and therefore have no direct effect on the skin, but when applied topically there can be real (and measurable) changes.
Is your topical supplement safe?
We’ve applied the same scientific rigor into formulating a safe product as we did for effectiveness. EWG rates ingredients on a scale of 1-10, with a score of 1 being the safest and healthiest. OS-01 received an average score of 1.02 and a weighted average of 1.04. Our supplement was tested for human sensitization (RIPT - a clinical study to assess skin irritation) and various other toxicity tests, and no adverse effects were found. Note: score of 1.02 reflects our weighted average and 1.04 reflect our average.
How should I integrate the topical supplement into my current skincare routine?
At its core, our topical skin supplement is a moisturizer, so we recommend applying the product after cleansing and before applying a sunscreen. The good news is that our product has not been shown to have adverse reactions with other products, so you can safely incorporate it into your current routine without any additional changes.
How does your topical supplement compare to retinol?
We’re safer and more effective. Retinol targets the symptoms of aging and, when misused or overused, can cause long-term damage to skin by the constant peeling off of epidermal layers. In contrast, OS-O1 targets the root cause of skin aging at the molecular level by preventing the accumulation of senescent cells.
Do you ship internationally?
Unfortunately, we currently only ship to the US, but we’re actively working to change this. Sign up for our newsletter to stay in the know for updates as we continue to expand.
What is the approximate shelf life for your topical supplement ? How should it be stored?
Our topical supplement has a shelf life of 16 months. Refer to the QR code on the back of your bottle for more details.
Is your topical supplement safe for pregnancy / breastfeeding?
Our topical supplement is as safe and effective as can be. We have rigorously tested it’s safety on various skin types, however, we have not tested it on pregnant or breastfeeding mothers. Because of this, we recommend pregnant and breastfeeding mothers show our ingredients list to your doctor or health care provider to confirm its safety before using.
Is your packaging recyclable?
We are working diligently towards making our packaging 100% recyclable. Currently, once you have finished using our product, you can request a free shipping label to return the empty packaging to us. Also, we have partnered with Zero Carbon to offset our carbon footprint to zero! Stay tuned for more updates on our sustainability goals!
What is skinspan?
Skinspan refers t o the length of time that your skin is healthy. Our mission is to extend your skinspan by optimizing skin health on a molecular level and increasing skin strength.
How long will my OS-01 Topical Supplement last?
We estimate the 50 ml bottle of our Topical Supplement will last approximately 2-3 months when used as directed.

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average rating 4.8 out of 5
  • 5 Stars
    102 Reviews
  • 4 Stars
    25 Reviews
  • 3 Stars
    7 Reviews
  • 2 Stars
  • 1 Star
97% of reviewers would recommend this product to a friend
Group 28 INCREASE EPIDERMAL THICKNESS
Fewer wrinkles and more protection against external stressors
Group 25 SUPPORT DNA DAMAGE REPAIR
Improves overall cell function
Group 30 PREVENT THE ACCUMULATION OF AGED CELLS
Helps maintain youthful and healthy skin
varinha-magica (1) IMPROVE COLLAGEN PRODUCTION
Increases skin firmness and strength
Group 31 IMPROVE SKIN TEXTURE AND SMOOTHNESS
Makes your skin feel and look great
water-tank INCREASE SKIN HYDRATION
Reduces water loss and supports production of hyaluronic acid

Elevate your skincare routine

Firmer, Smoother, and Stronger Skin.

Scientifically and Clinically backed

OS-01 Supporting Data

We performed a 12-week clinical study to validate and quantify the impact of OS-01 in improving skin health. Our results showed that OS-01 is clinically proven to strengthen the skin barrier in addition to providing remarkable visual benefits.

