OS-01 Topical Supplement FACE, 50 mL

The first skin longevity treatment that extends skin health on the molecular level to address aging from within. Formulated for areas of your skin that are most exposed to environmental damage, including your face, hands, and neck.

  •  Developed by longevity scientists
  •  Safe and clean
  •  For all skin types
  •  Vegan & Cruelty-Free
  • Flagrance free Fragrance-Free

How to use

  • Apply 1-2 pumps onto skin as a daily moisturizer.
  • Where: Face, neck and hands.
  • When: Morning and evening after cleansing.

Ingredients

Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. *OS-01 Peptide.

FAQs

What is a Topical Supplement?
Just like you take vitamins and oral supplements everyday for your general health and immunity, a Topical Supplement is a formulation designed to improve the health and appearance of the skin.
Topical Supplements are applied to specific areas of the skin to deliver targeted, visible results. Our Topical Supplements deliver OS-01, a proprietary peptide that extends your skin health, or your skinspan.
What is skinspan?
Skinspan refers to the length of time that your skin is healthy. For many, healthy skin presents as supple, smooth, and strong. Our mission is to extend your skinspan by optimizing skin health on a molecular level, increasing skin resilience and strength.
Unlike other skincare products that offer short term solutions (and might even cause long-term damage), our Topical Supplements target the root causes of aging, including cellular damage and the accumulation of aged cells, for long term, visible results.
How is OS-01 FACE formulated for use on areas exposed to the most damage (face, hands, and neck)?
The skin on the face, neck, décolletage, and hands is thinner and more delicate than the rest of the skin on the body. These areas of thin, delicate skin are the most likely to wrinkle, sag, lose elasticity, and show visible signs of premature aging.
Additionally, the delicate skin on the face, neck, décolletage, and hands are most exposed to (environmental) stressors like the sun, UV rays, dry air, cold and windy weather, air pollution, and other external sources that damage the skin’s health, vitality, and appearance.
In order to combat environmental damages and premature aging of the facial skin, OS-01 FACE delivers an optimized concentration of the OS-01 peptide to reduce the skin’s biological age, support powerful cellular repair, and boost barrier function.

OS-01 FACE specifically benefits the more delicate skin of the face, neck, and hands by:

