The future of skin health is here

Shop Now


The first topical supplement designed to extend your skinspan on a molecular level.

As seen on

We have a secret… We aren’t a skincare company

We are a longevity company. Our team is comprised of PhD-level aging experts. We’ve spent years in a lab creating the first topical skin supplement designed to extend your skinspan; the time your skin is healthy and youthful. And here you thought all supplements were pills.

Right for all skin types
(we all age, after all)
Data-backed claims
peptide, OS-01
Developed by longevity Scientists
Vegan and cruelty free
Safe and clean ingredients

Healthy skin is happy skin

(Just take it from our customers!)


“I am seeing a huge improvement in texture. I was using Retin -A for years but this stuff seems to do the same thing without the irritation.”

-Tania S.

“I love that this is a one-step skincare process and that it WORKS. My skin is healthier and clearer than it has been in a very long time. It doesn’t irritate the way products with retinol do.”

-Lisa T.

“I'm feeling very confident that OS-01 has improved my skin significantly -- specifically by improving the appearance of fine lines/wrinkles but also the firmness/plumpness of my skin. I've tried other approaches -- retinol (Drunk Elephant) and copper peptides (The Ordinary) -- but nothing produced results as noticeably or as quickly as this. The fact that my girlfriend didn't see me for the first two weeks that I started the product, and then commented that my skin looked much better when we saw each other next, was a nice bonus too.”

-John D.

“My wife and I love this product. She saw a drastic minimizing of pore size within just a few days of use. Overall, our skin is smoother, more even-toned, and has a healthy glow. It doesn't leave skin looking papery-thin like a retinoid does, but with a "dewy" youthful glow.”


Scientifically and Clinically backed

OS-01 Supporting Data

We performed a 12-week clinical study to validate and quantify the impact of OS-01 in improving skin health. Our results showed that OS-01 is clinically proven to strengthen the skin barrier in addition to providing remarkable visual benefits.

12 Weeks
Base Line
  • Improved Skin Barrier (Average Improvement + 15%)*
  • Improved Skin Elasticity (Shown in 90% of users)**
  • Improved Skin Evenness,
    Radiance, Pores, & Firmness (Shown in 95.5% of users)**
  • Less Wrinkles (Shown in 87% of users)
  • Improved Skin Smoothness
    & Overall Appearance (Shown in 100% of users)

*Instrumental Evaluation - Vapometer analysis

*Double-blind expert clinical grader evaluation

Shop OS-01

Meet OS-O1, the first ingredient to target the root causes of skin aging

Our product acts at the molecular level. Our proprietary peptide, OS-O1, is scientifically proven to

Plus, it will leave you with firmer, smoother, and stronger skin.

Healthy skin is happy skin

(Just take it from our beta testers)

Skin health is a marathon, not a sprint

In the same way you take daily vitamins to keep yourself healthy, daily application of our science-backed topical supplement promotes long-lasting effects.

Rather than creating a quick fix or a temporary relief, OneSkin promotes long-term skin health. Our topical supplement works over time, penetrating the deepest layer of the skin to stimulate change. Most users start seeing healthier, stronger, and better looking skin in 4-8 weeks with daily use.

Learn about our Topical Supplement