12 Weeks
Base Line
  • Improved Skin Barrier (Average Improvement + 15%)*
  • Improved Skin Elasticity (Shown in 90% of users)**
  • Improved Skin Evenness,
    Radiance, Pores, & Firmness (Shown in 95.5% of users)**
  • Less Wrinkles (Shown in 87% of users)
  • Improved Skin Smoothness
    & Overall Appearance (Shown in 100% of users)

*Instrumental Evaluation - Vapometer analysis

*Double-blind expert clinical grader evaluation

Proprietary and high quality

Active Ingredients

Reviews

average rating 4.7 out of 5
Based on 149 reviews
  • 5 Stars
    112 Reviews
  • 4 Stars
    27 Reviews
  • 3 Stars
    10 Reviews
  • 2 Stars
    0 Reviews
  • 1 Star
    0 Reviews
96% of reviewers would recommend this product to a friend
Quality
Rated 4 out of 5
Feel good factor
Rated 4 out of 5
Customer photos and videos
Review posted
Reviewed by Em
Verified Buyer
Age Range
45 - 54
Gender
F
My results
  • Smoother skin
Skin type
Sensitive
Rated 5 out of 5

Better every day

So pleased with this product...and I've tried them all. My skin is softer, less dry and flaky. And that's only after a couple of weeks of use! It's easy to apply, has a pleasant non-odor, and soaks right in. Appreciate the thoughtful science behind the ingredients. I have patch-tested as allergic to a number of common cosmetic ingredients, but this calms my irritated lupus-face like nothing else, with no reactions at all. I wish it were more affordable so that everyone's skin could be healthier. I do ration it so that I can spread the cost out over a few months.

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Quality
Rated 5 out of 5
Feel good factor
Rated 5 out of 5
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Review posted
Reviewed by Dawn Marnel L.
Verified Buyer
Age Range
45 - 54
Gender
F
My results
  • Glowing skin
  • Smoother skin
  • Firmer skin
  • Reduced lines and wrinkles
Skin type
Normal
Rated 5 out of 5

Finally! Nutrition for my skin!

As a super skin care enthusiast, I have spent thousands of dollars on skin care. That stops right here, right now. After trying One Skin, the results are undeniable even after a mere month. I highly recommend One Skin as a standalone product that can be used after cleansing morning and night. I have never had such soft, clear, radiant skin. The skin along my neck and jaw area has tightened and thickened even after such a short time. The skin around my eyes has also thickened in the crow's feet are practically gone. I am truly amazed at the efficacy of this product. Because I am a fanatical researcher of skin care products, I could not deny the scientific proof behind this amazing skin care product. It is worth every cent. And truthfully, as a standalone product, I am literally saving hundreds a month in skin care products. It has taken the place of everything except cleanser. I even use it on my lips and eyelids and cannot believe the change in the color of my lips and the texture of them. Hail to the makers of One Skin! A million thanks! From a devoted user.... Forever.... Now please, can you develop a lotion for my body? 😊

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Quality
Rated 5 out of 5
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Rated 5 out of 5
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Review posted
Reviewed by Rachel
Verified Buyer
Age Range
35 - 44
Gender
F
My results
  • Reduced lines and wrinkles
  • Glowing skin
  • Smoother skin
Skin type
Combination
Rated 5 out of 5

Aging in reverse!

After about five weeks of use, my skin is noticeably brighter and softer! It feels more hydrated, and many of the fine lines that used to appear throughout a long day no longer show up! I feel like my skin truly looks younger!

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I recommend this product
Quality
Rated 5 out of 5
Feel good factor
Rated 5 out of 5
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Review posted
Reviewed by Ivan
Verified Buyer
Age Range
25 - 34
Gender
M
My results
  • Smoother skin
Skin type
Oily
Rated 5 out of 5

I like the product

Ive been using it for a couple of months. I definitely see that my skin became smoother. It is not oily at all!

We’ll see how it works in a year in terms of before/after.

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I recommend this product
Quality
Rated 5 out of 5
Feel good factor
Rated 5 out of 5
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Review posted
Reviewed by Ashley
Age Range
25 - 34
Gender
F
My results
  • Smoother skin
Skin type
Combination
Rated 5 out of 5

Skin feels smoother

I can already tell how different the texture of my skin is! It feels so silky when I wash my face now. And it’s only been two weeks!

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I recommend this product
Quality
Rated 5 out of 5
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Rated 5 out of 5
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