  • Sorting cellular repair and barrier function
  • Increasing epidermal thickness
  • Supporting collagen and elastin production, for stronger, firmer skin0
  • Supporting hyaluronic acid production, to boost hydration
  • Minimizing redness
  • Increasing skin silkiness and smoothness
We recommend applying OS-01 FACE to the most delicate and/or damaged/exposed areas of your skin, like the face, hands, and neck.
For all other areas, we recommend using OS-01 BODY.
Why is OS-01 FACE delivered topically?
Topical delivery ensures maximal penetration by the OS-01 peptide and efficacy to a specific area of skin. Through targeted topical application, the OS-01 FACE Topical Supplement is best able to deliver visible, noticeable improvements to the skin.
It’s also important to note that the science on the efficacy of ingestible skincare supplements is still out. Ingestible skincare supplements often degrade in stomach acid and fail to deliver any quantifiable, noticeable benefits to the skin. Combined with a healthy and balanced diet, Topical Supplements are your most effective tool to achieve faster, more visible improvements to the skin.
Is OS-01 FACE safe?
We’ve applied vigorous scientific rigor and exacting standards into formulating the safest, most effective Topical Supplements possible.
The Environmental Working Group (EWG) rates skincare ingredients on a scale of 1-10, with a score of 1 being the safest and healthiest. OS-01 FACE received an average score of 1.02 and a weighted average of 1.04 on the EWG’s SkinDeep Cosmetics Database.
OS-O1 FACE was tested for human sensitization (RIPT - a clinical study to assess skin irritation) and various other toxicity tests. No adverse effects were found.
OS-01 FACE is clean, vegan, and cruelty free.
How should I integrate the OS-01 FACE into my current skincare routine?
At its core, our Topical Supplements are moisturizers, so we recommend applying after cleansing and before sunscreen.
OS-01 FACE has not been shown to produce adverse reactions with other products and can be safely incorporated into your current routine.
Remember, it’s always best to patch test any new skincare product.
How does OS-01 FACE compare to retinol?
OS-01 FACE is safer and more effective than retinol.
Retinol targets the symptoms of aging by stimulating cell renewal which leads to peeling off the upper epidermal layers. However, retinol is often too harsh for many skin types, especially sensitive and drier skin. Negative side effects of retinol can include redness, irritation, dryness, flaking, and damage to the skin barrier which can increase skin sensitivity. When misused or overused, retinol can even compromise skin health in the long term. Skin thinning and a less resilient, weaker skin barrier are potential outcomes of such misuse.
OS-O1 FACE is a safer, highly efficacious topical skincare supplement that targets the root cause of skin aging at the molecular level by preventing the accumulation of damaged cells and increasing cellular repair capabilities. OS-01 FACE is more gentle than retinol - and our data supports similar or better effects in improving collagen and hyaluronic acid production.
Do you ship internationally?
Currently, we only ship to the U.S. and Canada.
We are working on adding international shipping options. Sign up for our newsletter for updates as we continue to expand.
What is the approximate shelf life of OS-01 FACE? How should it be stored?
OS-01 FACE has a shelf life of 24 months. Refer to the QR code on the back of your bottle for more details.
Is OS-01 FACE safe for pregnancy / breastfeeding?
We have rigorously tested our Topical Supplement for its safety on various skin types, however, we have not tested OS-01 FACE with pregnant or breastfeeding mothers.
We recommend pregnant and breastfeeding mothers show the ingredients list to a doctor or healthcare provider to confirm safety before use. As always, it’s best to consult with a medical professional before making lifestyle changes.
Is your packaging recyclable?
We are working diligently towards making our packaging 100% recyclable.
We offer free shipping labels so you can easily return empty packaging to us. To request a free shipping label please email us at support@oneskin.co.
Is OS-01 FACE sustainable / environmentally friendly / carbon neutral?
We are committed to environmental sustainability and protecting the plant. We constantly aim to reduce our environmental impact while creating cutting-edge, scientifically formulated Topical Supplements that improve the health, appearance, and vitality of the skin.
We partner with Zero Carbon to offset our carbon footprint to zero.
Stay in the loop about our sustainability goals, product news, and more by signing up for our newsletter here.
How long will my OS-01 Topical Supplement last?
The 50 mL bottle of OS-01 FACE will last approximately 2-3 months, when used as directed.
Have any more questions?
For our comprehensive FAQ list click here.

Healthy Skin
Starts Within

There’s more to aging than just the wrinkles you see.

OS-01 FACE addresses the root causes of aging so skin doesn’t just look younger, it actually functions like younger skin.

OS-01
Face

146 Reviews

The first skin longevity treatment that extends skin health on the molecular level to address aging from within.

Select your plan

30 day money back guarantee We are confident you will be more than satisfied with our product so much so that we offer a 30-day money back guarantee on your first order. What this means is, you can request a refund at any point within 30 days of your first purchase of the product and get your money back with no questions asked. That's how much we believe in our product! We do want to note, based on feedback, most customers state results around the 6 week mark of continued use. [ + ] read more Try it risk-free!

149 Reviews

would recommend this product to a friend
Group 28 INCREASE EPIDERMAL THICKNESS
Fewer wrinkles and more protection against external stressors
Group 25 SUPPORT DNA DAMAGE REPAIR
Improves overall cell function
Group 30 PREVENT THE ACCUMULATION OF AGED CELLS
Helps maintain youthful and healthy skin
varinha-magica (1) IMPROVE COLLAGEN PRODUCTION
Increases skin firmness and strength
Group 31 IMPROVE SKIN TEXTURE AND SMOOTHNESS
Makes your skin feel and look great
water-tank INCREASE SKIN HYDRATION
Reduces water loss and supports production of hyaluronic acid

Elevate your skincare routine

Firmer, Smoother, and Stronger Skin.

