Anti-Aging Reinvented

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The first Topical Supplement designed to extend skin health on the molecular level by targeting aging from within.

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We have a secret… We aren’t a skincare company

We are a longevity company. Our team is comprised of PhD-level aging experts. We’ve spent years in a lab creating the first topical skin supplement designed to extend your skinspan; the time your skin is healthy and youthful. And here you thought all supplements were pills.

Right for all skin types
(we all age, after all)
Data-backed claims
peptide, OS-01
Developed by longevity Scientists
Vegan and cruelty free with safe and clean ingredients
Best alternative to retinol

Healthy skin looks great on everyone

(Just take it from our customers!)


“I am seeing a huge improvement in texture. I was using Retin -A for years but this stuff seems to do the same thing without the irritation.”

-Tania S.

“I love that this is a one-step skincare process and that it WORKS. My skin is healthier and clearer than it has been in a very long time. It doesn’t irritate the way products with retinol do.”

-Lisa T.

“I'm feeling very confident that OS-01 has improved my skin significantly -- specifically by improving the appearance of fine lines/wrinkles but also the firmness/plumpness of my skin. I've tried other approaches -- retinol (Drunk Elephant) and copper peptides (The Ordinary) -- but nothing produced results as noticeably or as quickly as this. The fact that my girlfriend didn't see me for the first two weeks that I started the product, and then commented that my skin looked much better when we saw each other next, was a nice bonus too.”

-Josh D.

“My wife and I love this product. She saw a drastic minimizing of pore size within just a few days of use. Overall, our skin is smoother, more even-toned, and has a healthy glow. It doesn't leave skin looking papery-thin like a retinoid does, but with a "dewy" youthful glow.”


“My friend gave it to me as a gift. At first I thought, "Ugh, another useless skincare," but then she told me about all the great scientific proofs and results, so I gave it a try. It really made my skin look better, softer, and small wrinkles disappeared. I can't wait to make another order!"

-Arzu A.

"In a space that is so saturated with overhyped products, it's refreshing to see a brand that stands for evidence, efficacy, and holistic health. My skin feels brighter, softer, and overall smoother, it's my new go-to!"

-Dara E.

“I have always been obsessed with products that have both a health benefit and positive physical impact. And while there are tons of products that claim to do this on the market today, none that I’ve tried have even come close to the visibly measurable improvement in my skin I’ve seen in just 8 weeks! OneSkin is the one product I don’t see ever leaving my skin care routine!”

-Brandon S.

Scientifically and Clinically backed

OS-01 Supporting Data

We performed a 12-week clinical study to validate and quantify the impact of OS-01 in improving skin health. Our results showed that OS-01 is clinically proven to strengthen the skin barrier in addition to providing remarkable visual benefits.

12 Weeks
Base Line
  • Improved Skin Barrier (Average Improvement + 15%)*
  • Improved Skin Elasticity (Shown in 90% of users)**
  • Improved Skin Evenness,
    Radiance, Pores, & Firmness (Shown in 95.5% of users)**
  • Less Wrinkles (Shown in 87% of users)
  • Improved Skin Smoothness
    & Overall Appearance (Shown in 100% of users)

*Instrumental Evaluation - Vapometer analysis

*Double-blind expert clinical grader evaluation

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Meet OS-O1, the first ingredient to target the root causes of skin aging

Our product acts at the molecular level. Our proprietary peptide, OS-O1, is scientifically proven to

Plus, it will leave you with firmer, smoother, and stronger skin, making it the perfect substitute for retinol and other top-rated anti-aging products.

Healthy skin is happy skin

(Just take it from our beta testers)


As a brand whose mission is to inspire healthy aging, we don’t identify with the term “anti-aging” and here’s why:

Much of the anti-aging skincare industry has been built on empty promises with top anti-aging products lacking validated claims and exploiting age-related anxiety and fear.

At OneSkin, we recognize that the goal of the best anti-aging skincare products shouldn't be only to improve appearances, which often forces consumers to compromise on long-term skin health, but rather to treat the underlying source of skin aging, a consequence of which will be improved appearances.

We are developing best-in-class solutions to aging with a new mindset - one that’s not anti-aging, but pro-aging in the healthiest and most beautiful way possible. We believe the best anti-aging treatment is one that is rooted in science, with data-backed claims. That’s why our Topical Supplement goes beyond placing a metaphorical band-aid on aging skin — it addresses the molecular changes associated with aging to not only boost skin health, but overall health as well.

Skin health is a marathon, not a sprint

In the same way you take daily vitamins to keep yourself healthy, daily application of our science-backed topical supplement promotes long-lasting effects.

Unlike other top-rated anti-aging treatments, such as retinol, which promise quick fixes and may even be damaging in the long run, OneSkin promotes long-term skin health at the molecular level. Our topical supplement works over time, penetrating the deepest layer of the skin to stimulate change, making OneSkin the best alternative to retinol for wrinkles and other signs of aging. Most users start seeing healthier, stronger, and better looking skin in 4-8 weeks with daily use.

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A Better Alternative to Retinol, Botox, and Fillers

OS-01 works beyond the surface to support lasting skin health without the harsh side effects of retinol or the invasiveness of Botox and fillers.

OS-01 Retinoids Hyaluronic Acid Dermal Fillers Botulinum Toxin Injections
Diminishes the appearance of fine lines and wrinkles x x x x
Improves skin firmness and loss of volume x x x
Increases epidermal thickness x x x
Improves skin texture x x x
Non-invasive treatment x x
Doesn’t cause skin irritation or redness x
Prevents the accumulation of damaged cells x
Supports DNA damage repair x
Boosts skin strength and resilience x
Extends skinspan so skin cells act younger for longer x

Discoveries are for those that seek them.

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