Scientifically and Clinically backed

OS-01 Supporting Data

As we age, our skin becomes less efficient at clearing away damaged cells that weaken healthy cells around them. The accumulation of damaged cells reduces skin resilience and triggers wrinkles, dark spots, and loss of firmness. OS-01 reduces the accumulation of damaged cells so that skin stays healthier for longer. In a 12-week clinical study, OS-01 was shown to:

12 Weeks
Base Line
  • Improve Skin Barrier (Average Improvement + 15%)*
  • Improve Skin Elasticity (Shown in 90% of users)**
  • Improve Skin Evenness,
    Radiance, Pores, & Firmness (Shown in 95.5% of users)**
  • Reduce Appearance of Fine Lines & Wrinkles (Shown in 87% of users)
  • Improve Skin Smoothness
    & Overall Appearance (Shown in 100% of users)

*Instrumental Evaluation - Vapometer analysis

*Double-blind expert clinical grader evaluation

Active Ingredients

Seven supporting ingredients that work with OS-01 to boost moisture, reinforce barrier function, and diminish skin stress



Reviews

average rating 4.7 out of 5
Based on 149 reviews
  • 5 Stars
    112 Reviews
  • 4 Stars
    27 Reviews
  • 3 Stars
    10 Reviews
  • 2 Stars
    0 Reviews
  • 1 Star
    0 Reviews
96% of reviewers would recommend this product to a friend
Quality
Rated 4 out of 5
Feel good factor
Rated 4 out of 5
Customer photos and videos
Review posted
Reviewed by Em
Verified Buyer
Age Range
45 - 54
Gender
F
My results
  • Smoother skin
Skin type
Sensitive
Rated 5 out of 5

Better every day

So pleased with this product...and I've tried them all. My skin is softer, less dry and flaky. And that's only after a couple of weeks of use! It's easy to apply, has a pleasant non-odor, and soaks right in. Appreciate the thoughtful science behind the ingredients. I have patch-tested as allergic to a number of common cosmetic ingredients, but this calms my irritated lupus-face like nothing else, with no reactions at all. I wish it were more affordable so that everyone's skin could be healthier. I do ration it so that I can spread the cost out over a few months.

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Quality
Rated 5 out of 5
Feel good factor
Rated 5 out of 5
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Review posted
Reviewed by Dawn Marnel L.
Verified Buyer
Age Range
45 - 54
Gender
F
My results
  • Glowing skin
  • Smoother skin
  • Firmer skin
  • Reduced lines and wrinkles
Skin type
Normal
Rated 5 out of 5

Finally! Nutrition for my skin!

As a super skin care enthusiast, I have spent thousands of dollars on skin care. That stops right here, right now. After trying One Skin, the results are undeniable even after a mere month. I highly recommend One Skin as a standalone product that can be used after cleansing morning and night. I have never had such soft, clear, radiant skin. The skin along my neck and jaw area has tightened and thickened even after such a short time. The skin around my eyes has also thickened in the crow's feet are practically gone. I am truly amazed at the efficacy of this product. Because I am a fanatical researcher of skin care products, I could not deny the scientific proof behind this amazing skin care product. It is worth every cent. And truthfully, as a standalone product, I am literally saving hundreds a month in skin care products. It has taken the place of everything except cleanser. I even use it on my lips and eyelids and cannot believe the change in the color of my lips and the texture of them. Hail to the makers of One Skin! A million thanks! From a devoted user.... Forever.... Now please, can you develop a lotion for my body? 😊

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Quality
Rated 5 out of 5
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Rated 5 out of 5
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Review posted
Reviewed by Rachel
Verified Buyer
Age Range
35 - 44
Gender
F
My results
  • Reduced lines and wrinkles
  • Glowing skin
  • Smoother skin
Skin type
Combination
Rated 5 out of 5

Aging in reverse!

After about five weeks of use, my skin is noticeably brighter and softer! It feels more hydrated, and many of the fine lines that used to appear throughout a long day no longer show up! I feel like my skin truly looks younger!

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I recommend this product
Quality
Rated 5 out of 5
Feel good factor
Rated 5 out of 5
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Review posted
Reviewed by Ivan
Verified Buyer
Age Range
25 - 34
Gender
M
My results
  • Smoother skin
Skin type
Oily
Rated 5 out of 5

I like the product

Ive been using it for a couple of months. I definitely see that my skin became smoother. It is not oily at all!

We’ll see how it works in a year in terms of before/after.

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I recommend this product
Quality
Rated 5 out of 5
Feel good factor
Rated 5 out of 5
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Review posted
Reviewed by Ashley
Age Range
25 - 34
Gender
F
My results
  • Smoother skin
Skin type
Combination
Rated 5 out of 5

Skin feels smoother

I can already tell how different the texture of my skin is! It feels so silky when I wash my face now. And it’s only been two weeks!

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I recommend this product
Quality
Rated 5 out of 5
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Rated 5 out of 5
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